Constitutive activation of mitogen-activated protein kinase-activated protein kinase 2 by mutation of phosphorylation sites and an A-helix motif
about
A novel role for MAPKAPK2 in morphogenesis during zebrafish developmentC-terminal elements control location, activation threshold, and p38 docking of ribosomal S6 kinase B (RSKB)Stabilization of urokinase and urokinase receptor mRNAs by HuR is linked to its cytoplasmic accumulation induced by activated mitogen-activated protein kinase-activated protein kinase 2MAPKAP kinase 2 phosphorylates tristetraprolin on in vivo sites including Ser178, a site required for 14-3-3 bindingThioredoxin-ASK1 complex levels regulate ROS-mediated p38 MAPK pathway activity in livers of aged and long-lived Snell dwarf miceMAPKAP kinase MK2 maintains self-renewal capacity of haematopoietic stem cells3pK, a novel mitogen-activated protein (MAP) kinase-activated protein kinase, is targeted by three MAP kinase pathwaysOsmotic stress signaling via protein kinasesMolecular basis of MAPK-activated protein kinase 2:p38 assemblyRck2, a member of the calmodulin-protein kinase family, links protein synthesis to high osmolarity MAP kinase signaling in budding yeastThe AU-rich element mRNA decay-promoting activity of BRF1 is regulated by mitogen-activated protein kinase-activated protein kinase 2Endoplasmic reticulum-associated ubiquitin-conjugating enzyme Ube2j1 is a novel substrate of MK2 (MAPKAP kinase-2) involved in MK2-mediated TNFα productionLSP1 is the major substrate for mitogen-activated protein kinase-activated protein kinase 2 in human neutrophilsFRET-based detection of different conformations of MK2.Characterization of the p90 ribosomal S6 kinase 2 carboxyl-terminal domain as a protein kinaseComparative Analysis of Two Gene-Targeting Approaches Challenges the Tumor-Suppressive Role of the Protein Kinase MK5/PRAKScaffolding by ERK3 regulates MK5 in developmentp38 MAPK/MK2-mediated induction of miR-34c following DNA damage prevents Myc-dependent DNA replicationERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functionsSerotonin Receptor 4/6/7 and NR3C SignalingSerotonin Receptor 2 and ELK-SRF/GATA4 signalingGeneration of constitutively active p90 ribosomal S6 kinase in vivo. Implications for the mitogen-activated protein kinase-activated protein kinase family.Proteomic identification of 14-3-3zeta as a mitogen-activated protein kinase-activated protein kinase 2 substrate: role in dimer formation and ligand bindingMAPKAPK-2 modulates p38-MAPK localization and small heat shock protein phosphorylation but does not mediate the injury associated with p38-MAPK activation during myocardial ischemia.Rational mutagenesis to support structure-based drug design: MAPKAP kinase 2 as a case study.p38 MAP kinase and MAPKAP kinases MK2/3 cooperatively phosphorylate epithelial keratinsPhosphorylation of tristetraprolin by MK2 impairs AU-rich element mRNA decay by preventing deadenylase recruitment.The stress-responsive kinases MAPKAPK2/MAPKAPK3 activate starvation-induced autophagy through Beclin 1 phosphorylationInhibition of p38 mitogen activated protein kinase controls airway inflammation in cystic fibrosisReactive Oxygen Species, SUMOylation, and Endothelial InflammationThe p38 MAPK-MK2 axis regulates E2F1 and FOXM1 expression after epirubicin treatment.Stress-induced phosphorylation of STAT1 at Ser727 requires p38 mitogen-activated protein kinase whereas IFN-gamma uses a different signaling pathway.Signaling by p38 MAPK stimulates nuclear localization of the microprocessor component p68 for processing of selected primary microRNAs.p53-deficient cells rely on ATM- and ATR-mediated checkpoint signaling through the p38MAPK/MK2 pathway for survival after DNA damage.p38 mitogen-activated protein kinase and mitogen-activated protein kinase-activated protein kinase 2 (MK2) signaling in atrophic and hypertrophic denervated mouse skeletal muscleQuantitative phosphoproteomic analysis of IL-33-mediated signalingNerve growth factor activates extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways to stimulate CREB serine 133 phosphorylation.Distinct cellular functions of MK2.Elimination of protein kinase MK5/PRAK activity by targeted homologous recombination.Identification of novel phosphorylation sites in MSK1 by precursor ion scanning MS.
P2860
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P2860
Constitutive activation of mitogen-activated protein kinase-activated protein kinase 2 by mutation of phosphorylation sites and an A-helix motif
description
1995 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1995
@ast
im November 1995 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1995/11/10)
@sk
vědecký článek publikovaný v roce 1995
@cs
wetenschappelijk artikel (gepubliceerd op 1995/11/10)
@nl
наукова стаття, опублікована в листопаді 1995
@uk
name
Constitutive activation of mit ...... ion sites and an A-helix motif
@ast
Constitutive activation of mit ...... ion sites and an A-helix motif
@en
Constitutive activation of mit ...... ion sites and an A-helix motif
@nl
type
label
Constitutive activation of mit ...... ion sites and an A-helix motif
@ast
Constitutive activation of mit ...... ion sites and an A-helix motif
@en
Constitutive activation of mit ...... ion sites and an A-helix motif
@nl
prefLabel
Constitutive activation of mit ...... ion sites and an A-helix motif
@ast
Constitutive activation of mit ...... ion sites and an A-helix motif
@en
Constitutive activation of mit ...... ion sites and an A-helix motif
@nl
P2093
P50
P356
P1476
Constitutive activation of mit ...... ion sites and an A-helix motif
@en
P2093
P304
27213–27221
P356
10.1074/JBC.270.45.27213
P407
P577
1995-11-10T00:00:00Z