Gene expression profiling reveals a regulatory role for ROR alpha and ROR gamma in phase I and phase II metabolism - sprookjes - yvandenbroek - TriplyDB

Gene expression profiling reveals a regulatory role for ROR alpha and ROR gamma in phase I and phase II metabolism

Gene expression profiling reveals a regulatory role for ROR alpha and ROR gamma in phase I and phase II metabolism

http://www.wikidata.org/entity/Q28594055

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Redundant function of REV-ERBalpha and beta and non-essential role for Bmal1 cycling in transcriptional regulation of intracellular circadian rhythms Prospero-related homeobox 1 (Prox1) functions as a novel modulator of retinoic acid-related orphan receptors α- and γ-mediated transactivation Structural basis for hydroxycholesterols as natural ligands of orphan nuclear receptor RORgamma Modulation of retinoic acid receptor-related orphan receptor alpha and gamma activity by 7-oxygenated sterol ligands Mfsd2a encodes a novel major facilitator superfamily domain-containing protein highly induced in brown adipose tissue during fasting and adaptive thermogenesis Orphan nuclear receptors and the regulation of nutrient metabolism: understanding obesity ROR nuclear receptors: structures, related diseases, and drug discovery Regulation of the cytosolic sulfotransferases by nuclear receptors The therapeutic potential of RORγ modulators in the treatment of human disease Chronopharmacology: new insights and therapeutic implications Bile acid signaling in metabolic disease and drug therapy Circadian rhythms in liver metabolism and disease T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma Identification of nuclear localization, DNA binding, and transactivating mechanisms of Kruppel-like zinc finger protein Gli-similar 2 (Glis2)Identification of Differentially Expressed microRNAs between the Fenpropathrin Resistant and Susceptible Strains in Tetranychus cinnabarinus RORγ directly regulates the circadian expression of clock genes and downstream targets in vivo Retinoic acid actions through mammalian nuclear receptors.Diurnal oscillation of amygdala clock gene expression and loss of synchrony in a mouse model of depression.The cytochrome P450 (CYP) gene superfamily in Daphnia pulex Role of multi-hnRNP nuclear complex in regulation of tumor suppressor ANXA7 in prostate cancer cells.Regulation of steroidogenic acute regulatory protein transcription in largemouth bass by orphan nuclear receptor signaling pathways.The transcriptional regulation of the human CYP2C genes The benzenesulfoamide T0901317 [N-(2,2,2-trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-benzenesulfonamide] is a novel retinoic acid receptor-related orphan receptor-alpha/gamma inverse agonist.Retinoic acid-related orphan receptor γ (RORγ): a novel participant in the diurnal regulation of hepatic gluconeogenesis and insulin sensitivity Oxysterols and their cellular effectors.Regulation of FGF21 expression and secretion by retinoic acid receptor-related orphan receptor alpha.A second class of nuclear receptors for oxysterols: Regulation of RORalpha and RORgamma activity by 24S-hydroxycholesterol (cerebrosterol)Garlic extract diallyl sulfide (DAS) activates nuclear receptor CAR to induce the Sult1e1 gene in mouse liver.Control of gene expression by the retinoic acid-related orphan receptor alpha in HepG2 human hepatoma cells.Identification and validation of the pathways and functions regulated by the orphan nuclear receptor, ROR alpha1, in skeletal muscle.Circadian rhythms in gene expression: Relationship to physiology, disease, drug disposition and drug action.Ligand regulation of retinoic acid receptor-related orphan receptors: implications for development of novel therapeutics Retinoid acid-related orphan receptor γ, RORγ, participates in diurnal transcriptional regulation of lipid metabolic genes.Rev-erbα and Rev-erbβ coordinately protect the circadian clock and normal metabolic function Action of RORs and their ligands in (patho)physiology.Small molecule inhibitors of RORγt: targeting Th17 cells and other applications.Regulation of the human hydroxysteroid sulfotransferase (SULT2A1) by RORα and RORγ and its potential relevance to human liver diseases.REV-ERB and ROR nuclear receptors as drug targets.Nuclear orphan receptor TAK1/TR4-deficient mice are protected against obesity-linked inflammation, hepatic steatosis, and insulin resistance.CD44 plays a critical role in regulating diet-induced adipose inflammation, hepatic steatosis, and insulin resistance

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P2860

Gene expression profiling reveals a regulatory role for ROR alpha and ROR gamma in phase I and phase II metabolism

http://www.wikidata.org/entity/Q28594055

description

2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

artículu científicu espublizáu en 2007

@ast

im Oktober 2007 veröffentlichter wissenschaftlicher Artikel

@de

scientific journal article

@en

vedecký článok (publikovaný 2007/10/22)

@sk

vědecký článek publikovaný v roce 2007

@cs

wetenschappelijk artikel (gepubliceerd op 2007/10/22)

@nl

наукова стаття, опублікована в жовтні 2007

@uk

مقالة علمية (نشرت في 22-10-2007)

@ar

name

Gene expression profiling reve ...... hase I and phase II metabolism

@ast

Gene expression profiling reve ...... hase I and phase II metabolism

@en

Gene expression profiling reve ...... hase I and phase II metabolism

@nl

type

label

Gene expression profiling reve ...... hase I and phase II metabolism

@ast

Gene expression profiling reve ...... hase I and phase II metabolism

@en

Gene expression profiling reve ...... hase I and phase II metabolism

@nl

prefLabel

Gene expression profiling reve ...... hase I and phase II metabolism

@ast

Gene expression profiling reve ...... hase I and phase II metabolism

@en

Gene expression profiling reve ...... hase I and phase II metabolism

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PHYSIOLGENOMICS.00098.2007

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Physiological Genomics

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Gene expression profiling reve ...... hase I and phase II metabolism

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Hong Soon Kang

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Jeffrey M Gimble

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Jennifer B Collins

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Ju Youn Beak

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Martin Angers

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Sherry F Grissom

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Taira Wada

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Wen Xie

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Xiying Wu

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P2860

Transcriptional regulation of apolipoprotein C-III gene expression by the orphan nuclear receptor RORalpha

The orphan nuclear receptor ROR alpha is a negative regulator of the inflammatory response

ROR gamma: the third member of ROR/RZR orphan receptor subfamily that is highly expressed in skeletal muscle

Disruption of retinoid-related orphan receptor beta changes circadian behavior, causes retinal degeneration and leads to vacillans phenotype in mice

X-ray structure of the orphan nuclear receptor RORbeta ligand-binding domain in the active conformation.

Retinoid-related orphan receptor gamma (RORgamma) is essential for lymphoid organogenesis and controls apoptosis during thymopoiesis

In vitro and in vivo evidence for orphan nuclear receptor RORalpha function in bone metabolism

X-ray structure of the hRORalpha LBD at 1.63 A: structural and functional data that cholesterol or a cholesterol derivative is the natural ligand of RORalpha

All-trans retinoic acid is a ligand for the orphan nuclear receptor ROR beta

Crystal structure of the human RORalpha Ligand binding domain in complex with cholesterol sulfate at 2.2 A

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281-294

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scholarly article

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1003628

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10.1152/PHYSIOLGENOMICS.00098.2007

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2

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31

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Anton M. Jetten

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2007-07-31T00:00:00Z

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6171823

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17666523

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RAR-related orphan receptor alpha

RAR-related orphan receptor gamma