The human insulin receptor cDNA: the structural basis for hormone-activated transmembrane signalling
about
Landmarks in insulin researchCloning and characterization of a human ribosomal protein gene with enhanced expression in fetal and neoplastic cellsIsolation and chromosomal localization of the human fgr protooncogene, a distinct member of the tyrosine kinase gene familyActivation of the insulin receptor by insulin and a synthetic peptide leads to divergent metabolic and mitogenic signaling and responsesErythroid differentiation factor is encoded by the same mRNA as that of the inhibin beta A chainThe SPOT technique as a tool for studying protein tyrosine phosphatase substrate specificitiesaxl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinaseInteraction in vitro of the product of the c-Crk-II proto-oncogene with the insulin-like growth factor I receptorTwo novel protein-tyrosine kinases, each with a second phosphotransferase-related catalytic domain, define a new class of protein kinaseInteraction of p85 subunit of PI 3-kinase with insulin and IGF-1 receptors analysed by using the two-hybrid systemSH2-Balpha is an insulin-receptor adapter protein and substrate that interacts with the activation loop of the insulin-receptor kinaseTyrosine 740 phosphorylation of discoidin domain receptor 2 by Src stimulates intramolecular autophosphorylation and Shc signaling complex formationSequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptorsThe nucleotide sequence of the human int-1 mammary oncogene; evolutionary conservation of coding and non-coding sequencesHuman proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligandTwo additional protein-tyrosine kinases expressed in human lung: fourth member of the fibroblast growth factor receptor family and an intracellular protein-tyrosine kinaseTwo-subunit structure of the human thyrotropin receptorRYK, a receptor tyrosine kinase-related molecule with unusual kinase domain motifsThe integrity of the conserved 'WS motif' common to IL-2 and other cytokine receptors is essential for ligand binding and signal transductionCloning, sequencing, and chromosomal localization of human term placental alkaline phosphatase cDNAMolecular cloning of cDNAs of human liver and placenta NADH-cytochrome b5 reductaseHuman c-ros-1 gene homologous to the v-ros sequence of UR2 sarcoma virus encodes for a transmembrane receptorlike moleculeTwo putative protein-tyrosine kinases identified by application of the polymerase chain reactionCloning of a cDNA for steroid sulfatase: frequent occurrence of gene deletions in patients with recessive X chromosome-linked ichthyosisHuman placental Na+,K+-ATPase alpha subunit: cDNA cloning, tissue expression, DNA polymorphism, and chromosomal localizationMolecular cloning of syndecan, an integral membrane proteoglycanPost-transcriptional regulation in metabolic diseasesBravo/Nr-CAM is closely related to the cell adhesion molecules L1 and Ng-CAM and has a similar heterodimer structureCrystallographic and solution studies of an activation loop mutant of the insulin receptor tyrosine kinase: insights into kinase mechanismStructural and biochemical evidence for an autoinhibitory role for tyrosine 984 in the juxtamembrane region of the insulin receptorSolution structure of a conformationally restricted fully active derivative of the human relaxin-like factorCrystal structure of the tyrosine kinase domain of the human insulin receptorIGF-IR Targeted Therapy: Past, Present and FutureStructural variants of human T200 glycoprotein (leukocyte-common antigen)A B-lymphocyte activation molecule related to the nerve growth factor receptor and induced by cytokines in carcinomasCloning, sequence analysis and expression of a cDNA encoding a novel insulin-like growth factor binding protein (IGFBP-2)Interaction of insulin receptor substrate-2 (IRS-2) with the insulin and insulin-like growth factor I receptors. Evidence for two distinct phosphotyrosine-dependent interaction domains within IRS-2Interaction of MAD2 with the carboxyl terminus of the insulin receptor but not with the IGFIR. Evidence for release from the insulin receptor after activationAltered affinity of insulin-like growth factor II (IGF-II) for receptors and IGF-binding proteins, resulting from limited modifications of the IGF-II moleculeUptake and binding of radiolabelled phenylarsine oxide in 3T3-L1 adipocytes
P2860
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P2860
The human insulin receptor cDNA: the structural basis for hormone-activated transmembrane signalling
description
1985 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1985 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1985
@ast
im April 1985 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1985/04/01)
@sk
vědecký článek publikovaný v roce 1985
@cs
wetenschappelijk artikel (gepubliceerd op 1985/04/01)
@nl
наукова стаття, опублікована у квітні 1985
@uk
مقالة علمية (نشرت في أبريل 1985)
@ar
name
The human insulin receptor cDN ...... vated transmembrane signalling
@ast
The human insulin receptor cDN ...... vated transmembrane signalling
@en
The human insulin receptor cDN ...... vated transmembrane signalling
@nl
type
label
The human insulin receptor cDN ...... vated transmembrane signalling
@ast
The human insulin receptor cDN ...... vated transmembrane signalling
@en
The human insulin receptor cDN ...... vated transmembrane signalling
@nl
prefLabel
The human insulin receptor cDN ...... vated transmembrane signalling
@ast
The human insulin receptor cDN ...... vated transmembrane signalling
@en
The human insulin receptor cDN ...... vated transmembrane signalling
@nl
P2093
P3181
P1433
P1476
The human insulin receptor cDN ...... vated transmembrane signalling
@en
P2093
E. Clauser
F. Masiarz
I. D. Goldfine
K. Jarnagin
P304
P3181
P356
10.1016/0092-8674(85)90334-4
P407
P577
1985-04-01T00:00:00Z