Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor
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Androgen deprivation-induced senescence promotes outgrowth of androgen-refractory prostate cancer cellsThe secreted protein S100A7 (psoriasin) is induced by telomere dysfunction in human keratinocytes independently of a DNA damage response and cell cycle regulatorsFeedback between p21 and reactive oxygen production is necessary for cell senescenceAutophagy mediates the mitotic senescence transitionCellular senescence controls fibrosis in wound healingAndrogen depletion induces senescence in prostate cancer cells through down-regulation of Skp2DNA damage-mediated induction of a chemoresistant nicheAdipose tissue endothelial cells from obese human subjects: differences among depots in angiogenic, metabolic, and inflammatory gene expression and cellular senescenceThe matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healingExpression of p16(INK4a) in peripheral blood T-cells is a biomarker of human agingMicroRNAs miR-146a/b negatively modulate the senescence-associated inflammatory mediators IL-6 and IL-8DNA Damage Response and Immune Defense: Links and MechanismsSenescence in Human Mesenchymal Stem Cells: Functional Changes and Implications in Stem Cell-Based TherapyDNA Damage Response in Hematopoietic Stem Cell AgeingRole of the microbiome in non-gastrointestinal cancersConnecting the Dots: From DNA Damage and Repair to AgingMolecular mechanisms of biological aging in intervertebral discsCellular Senescence as the Causal Nexus of AgingWhen stem cells grow old: phenotypes and mechanisms of stem cell agingCellular senescence in aging and age-related disease: from mechanisms to therapyChanges in Regenerative Capacity through LifespanThe Role of the Transcriptional Regulation of Stromal Cells in Chronic InflammationCellular Senescence and the Biology of Aging, Disease, and FrailtyNon-autonomous overgrowth by oncogenic niche cells: Cellular cooperation and competition in tumorigenesisReplication Stress: A Lifetime of Epigenetic ChangeNoncoding RNA control of cellular senescenceThe central role of muscle stem cells in regenerative failure with agingThe impact of cellular senescence in cancer therapy: is it true or not?SIRT1 as a therapeutic target in inflammaging of the pulmonary diseaseMolecular turnover, the H3.3 dilemma and organismal aging (hypothesis)Macroautophagy and the oncogene-induced senescenceRadiation-Induced Bystander Response: Mechanism and Clinical ImplicationsRoles and mechanisms of cellular senescence in regulation of tissue homeostasisIGF-Binding Protein 2 - Oncogene or Tumor Suppressor?NF-κB in cellular senescence and cancer treatmentOf flies, mice, and men: evolutionarily conserved tissue damage responses and agingDisruptive chemicals, senescence and immortalityTherapeutic targeting of replicative immortalityDynamic modelling of pathways to cellular senescence reveals strategies for targeted interventionsReorganization of chromosome architecture in replicative cellular senescence
P2860
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P2860
Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor
description
2008 nî lūn-bûn
@nan
2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Senescence-associated secretor ...... S and the p53 tumor suppressor
@ast
Senescence-associated secretor ...... S and the p53 tumor suppressor
@en
type
label
Senescence-associated secretor ...... S and the p53 tumor suppressor
@ast
Senescence-associated secretor ...... S and the p53 tumor suppressor
@en
prefLabel
Senescence-associated secretor ...... S and the p53 tumor suppressor
@ast
Senescence-associated secretor ...... S and the p53 tumor suppressor
@en
P2093
P2860
P3181
P1433
P1476
Senescence-associated secretor ...... S and the p53 tumor suppressor
@en
P2093
Christopher K Patil
Denise P Muñoz
Jean-Philippe Coppé
Joshua Goldstein
Judith Campisi
Peter S Nelson
Pierre-Yves Desprez
P2860
P304
P3181
P356
10.1371/JOURNAL.PBIO.0060301
P407
P577
2008-12-01T00:00:00Z