Transcriptional profiling of human brain endothelial cells reveals key properties crucial for predictive in vitro blood-brain barrier models
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Cell-culture models of the blood-brain barrierBiphasic mechanisms of neurovascular unit injury and protection in CNS diseasesDevelopment, maintenance and disruption of the blood-brain barrierPathogens penetrating the central nervous system: infection pathways and the cellular and molecular mechanisms of invasionCombinatorial approaches for the identification of brain drug delivery targets.The Metalloprotease, Mpr1, Engages AnnexinA2 to Promote the Transcytosis of Fungal Cells across the Blood-Brain Barrier.Dissecting gene expression at the blood-brain barrierThe Sarcoglycan complex is expressed in the cerebrovascular system and is specifically regulated by astroglial Cx30 channels.Human severe sepsis cytokine mixture increases β2-integrin-dependent polymorphonuclear leukocyte adhesion to cerebral microvascular endothelial cells in vitro.Blood-brain barrier endogenous transporters as therapeutic targets: a new model for small molecule CNS drug discovery.Prolonged Morphine Exposure Induces Increased Firm Adhesion in an in Vitro Model of the Blood-Brain BarrierThe hCMEC/D3 cell line as a model of the human blood brain barrier.Targeting ApoE4/ApoE receptor LRP1 in Alzheimer's disease.A Three-Dimensional Cell Culture System To Model RNA Virus Infections at the Blood-Brain BarrierBlood-brain barrier models: in vitro to in vivo translation in preclinical development of CNS-targeting biotherapeutics.BBBomics-Human Blood Brain Barrier Transcriptomics Hub.Glucose Transporters at the Blood-Brain Barrier: Function, Regulation and Gateways for Drug Delivery.In vitro models of the blood-brain barrier: An overview of commonly used brain endothelial cell culture models and guidelines for their use.Vectorized nanodelivery systems for ischemic stroke: a concept and a need.Limitations of the hCMEC/D3 cell line as a model for Aβ clearance by the human blood-brain barrier.Co-culture model consisting of human brain microvascular endothelial and peripheral blood mononuclear cells.Mechanisms of cellular plasticity in cerebral perivascular region.Re-engineering therapeutic antibodies for Alzheimer's disease as blood-brain barrier penetrating bi-specific antibodies.New experimental models of the blood-brain barrier for CNS drug discovery.Cytokine-induced changes in the gene expression profile of a human cerebral microvascular endothelial cell-line, hCMEC/D3Cryptococcus neoformans promotes its transmigration into the central nervous system by inducing molecular and cellular changes in brain endothelial cellsMulticellular self-assembled spheroidal model of the blood brain barrier.TSPO imaging using the novel PET ligand [18F]GE-180: quantification approaches in patients with multiple sclerosis.Isolation and Culture of Brain Microvascular Endothelial Cells for In Vitro Blood-Brain Barrier Studies.Blood-brain barrier-on-a-chip: Microphysiological systems that capture the complexity of the blood-central nervous system interface.Effects of insulin combined with idebenone on blood-brain barrier permeability in diabetic rats.Development of a direct contact astrocyte-human cerebral microvessel endothelial cells blood-brain barrier coculture model.Comparison of a Rat Primary Cell-Based Blood-Brain Barrier Model With Epithelial and Brain Endothelial Cell Lines: Gene Expression and Drug Transport.Differential chemokine expression under the control of peripheral blood mononuclear cells issued from Alzheimer's patients in a human blood brain barrier model
P2860
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P2860
Transcriptional profiling of human brain endothelial cells reveals key properties crucial for predictive in vitro blood-brain barrier models
description
2012 nî lūn-bûn
@nan
2012 թուականին հրատարակուած գիտական յօդուած
@hyw
2012 թվականին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Transcriptional profiling of h ...... tro blood-brain barrier models
@ast
Transcriptional profiling of h ...... tro blood-brain barrier models
@en
Transcriptional profiling of h ...... tro blood-brain barrier models
@nl
type
label
Transcriptional profiling of h ...... tro blood-brain barrier models
@ast
Transcriptional profiling of h ...... tro blood-brain barrier models
@en
Transcriptional profiling of h ...... tro blood-brain barrier models
@nl
prefLabel
Transcriptional profiling of h ...... tro blood-brain barrier models
@ast
Transcriptional profiling of h ...... tro blood-brain barrier models
@en
Transcriptional profiling of h ...... tro blood-brain barrier models
@nl
P2093
P2860
P921
P3181
P1433
P1476
Transcriptional profiling of h ...... tro blood-brain barrier models
@en
P2093
Eduard Urich
Isabelle Wells
Juliette Molnos
Per-Ola Freskgård
Stanley E Lazic
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0038149
P407
P577
2012-01-01T00:00:00Z