Circumventing the Crabtree Effect: Replacing Media Glucose with Galactose Increases Susceptibility of HepG2 Cells to Mitochondrial Toxicants
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Overexpression of DNA ligase III in mitochondria protects cells against oxidative stress and improves mitochondrial DNA base excision repairMitochondrial pyrimidine nucleotide carrier (PNC1) regulates mitochondrial biogenesis and the invasive phenotype of cancer cellsShort-term calorie restriction enhances skeletal muscle stem cell functionAn ISA-TAB-Nano based data collection framework to support data-driven modelling of nanotoxicologyThe HK2 Dependent "Warburg Effect" and Mitochondrial Oxidative Phosphorylation in Cancer: Targets for Effective Therapy with 3-BromopyruvateKey Challenges and Opportunities Associated with the Use of In Vitro Models to Detect Human DILI: Integrated Risk Assessment and Mitigation PlansThe Warburg effect: 80 years onThe mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistanceA mitochondrial RNAi screen defines cellular bioenergetic determinants and identifies an adenylate kinase as a key regulator of ATP levelsDoxorubicin in vivo rapidly alters expression and translation of myocardial electron transport chain genes, leads to ATP loss and caspase 3 activationA high-throughput screen for mitochondrial function reveals known and novel mitochondrial toxicants in a library of environmental agentsPolymorphisms in the mitochondrial ribosome recycling factor EF-G2mt/MEF2 compromise cell respiratory function and increase atorvastatin toxicityDifferential mitochondrial toxicity screening and multi-parametric data analysisSensitivity of mitochondrial transcription and resistance of RNA polymerase II dependent nuclear transcription to antiviral ribonucleosidesCisplatin induces a mitochondrial-ROS response that contributes to cytotoxicity depending on mitochondrial redox status and bioenergetic functionsModulators of hepatic lipoprotein metabolism identified in a search for small-molecule inducers of tribbles pseudokinase 1 expressionAssessment of ToxCast Phase II for Mitochondrial Liabilities Using a High-Throughput Respirometric AssayThe Eye Drop Preservative Benzalkonium Chloride Potently Induces Mitochondrial Dysfunction and Preferentially Affects LHON Mutant CellsAttenuation of noise-induced hearing loss using methylene blue.Bafilomycin A1 activates respiration of neuronal cells via uncoupling associated with flickering depolarization of mitochondriaA tail-anchored myotonic dystrophy protein kinase isoform induces perinuclear clustering of mitochondria, autophagy, and apoptosisADDME--Avoiding Drug Development Mistakes Early: central nervous system drug discovery perspectiveGlucose controls morphodynamics of LPS-stimulated macrophages.Differential Mitochondrial Requirements for Radially and Non-radially Migrating Cortical Neurons: Implications for Mitochondrial Disorders.Modulation of oxidative phosphorylation and redox homeostasis in mitochondrial NDUFS4 deficiency via mesenchymal stem cells.Galactose enhances oxidative metabolism and reveals mitochondrial dysfunction in human primary muscle cellsSystematic study of mitochondrial toxicity of environmental chemicals using quantitative high throughput screening.Impaired mitochondrial function in human placenta with increased maternal adiposityMechanisms by which low glucose enhances the cytotoxicity of metformin to cancer cells both in vitro and in vivo.Membrane-bound CYB5R3 is a common effector of nutritional and oxidative stress response through FOXO3a and Nrf2.Quinolone-3-diarylethers: a new class of antimalarial drug.Efavirenz induces neuronal autophagy and mitochondrial alterations.Identification of the Additional Mitochondrial Liabilities of 2-Hydroxyflutamide When Compared With its Parent Compound, Flutamide in HepG2 Cells.Respiratory flexibility in response to inhibition of cytochrome C oxidase in Mycobacterium tuberculosis.Remodeling of oxidative energy metabolism by galactose improves glucose handling and metabolic switching in human skeletal muscle cells.SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilizationHigh-throughput respirometric assay identifies predictive toxicophore of mitochondrial injury.Lithium induces ER stress and N-glycan modification in galactose-grown Jurkat cells.Low glucose but not galactose enhances oxidative mitochondrial metabolism in C2C12 myoblasts and myotubes.Identification of fumarate hydratase inhibitors with nutrient-dependent cytotoxicity.
P2860
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P2860
Circumventing the Crabtree Effect: Replacing Media Glucose with Galactose Increases Susceptibility of HepG2 Cells to Mitochondrial Toxicants
description
2007 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2007
@ast
im Januar 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific article (publication date: 18 January 2007)
@en
wetenschappelijk artikel (gepubliceerd op 2007/01/18)
@nl
наукова стаття, опублікована в січні 2007
@uk
مقالة علمية (نشرت في 18-1-2007)
@ar
name
Circumventing the Crabtree Eff ...... lls to Mitochondrial Toxicants
@ast
Circumventing the Crabtree Eff ...... lls to Mitochondrial Toxicants
@en
type
label
Circumventing the Crabtree Eff ...... lls to Mitochondrial Toxicants
@ast
Circumventing the Crabtree Eff ...... lls to Mitochondrial Toxicants
@en
prefLabel
Circumventing the Crabtree Eff ...... lls to Mitochondrial Toxicants
@ast
Circumventing the Crabtree Eff ...... lls to Mitochondrial Toxicants
@en
P2093
P921
P3181
P356
P1476
Circumventing the Crabtree Eff ...... lls to Mitochondrial Toxicants
@en
P2093
J. A. Dykens
J. D. Jamieson
L. D. Marroquin
P304
P3181
P356
10.1093/TOXSCI/KFM052
P577
2007-01-18T00:00:00Z