Natural selection on protein-coding genes in the human genome
about
The evolution of mammalian gene familiesIdentification of the imprinted KLF14 transcription factor undergoing human-specific accelerated evolutionMultiple advantageous amino acid variants in the NAT2 gene in human populationsThe role of geography in human adaptationGene regulation in primates evolves under tissue-specific selection pressuresGenetic variation in an individual human exomePatterns of positive selection in six Mammalian genomesLocalizing recent adaptive evolution in the human genomeHotspots of biased nucleotide substitutions in human genesComparative analysis of function and interaction of transcription factors in nematodes: extensive conservation of orthology coupled to rapid sequence evolutionPrevalence of positive selection among nearly neutral amino acid replacements in DrosophilaAn integrated view of protein evolutionThe CD300a (IRp60) inhibitory receptor is rapidly up-regulated on human neutrophils in response to inflammatory stimuli and modulates CD32a (FcgammaRIIa) mediated signalingDeciphering the ancient and complex evolutionary history of human arylamine N-acetyltransferase genes.Novel genes derived from noncoding DNA in Drosophila melanogaster are frequently X-linked and exhibit testis-biased expressionHuman brain evolution: from gene discovery to phenotype discoveryA systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardationWhy time matters: codon evolution and the temporal dynamics of dN/dSHuman-specific loss of regulatory DNA and the evolution of human-specific traitsRecent acceleration of human adaptive evolutionA second generation human haplotype map of over 3.1 million SNPsGlobal analysis of alternative splicing differences between humans and chimpanzeesA large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genesStrong purifying selection at synonymous sites in D. melanogasterGenes involved in complex adaptive processes tend to have highly conserved upstream regions in mammalian genomes.Dry and wet approaches for genome-wide functional annotation of conventional and unconventional transcriptional activatorsThe Impact of Evolutionary Driving Forces on Human Complex Diseases: A Population Genetics ApproachFifteen years of genomewide scans for selection: trends, lessons and unaddressed genetic sources of complicationGenetics of autoimmune diseases: insights from population geneticsMerging molecular mechanism and evolution: theory and computation at the interface of biophysics and evolutionary population geneticsGenome-scale analysis of demographic history and adaptive selectionPopulation genetic tools for dissecting innate immunity in humansFrom trans to cis: transcriptional regulatory networks in neocortical developmentReduced food intake and body weight in mice deficient for the G protein-coupled receptor GPR82Reference-free population genomics from next-generation transcriptome data and the vertebrate-invertebrate gapUnderstanding rare and common diseases in the context of human evolutionEvolutionary dynamics of human Toll-like receptors and their different contributions to host defenseRecent and ongoing selection in the human genomeToward a selection theory of molecular evolutionDetecting positive and purifying selection at synonymous sites in yeast and worm
P2860
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P2860
Natural selection on protein-coding genes in the human genome
description
2005 nî lūn-bûn
@nan
2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Natural selection on protein-coding genes in the human genome
@ast
Natural selection on protein-coding genes in the human genome
@en
type
label
Natural selection on protein-coding genes in the human genome
@ast
Natural selection on protein-coding genes in the human genome
@en
prefLabel
Natural selection on protein-coding genes in the human genome
@ast
Natural selection on protein-coding genes in the human genome
@en
P2093
P2860
P3181
P356
P1433
P1476
Natural selection on protein-coding genes in the human genome
@en
P2093
Adi Fledel-Alon
Andrew G Clark
Daniel Civello
David M Tanenbaum
John J Sninsky
Mark D Adams
Melissa Todd Hubisz
Michele Cargill
Ryan D Hernandez
Scott Williamson
P2860
P2888
P304
P3181
P356
10.1038/NATURE04240
P407
P577
2005-10-01T00:00:00Z
P5875
P6179
1041792930