Intrinsic conformational plasticity of native EmrE provides a pathway for multidrug resistance
about
Protonation of a glutamate residue modulates the dynamics of the drug transporter EmrENMR as a tool to investigate the structure, dynamics and function of membrane proteins.A structured loop modulates coupling between the substrate-binding and dimerization domains in the multidrug resistance transporter EmrE.Blocking dynamics of the SMR transporter EmrE impairs efflux activitySolid-state NMR and membrane proteins.Perplexing new insight into the dynamics of the EmrE transporter.Beyond Structural Biology to Functional Biology: Solid-State NMR Experiments and Strategies for Understanding the M2 Proton Channel Conductance.Protonation-dependent conformational dynamics of the multidrug transporter EmrE.Nuclear magnetic resonance (NMR) applied to membrane-protein complexes.Transmembrane Interactions of Full-length Mammalian Bitopic Cytochrome-P450-Cytochrome-b5 Complex in Lipid Bilayers Revealed by Sensitivity-Enhanced Dynamic Nuclear Polarization Solid-state NMR Spectroscopy.Functional response of the small multidrug resistance protein EmrE to mutations in transmembrane helix 2.NMR Spectroscopy Approach to Study the Structure, Orientation, and Mechanism of the Multidrug Exporter EmrE.New free-exchange model of EmrE transport.A suite of pulse sequences based on multiple sequential acquisitions at one and two radiofrequency channels for solid-state magic-angle spinning NMR studies of proteins.Guanidinium export is the primal function of SMR family transporters.Magnetically Alignable Bicelles with Unprecedented Stability Using Tunable Surfactants Derived from Cholic Acid.Chemically Locked Bicelles with High Thermal and Kinetic Stability.Influence of quaternary cation compound on the size of the Escherichia coli small multidrug resistance protein, EmrE.Small Multidrug Resistance Efflux Pumps
P2860
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P2860
Intrinsic conformational plasticity of native EmrE provides a pathway for multidrug resistance
description
2014 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2014
@ast
im Juni 2014 veröffentlichter wissenschaftlicher Artikel
@de
scientific article (publication date: 4 June 2014)
@en
vedecký článok (publikovaný 2014/06/04)
@sk
vědecký článek publikovaný v roce 2014
@cs
wetenschappelijk artikel (gepubliceerd op 2014/06/04)
@nl
наукова стаття, опублікована в червні 2014
@uk
مقالة علمية (نشرت في 4-6-2014)
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name
Intrinsic conformational plast ...... thway for multidrug resistance
@ast
Intrinsic conformational plast ...... thway for multidrug resistance
@en
Intrinsic conformational plast ...... thway for multidrug resistance
@nl
type
label
Intrinsic conformational plast ...... thway for multidrug resistance
@ast
Intrinsic conformational plast ...... thway for multidrug resistance
@en
Intrinsic conformational plast ...... thway for multidrug resistance
@nl
prefLabel
Intrinsic conformational plast ...... thway for multidrug resistance
@ast
Intrinsic conformational plast ...... thway for multidrug resistance
@en
Intrinsic conformational plast ...... thway for multidrug resistance
@nl
P2093
P2860
P356
P1476
Intrinsic conformational plast ...... thway for multidrug resistance
@en
P2093
Anindita Gayen
Maureen Leninger
Nathaniel J Traaseth
P2860
P304
P356
10.1021/JA503145X
P407
P577
2014-05-23T00:00:00Z