Deletion of the Ca2+-activated potassium (BK) alpha-subunit but not the BKbeta1-subunit leads to progressive hearing loss
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Ion channel gene expression in the inner earMaxiK channel and cell signallingHypoxia and ischemia-reperfusion: a BiK contribution?Mice with deficient BK channel function show impaired prepulse inhibition and spatial learning, but normal working and spatial reference memory.The Ca2+ channel subunit beta2 regulates Ca2+ channel abundance and function in inner hair cells and is required for hearingSplicing of the rSlo gene affects the molecular composition and drug response of Ca2+-activated K+ channels in skeletal muscleA protein interaction network for the large conductance Ca(2+)-activated K(+) channel in the mouse cochlea.The role of BKCa channels in electrical signal encoding in the mammalian auditory periphery.Mice deficient for the type II transmembrane serine protease, TMPRSS1/hepsin, exhibit profound hearing loss.Mice with altered KCNQ4 K+ channels implicate sensory outer hair cells in human progressive deafness.A novel BK channel-targeted peptide suppresses sound evoked activity in the mouse inferior colliculus.BDNF in Lower Brain Parts Modifies Auditory Fiber Activity to Gain Fidelity but Increases the Risk for Generation of Central Noise After Injury.Activation of BK and SK channels by efferent synapses on outer hair cells in high-frequency regions of the rodent cochlea.Potassium ion movement in the inner ear: insights from genetic disease and mouse modelsRecognition and control of the progression of age-related hearing loss.Hair cell ribbon synapses.Plasticity in ion channel expression underlies variation in hearing during reproductive cyclesOlivocochlear suppression of outer hair cells in vivo: evidence for combined action of BK and SK2 channels throughout the cochlea.Habituation of reflexive and motivated behavior in mice with deficient BK channel function.Critical role for cochlear hair cell BK channels for coding the temporal structure and dynamic range of auditory information for central auditory processingModulation of hair cell efferentsShort-term synaptic plasticity regulates the level of olivocochlear inhibition to auditory hair cellsTamoxifen inhibits BK channels in chick cochlea without alterations in voltage-dependent activationCalcium-activated potassium (BK) channels are encoded by duplicate slo1 genes in teleost fishes.RNA microarray analysis in prenatal mouse cochlea reveals novel IGF-I target genes: implication of MEF2 and FOXM1 transcription factors.SK2 channels are required for function and long-term survival of efferent synapses on mammalian outer hair cells.Endocochlear potential depends on Cl- channels: mechanism underlying deafness in Bartter syndrome IV.Deafness in TRbeta mutants is caused by malformation of the tectorial membrane.Inheritance patterns of progressive hearing loss in laboratory strains of miceDevelopmental expression of BK channels in chick cochlear hair cells.α-Catulin CTN-1 is required for BK channel subcellular localization in C. elegans body-wall muscle cells.A role for BK channels in heart rate regulation in rodentsA BK (Slo1) channel journey from molecule to physiology.BK channels mediate cholinergic inhibition of high frequency cochlear hair cells.Dominant-negative regulation of cell surface expression by a pentapeptide motif at the extreme COOH terminus of an Slo1 calcium-activated potassium channel splice variant.Big Potassium (BK) ion channels in biology, disease and possible targets for cancer immunotherapy.Dual role of protein kinase C on BK channel regulation.Plasticity and emerging role of BKCa channels in nociceptive control in neuropathic pain.CDK5 interacts with Slo and affects its surface expression and kinetics through direct phosphorylationCa(2+) and Ca(2+)-activated K(+) channels that support and modulate transmitter release at the olivocochlear efferent-inner hair cell synapse
P2860
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P2860
Deletion of the Ca2+-activated potassium (BK) alpha-subunit but not the BKbeta1-subunit leads to progressive hearing loss
description
2004 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2004
@ast
im August 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/08/31)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/08/31)
@nl
наукова стаття, опублікована в серпні 2004
@uk
name
Deletion of the Ca2+-activated ...... ds to progressive hearing loss
@ast
Deletion of the Ca2+-activated ...... ds to progressive hearing loss
@en
Deletion of the Ca2+-activated ...... ds to progressive hearing loss
@nl
type
label
Deletion of the Ca2+-activated ...... ds to progressive hearing loss
@ast
Deletion of the Ca2+-activated ...... ds to progressive hearing loss
@en
Deletion of the Ca2+-activated ...... ds to progressive hearing loss
@nl
prefLabel
Deletion of the Ca2+-activated ...... ds to progressive hearing loss
@ast
Deletion of the Ca2+-activated ...... ds to progressive hearing loss
@en
Deletion of the Ca2+-activated ...... ds to progressive hearing loss
@nl
P2093
P2860
P50
P356
P1476
Deletion of the Ca2+-activated ...... ds to progressive hearing loss
@en
P2093
Alfons Rüsch
Bernhard Hirt
Claudia Arntz
Harald Winter
Imke Pfaff
Jutta Engel
Marcus Müller
Markus Pfister
Martina Knirsch
Matthias Sausbier
P2860
P304
12922–12927
P356
10.1073/PNAS.0402660101
P407
P577
2004-08-31T00:00:00Z