A chemical switch for inhibitor-sensitive alleles of any protein kinase
about
An overview of Cdk1-controlled targets and processesCrystal structure of the Golgi casein kinaseThe regulated assembly of a PKCepsilon complex controls the completion of cytokinesisFinding new components of the target of rapamycin (TOR) signaling network through chemical genetics and proteome chipsCDK targets Sae2 to control DNA-end resection and homologous recombinationEGFR phosphorylates tumor-derived EGFRvIII driving STAT3/5 and progression in glioblastomaThe chemical biology of protein phosphorylationFunctional organization of the S. cerevisiae phosphorylation networkPil1 controls eisosome biogenesis.The selectivity of protein kinase inhibitors: a further updateChemical genomics: what will it take and who gets to play?An unbiased cell morphology-based screen for new, biologically active small moleculesApplications of small molecule probes in dissecting mechanisms of bacterial virulence and host responsesThe final link: tapping the power of chemical genetics to connect the molecular and biologic functions of mitotic protein kinasesStatus of large-scale analysis of post-translational modifications by mass spectrometryAn unexpected journey: lysine methylation across the proteomeHigh-throughput microfluidics to control and measure signaling dynamics in single yeast cells.The Functional Significance of Posttranslational Modifications on Polo-Like Kinase 1 Revealed by Chemical Genetic ComplementationPKA antagonizes CLASP-dependent microtubule stabilization to re-localize Pom1 and buffer cell size upon glucose limitationIpl1/Aurora kinase suppresses S-CDK-driven spindle formation during prophase I to ensure chromosome integrity during meiosisStructure and Substrate Recruitment of the Human Spindle Checkpoint Kinase Bub1Toxoplasma gondii calcium-dependent protein kinase 1 is a target for selective kinase inhibitorsDiscovery of Potent and Selective Inhibitors of CDPK1 from C. parvum and T. gondiiChemical genetic strategy for targeting protein kinases based on covalent complementarityMultiple Determinants for Selective Inhibition of Apicomplexan Calcium-Dependent Protein Kinase CDPK1Structure-guided optimization of protein kinase inhibitors reverses aminoglycoside antibiotic resistanceStructure-Guided Inhibitor Design Expands the Scope of Analog-Sensitive Kinase TechnologyStaurosporine-Derived Inhibitors Broaden the Scope of Analog-Sensitive Kinase TechnologyHrr25/CK1δ-directed release of Ltv1 from pre-40S ribosomes is necessary for ribosome assembly and cell growthPhosphorylation of the RNA polymerase II C-terminal domain by TFIIH kinase is not essential for transcription of Saccharomyces cerevisiae genomeCell cycle-dependent regulation of Saccharomyces cerevisiae donor preference during mating-type switching by SBF (Swi4/Swi6) and Fkh1.Distinct mechanisms control the stability of the related S-phase cyclins Clb5 and Clb6.Inhibition of the mitotic exit network in response to damaged telomeres.Mps1 kinase promotes sister-kinetochore bi-orientation by a tension-dependent mechanismActivation of the Cdc42p GTPase by cyclin-dependent protein kinases in budding yeast.Cell cycle-dependent nuclear export of Cdh1p may contribute to the inactivation of APC/C(Cdh1)The Saccharomyces cerevisiae Mob2p-Cbk1p kinase complex promotes polarized growth and acts with the mitotic exit network to facilitate daughter cell-specific localization of Ace2p transcription factorCyclin-dependent kinase directly regulates initiation of meiotic recombinationA mechanism for the coordination of proliferation and differentiation by spatial regulation of Fus2p in budding yeast.Two cyclin-dependent kinases promote RNA polymerase II transcription and formation of the scaffold complex.
P2860
Q21203553-4CEC8720-01AB-4016-BE33-41463E035DEFQ24294846-6165C261-B685-4BCA-918E-A880401ACAD3Q24310255-F2C87358-46D9-4236-AC6E-5E85E9BFCA4BQ24314346-49BF45E1-4EB3-4EDA-B3E5-73B52D49E32EQ24328867-9216F4C6-0D9C-4974-9EEC-EA54423F9E33Q24338526-2B107852-2103-4E8D-B8FE-57D165173F9AQ24620636-D96DABC1-0211-434F-BA84-315F4E00D199Q24634340-D32555AF-9E1F-4E35-8E4D-A7D5671FE0EFQ24642437-8C2A78E2-C0F5-401B-8E74-CBF17E28FC58Q24654622-BE45E7C7-DDFC-4AEC-88A5-485E583D40F7Q24805615-72C4D89B-C314-419C-AF22-C6D720A3A561Q24806083-791D6EAD-F199-4E1C-A05A-B1F6FFAC2761Q26822978-4C112860-6007-432B-B868-274ECAA39470Q26823414-AA26FA97-B94F-411A-AEE7-966DFC3C3C47Q26829144-1A01D1EB-5282-4DE3-B248-6832885EEB64Q26864659-6A2DD5D9-3C06-47EC-B06C-A2343D81CC2EQ27310343-FF7B920B-FE6E-43DD-A7F9-1A2242CB93C9Q27320051-02C704AF-5AA7-4382-9B2F-69FF06693BE1Q27322471-F35DF2F3-8809-4CF7-BD12-9DBA7AB7EFB5Q27336045-D34FA7F7-A2FF-49FF-B7CA-2BF5CD978507Q27652822-1FA896A7-03A7-4A22-8A9A-C64566A6A786Q27661190-B0DEA568-621A-47DC-A0F1-916C9914EB02Q27666106-FE43C4B2-2EC7-4EBF-B793-FAACC01E89D0Q27671824-2C16D072-D198-4143-AAF8-5C6BEE869854Q27677507-22FE0975-BDC4-42B3-A796-417F096E55F3Q27678586-8F7871B6-2E6F-42B3-81BD-0723432F12E5Q27679025-8B701218-7171-4B3C-BDEE-4CC3483E62CAQ27680486-A89E07EF-4AE5-46B2-8F90-B9DF913947FAQ27930417-E9F1280D-75FF-4FE7-89AF-1FB969524BC5Q27930453-35643D21-595D-4834-9E88-832C8FAC4A92Q27930742-0EE94DC5-02E1-4555-9BD4-3E50D8568CDBQ27930748-DB892EB1-AF29-4A8B-A12E-D7D9F5F03971Q27930771-D19AEE7D-5E95-4216-AA35-7B98BE0E1E0FQ27930787-C8044A59-D03C-4C3E-A20F-AC608C386DBAQ27932231-8171189C-FD23-4B30-A39B-E383EF5A37A9Q27932430-C0641761-35EB-411F-80E1-888CEC5287E4Q27932966-79D33B5F-BD42-45E1-AE55-21D4162B5718Q27933030-31E0D455-E55F-40C9-A9E8-FD2AC53453A5Q27933058-7BF87884-A707-4A2C-BBF8-1DF9D995C46BQ27933162-CCAB8908-4C35-4A9D-B856-EA50B598C171
P2860
A chemical switch for inhibitor-sensitive alleles of any protein kinase
description
2000 nî lūn-bûn
@nan
2000 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
A chemical switch for inhibitor-sensitive alleles of any protein kinase
@ast
A chemical switch for inhibitor-sensitive alleles of any protein kinase
@en
type
label
A chemical switch for inhibitor-sensitive alleles of any protein kinase
@ast
A chemical switch for inhibitor-sensitive alleles of any protein kinase
@en
prefLabel
A chemical switch for inhibitor-sensitive alleles of any protein kinase
@ast
A chemical switch for inhibitor-sensitive alleles of any protein kinase
@en
P2093
P3181
P356
P1433
P1476
A chemical switch for inhibitor-sensitive alleles of any protein kinase
@en
P2093
Blethrow J
Matheos DP
Schultz PG
P2888
P304
P3181
P356
10.1038/35030148
P407
P577
2000-09-21T00:00:00Z
P6179
1007129994