The Jak kinases differentially associate with the alpha and beta (accessory factor) chains of the interferon gamma receptor to form a functional receptor unit capable of activating STAT transcription factors

The Jak kinases differentially associate with the alpha and beta (accessory factor) chains of the interferon gamma receptor to form a functional receptor unit capable of activating STAT transcription factors

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http://www.wikidata.org/entity/Q28646350

Q28646350

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Vaccinia virus blocks gamma interferon signal transduction: viral VH1 phosphatase reverses Stat1 activation Identification and functional characterization of a second chain of the interleukin-10 receptor complex.The Fanconi anemia protein FANCC binds to and facilitates the activation of STAT1 by gamma interferon and hematopoietic growth factors Kinase-negative mutants of JAK1 can sustain interferon-gamma-inducible gene expression but not an antiviral state N-formyl-methionyl-leucyl-phenylalanine inhibits both gamma interferon- and interleukin-10-induced expression of FcgammaRI on human monocytes Restoration of IFNγR subunit assembly, IFNγ signaling and parasite clearance in Leishmania donovani infected macrophages: role of membrane cholesterol Interferon gamma attenuates insulin signaling, lipid storage, and differentiation in human adipocytes via activation of the JAK/STAT pathway.The mEPN scheme: an intuitive and flexible graphical system for rendering biological pathways.Leishmania interferes with host cell signaling to devise a survival strategy.Biologic functions of the IFN-gamma receptors.A point mutation in a domain of gamma interferon receptor 1 provokes severe immunodeficiency.Anti-inflammatory cytokines in asthma and allergy: interleukin-10, interleukin-12, interferon-gamma.Protein expression, crystallization and preliminary X-ray crystallographic analysis of chicken interferon-γ receptor α chain.Targeted disruption of the interferon-gamma receptor 2 gene results in severe immune defects in mice.Human cytomegalovirus inhibits major histocompatibility complex class II expression by disruption of the Jak/Stat pathway.A JAK1/JAK2 chimera can sustain alpha and gamma interferon responses.Bordetella pertussis infection of primary human monocytes alters HLA-DR expression.Down-regulation of interferon gamma-activated STAT1 by UV light.Improving the spectral analysis of Fluorescence Resonance Energy Transfer in live cells: application to interferon receptors and Janus kinases.Evasion of Host Defence by Leishmania donovani: Subversion of Signaling Pathways.Metastatic melanoma cells evade immune detection by silencing STAT1.Cytokine research: the interferon paradigm.Ligand-induced assembly and activation of the gamma interferon receptor in intact cells.Down modulation of IFN-gamma signaling in alveolar macrophages isolated from smokers.Interaction of IFNG with IFNGR Dysregulation of the IFN-γ-STAT1 signaling pathway in a cell line model of large granular lymphocyte leukemia.

P2860

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P2860

The Jak kinases differentially associate with the alpha and beta (accessory factor) chains of the interferon gamma receptor to form a functional receptor unit capable of activating STAT transcription factors

Item

http://www.wikidata.org/entity/Q28646350

description

1995 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

1995 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

article publié dans la revue scientifique Journal of Biological Chemistry

@fr

artículu científicu espublizáu en 1995

@ast

im Juli 1995 veröffentlichter wissenschaftlicher Artikel

@de

scientific journal article

@en

vedecký článok (publikovaný 1995/07/21)

@sk

vědecký článek publikovaný v roce 1995

@cs

wetenschappelijk artikel (gepubliceerd op 1995/07/21)

@nl

наукова стаття, опублікована в липні 1995

@uk