Targeted gene addition to a predetermined site in the human genome using a ZFN-based nicking enzyme - sprookjes - yvandenbroek - TriplyDB

Targeted gene addition to a predetermined site in the human genome using a ZFN-based nicking enzyme

Targeted gene addition to a predetermined site in the human genome using a ZFN-based nicking enzyme

http://www.wikidata.org/entity/Q29308378

about

Optimising homing endonuclease gene drive performance in a semi-refractory species: the Drosophila melanogaster experience What does our genome encode?Cas9 as a versatile tool for engineering biology Nuclease Target Site Selection for Maximizing On-target Activity and Minimizing Off-target Effects in Genome Editing Minimizing off-Target Mutagenesis Risks Caused by Programmable Nucleases Enabling functional genomics with genome engineering Engineering large animal models of human disease Designed nucleases for targeted genome editing Progress and Prospects of Anti-HBV Gene Therapy Development Synthetic biology and therapeutic strategies for the degenerating brain: Synthetic biology approaches can transform classical cell and gene therapies, to provide new cures for neurodegenerative diseases Repair of strand breaks by homologous recombination Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering CRISPR-Cas systems for editing, regulating and targeting genomes Type II restriction endonucleases--a historical perspective and more Random mutagenesis analysis and identification of a novel C2H2-type transcription factor from the nematode-trapping fungus Arthrobotrys oligospora.The scientific quest for lasting youth: prospects for curing aging.TALE nickase-mediated SP110 knockin endows cattle with increased resistance to tuberculosis.TRACER: a resource to study the regulatory architecture of the mouse genome Stem cells on the brain: modeling neurodevelopmental and neurodegenerative diseases using human induced pluripotent stem cells.To nick or not to nick: comparison of I-SceI single- and double-strand break-induced recombination in yeast and human cells.Determining the specificities of TALENs, Cas9, and other genome-editing enzymes Precision genome engineering with programmable DNA-nicking enzymes.EENdb: a database and knowledge base of ZFNs and TALENs for endonuclease engineering TALENs: a widely applicable technology for targeted genome editing.Generation of TALE nickase-mediated gene-targeted cows expressing human serum albumin in mammary glands.Genome engineering: Drosophila melanogaster and beyond Genome Engineering Using Adeno-associated Virus: Basic and Clinical Research Applications.Homology-driven genome editing in hematopoietic stem and progenitor cells using ZFN mRNA and AAV6 donors.Zinc-finger nickase-mediated insertion of the lysostaphin gene into the beta-casein locus in cloned cows.Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases.A cut above the rest: targeted genome editing technologies in human pluripotent stem cells.The Development of TALE Nucleases for Biotechnology.Evaluation of novel design strategies for developing zinc finger nucleases tools for treating human diseases.Advances in targeted genome editing.Emerging tools for synthetic genome design Genetic analysis of type 1 diabetes: embryonic stem cells as new tools to unlock biological mechanisms in type 1 diabetes.Nuclease-mediated genome editing: At the front-line of functional genomics technology.A guide to genome engineering with programmable nucleases.Emerging gene editing strategies for Duchenne muscular dystrophy targeting stem cells.

P2860

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P2860

Targeted gene addition to a predetermined site in the human genome using a ZFN-based nicking enzyme

http://www.wikidata.org/entity/Q29308378

description

2012 nî lūn-bûn

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2012 թուականի Մարտին հրատարակուած գիտական յօդուած

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2012 թվականի մարտին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

Targeted gene addition to a pr ...... ing a ZFN-based nicking enzyme

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Targeted gene addition to a pr ...... ing a ZFN-based nicking enzyme

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Genome Research

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Targeted gene addition to a pr ...... ing a ZFN-based nicking enzyme

@en

P2093

Carrie Jiaxin Li

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Geoffrey Friedman

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Jeffrey C Miller

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Jenny Jiacheng Yan

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Jianbin Wang

http://www.w3.org/2001/XMLSchema#string

Joshua E Babiarz

http://www.w3.org/2001/XMLSchema#string

Michael C Holmes

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Nathaniel S Wang

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P2860

Homologous Pairing and Strand Exchange in Genetic Recombination

Historical overview: searching for replication help in all of the rec places

Knockout rats via embryo microinjection of zinc-finger nucleases

Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases

Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae

Progress and prospects: zinc-finger nucleases as gene therapy agents

Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification

Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases

High-frequency modification of plant genes using engineered zinc-finger nucleases

FokI dimerization is required for DNA cleavage

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1316-1326

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scholarly article

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5126108

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10.1101/GR.122879.111

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7

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22

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Philip D Gregory

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2012-03-20T00:00:00Z

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221877941

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22434427

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3396372

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