A role for Groucho tetramerization in transcriptional repression - sprookjes - yvandenbroek - TriplyDB

A role for Groucho tetramerization in transcriptional repression

A role for Groucho tetramerization in transcriptional repression

http://www.wikidata.org/entity/Q28609165

about

Transducin-like enhancer of split proteins, the human homologs of Drosophila groucho, interact with hepatic nuclear factor 3beta A core SMRT corepressor complex containing HDAC3 and TBL1, a WD40-repeat protein linked to deafness Pf1, a novel PHD zinc finger protein that links the TLE corepressor to the mSin3A-histone deacetylase complex The proline-rich homeodomain protein recruits members of the Groucho/Transducin-like enhancer of split protein family to co-repress transcription in hematopoietic cells Groucho binds two conserved regions of LEF-1 for HDAC-dependent repression The PRH/Hex repressor protein causes nuclear retention of Groucho/TLE co-repressors Molecular functions of the TLE tetramerization domain in Wnt target gene repression Role for the mortality factors MORF4, MRGX, and MRG15 in transcriptional repression via associations with Pf1, mSin3A, and Transducin-Like Enhancer of Split.Oligomerization of ETO is obligatory for corepressor interaction Transcriptional repression by Pax5 (BSAP) through interaction with corepressors of the Groucho family Temporal regulation of a paired-like homeodomain repressor/TLE corepressor complex and a related activator is required for pituitary organogenesis All Tcf HMG box transcription factors interact with Groucho-related co-repressors Gbx2 and Otx2 interact with the WD40 domain of Groucho/Tle corepressors Repression by Groucho/TLE/Grg proteins: genomic site recruitment generates compacted chromatin in vitro and impairs activator binding in vivo Structure of the C-terminal domain of Tup1, a corepressor of transcription in yeast A new Groucho TLE4 protein may regulate the repressive activity of Pax5 in human B lymphocytes Cell Fate and Differentiation of Bone Marrow Mesenchymal Stem Cells Crystal Structure of the N-terminal Domain of the Yeast General Corepressor Tup1p and Its Functional Implications Cloning and characterization of a novel WD-40 repeat protein that dramatically accelerates osteoblastic differentiation rTLE3, a newly identified transducin-like enhancer of split, is induced by depolarization in brain Characterization of a novel mammalian Groucho isoform and its role in transcriptional regulation A functional interaction between the histone deacetylase Rpd3 and the corepressor groucho in Drosophila development The homeodomain protein NK-3 recruits Groucho and a histone deacetylase complex to repress transcription Groucho oligomerization is required for repression in vivo Functional dissection of the global repressor Tup1 in yeast: dominant role of the C-terminal repression domain.Analysis of the transcription factor WUSCHEL and its functional homologue in Antirrhinum reveals a potential mechanism for their roles in meristem maintenance.Phosphorylation of SU(VAR)3-9 by the chromosomal kinase JIL-1.Groucho-mediated repression may result from a histone deacetylase-dependent increase in nucleosome density.Differential modulation of TCF/LEF-1 activity by the soluble LRP6-ICD.Transcriptional autoregulation and inhibition of mRNA translation of amino acid regulator gene cpcA of filamentous fungus Aspergillus nidulans The corepressor Tle4 is a novel regulator of murine hematopoiesis and bone development.The unconserved groucho central region is essential for viability and modulates target gene specificity.AES/GRG5: more than just a dominant-negative TLE/GRG family member Role for Hes1-induced phosphorylation in Groucho-mediated transcriptional repression.The Dorsal Rel homology domain plays an active role in transcriptional regulation Regulation of SMRT corepressor dimerization and composition by MAP kinase phosphorylation.GRG5/AES interacts with T-cell factor 4 (TCF4) and downregulates Wnt signaling in human cells and zebrafish embryos.Keeping a good pathway down: transcriptional repression of Notch pathway target genes by CSL proteins The Groucho co-repressor is primarily recruited to local target sites in active chromatin to attenuate transcription An ancient Pygo-dependent Wnt enhanceosome integrated by Chip/LDB-SSDP.

P2860

Q22253477-9C713476-CDF1-4ED3-A229-16DE2A9B1496 Q22254089-76AE242E-E05A-40DA-9F74-734462690908 Q24291300-ED960573-FE48-437B-B50D-85BF56350947 Q24296022-463E453D-9761-4297-BFFD-88551E841EC8 Q24312550-BA092B31-DF52-4CE0-93A0-5B8F58EB2D0E Q24324330-46DFE865-576F-4FDF-AFB7-2566D4FAA78C Q24338688-71EFDDBC-2A3B-4347-B4F9-F1CF9AFAB1D2 Q24538543-45D29207-2549-4E90-A221-CECCC756A01C Q24550754-6E7DEB4C-0417-4FC3-A0AD-E884601C2090 Q24594237-7A394983-F029-4939-88D4-1BC2913995F4 Q24599714-A4CBB64A-868D-406B-8648-0A9BB0E26C41 Q24599779-A4F79984-99D1-4776-BC57-10D73673A30E Q24674174-C955D3F5-C126-4C6E-BCA8-9C13E20657DA Q24674585-EFA0276C-3BA0-4A37-98D7-B15686033A1A Q24678778-CA892D3C-7D9D-44CF-B1BE-771BBD328BCC Q24682733-E0A9B7BA-15A1-41CB-9BF2-B039192E6A12 Q26746170-DD1E6043-5DFF-41FC-B686-093F1E33BFBA Q27681213-7E3A8EEF-40A8-4003-8973-CC54C10F2F5F Q28508822-B9D05947-7B45-491C-B30D-EA15637C66A2 Q28575042-EDAAA4BE-4A92-43CF-A70F-ABF9295DCB77 Q28589997-1C3E06D2-CB9C-4ABD-BF33-924E5135CBDC Q28609065-EAB18FF8-9E50-4D49-A36D-31ACE0572B9E Q28609066-B54F7DDC-9C5B-4668-83C9-99345378EC31 Q28609105-0E1A35C7-F4C1-43A6-8635-8D892F15D894 Q31097669-A6CE9488-F455-489A-9715-CBAC48FA8D42 Q33342084-B0765063-F564-4911-BE13-C43482FEE575 Q33553206-AA123995-DCBC-4E91-AB9D-BC664B8FD6F3 Q33559830-2D5C1747-75D0-47DC-8B9A-F9EFA5D44A06 Q33646702-DDA96DED-932E-41F9-A8E8-AF05B298C44F Q33946777-1579258D-D10C-4D22-914D-14746DB4A078 Q34083894-B66805CF-A35B-47AE-AC1F-49B200F901A7 Q34154603-CE9A6509-8893-4933-9B42-491B99137FD4 Q34381620-7EE96D56-A4F6-4419-9A0B-303E44D13BDD Q34440560-D7A33717-EA7B-4349-B476-AADC653536E2 Q34441899-117BD222-4D0B-4EBE-B89F-7AC7D14F2964 Q34444363-684C3E10-0EC9-465B-A331-AC5E93B0E5D5 Q34809015-8F61B3EC-A2C2-41CA-83F4-CF99AB7FB64B Q34838458-6DDF520A-E7E3-4445-91C9-739AEFAE9680 Q35233511-118CD4C7-36DD-40A0-8BCF-4F56043DC2CA Q36064635-E61BD1E1-6D8F-4B7D-8152-0C451C781E65

P2860

A role for Groucho tetramerization in transcriptional repression

http://www.wikidata.org/entity/Q28609165

description

1998 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1998 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

artículu científicu espublizáu en 1998

@ast

im Dezember 1998 veröffentlichter wissenschaftlicher Artikel

@de

scientific journal article

@en

vedecký článok (publikovaný 1998/12/01)

@sk

vědecký článek publikovaný v roce 1998

@cs

wetenschappelijk artikel (gepubliceerd op 1998/12/01)

@nl

наукова стаття, опублікована в грудні 1998

@uk

مقالة علمية (نشرت في ديسمبر 1998)

@ar

name

A role for Groucho tetramerization in transcriptional repression

@ast

A role for Groucho tetramerization in transcriptional repression

@en

A role for Groucho tetramerization in transcriptional repression

@nl

type

label

A role for Groucho tetramerization in transcriptional repression

@ast

A role for Groucho tetramerization in transcriptional repression

@en

A role for Groucho tetramerization in transcriptional repression

@nl

prefLabel

A role for Groucho tetramerization in transcriptional repression

@ast

A role for Groucho tetramerization in transcriptional repression

@en

A role for Groucho tetramerization in transcriptional repression

@nl

P1433

Q28609165-7E26A9EF-1C8A-46E9-978E-AA0A8C37CC98

P1476

Q28609165-B35CDB5D-C757-4DD6-897D-0249D16DC885

P2093

Q28609165-0D2D260A-20D1-4A8B-8333-20FE8AC30029

Q28609165-75908A40-31EC-47D8-93D0-26F495A9A109

Q28609165-F0C5C411-1655-489C-BCE5-BCB9ACC98803

P2860

Q28609165-0621EB50-332D-4568-95C0-3D3C2BE40739

Q28609165-06DF46C3-D0B2-441E-ACC0-A1863532EC25

Q28609165-10C4FB35-B860-4959-A700-ED7339C28CF2

Q28609165-11580B37-8909-48DB-A2B9-CDD19FE6CAFB

Q28609165-116B63B7-EAB5-4286-AA7D-88F0AF3BEBE4

Q28609165-12984C80-D56C-4219-9D5A-C0EF752E5A75

Q28609165-209830C7-9E24-46FF-A629-C437867906CF

Q28609165-24420A57-0472-4B7D-99F8-F5109BBBE30A

Q28609165-255825F7-FA6B-4A1D-89AD-AEC5FD14DEFE

Q28609165-2CB52073-3F0F-4C8A-8183-1EE56ED7187D

P304

Q28609165-A41CD155-77F6-4068-8B9A-12A4E60DABE0

P31

Q28609165-2608BB3D-5633-4876-941F-152A66D96598

P3181

Q28609165-5D581AB6-469B-4B3B-8572-F8E7181CE5A7

P356

Q28609165-12F11E73-71BD-4E56-90FC-75FAAF0146FB

P407

Q28609165-E6443648-4A56-4040-8BEB-16D8862AA1CD

P433

Q28609165-E2CFA758-149D-4D03-899B-FE4D2D1DA5C7

P478

Q28609165-DF61E143-1A31-4579-B37A-2B5E5BB026D7

P577

Q28609165-8561012B-7096-4BB1-AE85-2BCEBD66DDA4

P698

Q28609165-A0A1F59D-4210-4F85-9990-C50AF1525585

P932

Q28609165-8BC56386-DD66-40DD-A156-2EC0F8E2A4A3

P3181

P356

P1433

Molecular and Cellular Biology

P1476

A role for Groucho tetramerization in transcriptional repression

@en

P2093

A. J. Courey

http://www.w3.org/2001/XMLSchema#string

G. Chen

http://www.w3.org/2001/XMLSchema#string

P. H. Nguyen

http://www.w3.org/2001/XMLSchema#string

P2860

CENP-E is a putative kinetochore motor that accumulates just before mitosis

The mouse segmentation gene kr encodes a novel basic domain-leucine zipper transcription factor

Human homologs of a Drosophila Enhancer of split gene product define a novel family of nuclear proteins

Affinity for the nuclear compartment and expression during cell differentiation implicate phosphorylated Groucho/TLE1 forms of higher molecular mass in nuclear functions

3D domain swapping: a mechanism for oligomer assembly

Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms

High-resolution structure of the oligomerization domain of p53 by multidimensional NMR

The 2.0 A crystal structure of a heterotrimeric G protein

Crystal structure of a G-protein beta gamma dimer at 2.1A resolution

Ssn6-Tup1 is a general repressor of transcription in yeast.

P304

7259–7268

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

1485900

http://www.w3.org/2001/XMLSchema#string

P356

10.1128/MCB.18.12.7259

http://www.w3.org/2001/XMLSchema#string

P407

P433

12

http://www.w3.org/2001/XMLSchema#string

P478

18

http://www.w3.org/2001/XMLSchema#string

P577

1998-12-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

9819412

http://www.w3.org/2001/XMLSchema#string

P932

109307

http://www.w3.org/2001/XMLSchema#string