Silylation of C–H bonds in aromatic heterocycles by an Earth-abundant metal catalyst
about
Evaluating New Chemistry to Drive Molecular Discovery: Fit for Purpose?Radicals: Reactive Intermediates with Translational PotentialChemoselective single-site Earth-abundant metal catalysts at metal-organic framework nodesCatalytic C-H bond silylation of aromatic heterocycles.Ru-catalysed C-H silylation of unprotected gramines, tryptamines and their congeners.Trifluoromethylation of Arylsilanes with [(phen)CuCF3 ]Catalytic Reductive ortho-C-H Silylation of Phenols with Traceless, Versatile Acetal Directing Groups and Synthetic Applications of DioxasilinesRecent developments in free-radical-promoted C-Si formation via selective C-H/Si-H functionalization.Accessing Drug Metabolites via Transition-Metal Catalyzed C-H Oxidation: The Liver as Synthetic Inspiration.A Mild and General Larock Indolization Protocol for the Preparation of Unnatural Tryptophans.A well-defined NHC-Ir(iii) catalyst for the silylation of aromatic C-H bonds: substrate survey and mechanistic insights.Electron-Transfer and Hydride-Transfer Pathways in the Stoltz-Grubbs Reducing System (KOtBu/Et3 SiH).Directed evolution of cytochrome c for carbon-silicon bond formation: Bringing silicon to life.Palladium(II)-catalyzed allylic C-H oxidation of hindered substrates featuring tunable selectivity over extent of oxidation.Nickel-catalysed direct alkylation of thiophenes via double C(sp3)-H/C(sp2)-H bond cleavage: the importance of KH2PO4.Rhodium-Catalyzed Intramolecular C-H Silylation by Silacyclobutanes.Nickel-Catalyzed Cross-Coupling of Organolithium Reagents with (Hetero)Aryl Electrophiles.Ir-Catalyzed Enantioselective, Intramolecular Silylation of Methyl C-H Bonds.Transition-Metal-Free Ring-Opening Silylation of Indoles and Benzofurans with (Diphenyl-tert-butylsilyl)lithium.Iron-Catalyzed Intermolecular 1,2-Difunctionalization of Styrenes and Conjugated Alkenes with Silanes and Nucleophiles.Metal-Free Arene and Heteroarene Borylation Catalyzed by Strongly Electrophilic Bis-boranes.t-BuONa-mediated direct C-H halogenation of electron-deficient (hetero)arenes.Friedel-Crafts-Type Intermolecular C-H Silylation of Electron-Rich Arenes Initiated by Base-Metal Salts.Silver(i)-promoted insertion into X-H (X = Si, Sn, and Ge) bonds with N-nosylhydrazones.CO2 Conversion into Esters by Fluoride-Mediated Carboxylation of Organosilanes and Halide Derivatives.HMPA-Promoted Siladifluoromethylation of Di-, and Triarylmethanes with the Ruppert-Prakash Reagent.Chemoselective and Catalyst-Free O-Borylation of Silanols: A Facile Access to Borasiloxanes.Rhodium-Catalyzed Silylative and Germylative Cyclization with Dehydrogenation Leading to 9-Sila- and 9-Germafluorenes: A Combined Experimental and Computational Mechanistic Study.Oxidative radical divergent Si-incorporation: facile access to Si-containing heterocycles.Imidazole synthesis by transition metal free, base-mediated deaminative coupling of benzylamines and nitriles.Palladium-catalyzed direct sulfonylation of C-H bonds with the insertion of sulfur dioxide.Silylations of Arenes with Hydrosilanes: From Transition-Metal-Catalyzed C¢X Bond Cleavage to Environmentally Benign Transition-Metal-Free C¢H Bond Activation.Unexpectedly Simple Synthesis of Benzazoles by tBuONa-Catalyzed Direct Aerobic Oxidative Cyclocondensation of o-Thio/Hydroxy/Aminoanilines with Alcohols under Air.Approach for 2-(arylthio)imidazoles and imidazo[2,1-b]thiazoles from imidazo[2,1-b][1,3,4]thiadiazoles by ring-opening and -reconstruction.Catalytic Electrophilic C-H Silylation of Pyridines Enabled by Temporary Dearomatization.Nickel-catalyzed borylation of arenes and indoles via C-H bond cleavage.Catalytic activation of a single C-F bond in trifluoromethyl arenes.Reagent-controlled regiodivergent intermolecular cyclization of 2-aminobenzothiazoles with β-ketoesters and β-ketoamides.Evaluierung neuer Reaktionen zur Steuerung der Wirkstoff-Forschung: ein EignungstestDefluorosilylation of fluoroarenes and fluoroalkanes
P2860
Q28066537-1E262F7B-584D-4A43-BC56-0BD09ACDAAD1Q28468198-9C0575F0-EBB6-4467-9B18-000C6850201EQ28831155-83771077-92F9-4D46-90E0-4E588DDAAF9DQ35826313-60C2FA4C-EEB2-4F9C-8161-8081663F563FQ35981283-1F1734E2-B58E-4A5E-A20D-62678EA58C41Q37158035-5B8F42DD-FFFB-4092-AA86-977EB06EA9DBQ37406215-47EC30F9-879A-4203-8874-CB279848A497Q38893722-AE3A983A-9151-4805-8E09-F9646EC4808EQ38977018-BB74BEBD-5340-434D-A73D-CB4F093EB934Q40980510-4CA6E235-C25C-469F-A591-D4F21F788327Q41671204-7AECBEE4-EF8F-4142-82B9-6FAB447858AFQ43095184-4506C116-105D-4AF8-BBBA-F6EA08F4C242Q45944225-08E361F5-60FA-41CD-941B-7AFC624E17D8Q46166755-380F88B1-0338-47A0-A6F4-9308ED42B347Q46339290-78B5FABA-3B33-443D-BD7B-B59CA8197D6CQ46564479-A9ED6256-6325-4A37-A1BD-3F12DAF1528CQ46617930-61B3F16A-C70B-4875-A286-1AA89B2F820BQ46904625-37593FBB-0633-4EE3-B2A4-E4A9EAD52DD1Q48103271-16029C8C-AE0C-4B04-BE66-C9D2A5774607Q48165406-2C946816-2684-48D6-8FB4-3238457424E2Q48224293-6CC2040B-2079-4D8C-A807-2255E550C0F1Q48230890-A6D2AF8F-A474-44AA-A3A1-7CD865A49367Q48251865-F3D4DACD-FDFC-4A90-9E21-1EE9F2C9633AQ48254615-FFE40B12-07D7-420A-B9BF-FAE53E43992FQ48273272-ABDD3E43-2A38-4FCF-940A-8F987981F452Q48302217-A3DA507B-640B-4843-84E1-D6DD12C9C3BBQ48338145-E49CB534-A92C-48AB-9AA5-EA788FFED2AEQ48359728-585AACD2-7EEA-4861-8337-6A1E108F4E15Q48540229-12FA612D-F4B7-4AC8-BB08-1CE166F8AFF8Q48592111-E7543DB8-1607-42C4-A55F-937268B8A521Q50122874-A272FDAA-A85C-4334-8797-0446F6181A25Q50267622-6A084CBB-53EB-479E-A587-134CA73C719BQ50269480-18E79820-4432-4467-9779-7BF8E56EE0E0Q51519628-D5EBF375-9E57-48C0-B06C-3DA37EB78992Q52860220-2987D157-5057-476A-9469-33FDC9EECFA0Q52958527-937B05DC-9413-460D-8B07-C812A4A6FC70Q55314549-47543582-0A22-4D2B-9180-7F79A5DB1A13Q55618841-45DE5B8A-70EE-4162-A976-901624EF1A8EQ56329923-7EA5A61A-D018-4501-9601-AF0D99024D6BQ57804760-9D14A995-A1E2-4469-95FB-83998346041A
P2860
Silylation of C–H bonds in aromatic heterocycles by an Earth-abundant metal catalyst
description
2015 nî lūn-bûn
@nan
2015 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Silylation of C–H bonds in aromatic heterocycles by an Earth-abundant metal catalyst
@ast
Silylation of C–H bonds in aromatic heterocycles by an Earth-abundant metal catalyst
@en
type
label
Silylation of C–H bonds in aromatic heterocycles by an Earth-abundant metal catalyst
@ast
Silylation of C–H bonds in aromatic heterocycles by an Earth-abundant metal catalyst
@en
prefLabel
Silylation of C–H bonds in aromatic heterocycles by an Earth-abundant metal catalyst
@ast
Silylation of C–H bonds in aromatic heterocycles by an Earth-abundant metal catalyst
@en
P2093
P3181
P356
P1433
P1476
Silylation of C–H bonds in aromatic heterocycles by an Earth-abundant metal catalyst
@en
P2093
Anton A. Toutov
Brian M. Stoltz
Kerry N. Betz
Wen-Bo Liu
P2888
P3181
P356
10.1038/NATURE14126
P407
P577
2015-02-04T00:00:00Z
P6179
1036785057