Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication - sprookjes - yvandenbroek - TriplyDB

Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication

Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication

http://www.wikidata.org/entity/Q28611456

about

The retinoblastoma family of proteins and their regulatory functions in the mammalian cell division cycle Relationships between cancer and aging: a multilevel approach Temporal changes in rat liver gene expression after acute cadmium and chromium exposure Interferon Regulatory Factor 1 (IRF-1) induces p21(WAF1/CIP1) dependent cell cycle arrest and p21(WAF1/CIP1) independent modulation of survivin in cancer cells The cyclin-dependent kinase inhibitors p15INK4B and p21CIP1 are critical regulators of fibrillar collagen-induced tumor cell cycle arrest MCG10, a novel p53 target gene that encodes a KH domain RNA-binding protein, is capable of inducing apoptosis and cell cycle arrest in G(2)-M Retinoblastoma protein enhances the fidelity of chromosome segregation mediated by hsHec1p Mechanisms of G2 arrest in response to overexpression of p53 Kruppel-like factor 4 mediates p53-dependent G1/S cell cycle arrest in response to DNA damage BRCA1-associated growth arrest is RB-dependent Expression of cyclins A, E and topoisomerase II alpha correlates with centrosome amplification and genomic instability and influences the reliability of cytometric S-phase determination Examination of the expanding pathways for the regulation of p21 expression and activity.Targeting activating mutations of EZH2 leads to potent cell growth inhibition in human melanoma by derepression of tumor suppressor genes Understanding specific functions of PARP-2: new lessons for cancer therapy Peroxiredoxin 1 - an antioxidant enzyme in cancer A novel POK family transcription factor, ZBTB5, represses transcription of p21CIP1 gene A ribonucleotide reductase gene is a transcriptional target of p53 and p73 Cytokine response gene 6 induces p21 and regulates both cell growth and arrest Essential role of the CUL4B ubiquitin ligase in extra-embryonic tissue development during mouse embryogenesis Novel roles for p53 in the genesis and targeting of tetraploid cancer cells Expression of p21 and p53 in rat gingival and human oral epithelial cells after cyclosporine A treatment Growth retardation, polyploidy, and multinucleation induced by Clast3, a novel cell cycle-regulated protein ATM Signaling Pathway The N Terminus of the Retinoblastoma Protein Inhibits DNA Replication via a Bipartite Mechanism Disrupted in Partially Penetrant Retinoblastomas.p21 in cancer: intricate networks and multiple activities Aurora B kinase regulates the postmitotic endoreduplication checkpoint via phosphorylation of the retinoblastoma protein at serine 780 Udu deficiency activates DNA damage checkpoint.Simultaneous detection of cyclin B1, p105, and DNA content provides complete cell cycle phase fraction analysis of cells that endoreduplicate.In vivo cloning and characterization of a new growth suppressor protein TOE1 as a direct target gene of Egr1.A geminivirus replication protein interacts with a protein kinase and a motor protein that display different expression patterns during plant development and infection.ZBTB2, a novel master regulator of the p53 pathway.The N-terminal domain of the Drosophila retinoblastoma protein Rbf1 interacts with ORC and associates with chromatin in an E2F independent manner Chemopreventive agent 3,3'-diindolylmethane selectively induces proteasomal degradation of class I histone deacetylases.Anticarcinogenic effects of water extract of sporoderm-broken spores of Ganoderma lucidum on colorectal cancer in vitro and in vivo miR-375 activates p21 and suppresses telomerase activity by coordinately regulating HPV E6/E7, E6AP, CIP2A, and 14-3-3ζ cDNA microarray gene expression profiling of hedgehog signaling pathway inhibition in human colon cancer cells.Activation of extracellular signal-regulated kinase (ERK) in G2 phase delays mitotic entry through p21CIP1.p21WAF1/CIP1 gene transcriptional activation exerts cell growth inhibition and enhances chemosensitivity to cisplatin in lung carcinoma cell.The novel histone deacetylase inhibitor thailandepsin A inhibits anaplastic thyroid cancer growth.A human ribonuclease induces apoptosis associated with p21WAF1/CIP1 induction and JNK inactivation.

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Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication

http://www.wikidata.org/entity/Q28611456

description

1998 nî lūn-bûn

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1998 թուականի Յունուարին հրատարակուած գիտական յօդուած

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1998 թվականի հունվարին հրատարակված գիտական հոդված

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1998年の論文

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Effects of p21(Cip1/Waf1) at b ...... n preventing endoreduplication

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A B Niculescu

http://www.w3.org/2001/XMLSchema#string

C Prives

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L Hengst

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M Smeets

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S I Reed

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X Chen

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P2860

Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

Structural basis of cyclin-dependent kinase activation by phosphorylation

p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

Cyclin A is required at two points in the human cell cycle

Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex

Activation of cyclin E/CDK2 is coupled to site-specific autophosphorylation and ubiquitin-dependent degradation of cyclin E

Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6

Human cyclin E, a nuclear protein essential for the G1-to-S phase transition

Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex

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629-643

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2033675

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10.1128/MCB.18.1.629

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1

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18

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1998-01-01T00:00:00Z

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9418909

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121530

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