Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor - sprookjes - yvandenbroek - TriplyDB

Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor

Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor

http://www.wikidata.org/entity/Q29615559

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Androgen deprivation-induced senescence promotes outgrowth of androgen-refractory prostate cancer cells The secreted protein S100A7 (psoriasin) is induced by telomere dysfunction in human keratinocytes independently of a DNA damage response and cell cycle regulators Feedback between p21 and reactive oxygen production is necessary for cell senescence Autophagy mediates the mitotic senescence transition Cellular senescence controls fibrosis in wound healing Androgen depletion induces senescence in prostate cancer cells through down-regulation of Skp2 DNA damage-mediated induction of a chemoresistant niche Adipose tissue endothelial cells from obese human subjects: differences among depots in angiogenic, metabolic, and inflammatory gene expression and cellular senescence The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing Expression of p16(INK4a) in peripheral blood T-cells is a biomarker of human aging MicroRNAs miR-146a/b negatively modulate the senescence-associated inflammatory mediators IL-6 and IL-8 DNA Damage Response and Immune Defense: Links and Mechanisms Senescence in Human Mesenchymal Stem Cells: Functional Changes and Implications in Stem Cell-Based Therapy DNA Damage Response in Hematopoietic Stem Cell Ageing Role of the microbiome in non-gastrointestinal cancers Connecting the Dots: From DNA Damage and Repair to Aging Molecular mechanisms of biological aging in intervertebral discs Cellular Senescence as the Causal Nexus of Aging When stem cells grow old: phenotypes and mechanisms of stem cell aging Cellular senescence in aging and age-related disease: from mechanisms to therapy Changes in Regenerative Capacity through Lifespan The Role of the Transcriptional Regulation of Stromal Cells in Chronic Inflammation Cellular Senescence and the Biology of Aging, Disease, and Frailty Non-autonomous overgrowth by oncogenic niche cells: Cellular cooperation and competition in tumorigenesis Replication Stress: A Lifetime of Epigenetic Change Noncoding RNA control of cellular senescence The central role of muscle stem cells in regenerative failure with aging The impact of cellular senescence in cancer therapy: is it true or not?SIRT1 as a therapeutic target in inflammaging of the pulmonary disease Molecular turnover, the H3.3 dilemma and organismal aging (hypothesis)Macroautophagy and the oncogene-induced senescence Radiation-Induced Bystander Response: Mechanism and Clinical Implications Roles and mechanisms of cellular senescence in regulation of tissue homeostasis IGF-Binding Protein 2 - Oncogene or Tumor Suppressor?NF-κB in cellular senescence and cancer treatment Of flies, mice, and men: evolutionarily conserved tissue damage responses and aging Disruptive chemicals, senescence and immortality Therapeutic targeting of replicative immortality Dynamic modelling of pathways to cellular senescence reveals strategies for targeted interventions Reorganization of chromosome architecture in replicative cellular senescence

P2860

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P2860

Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor

http://www.wikidata.org/entity/Q29615559

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2008 nî lūn-bûn

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2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Senescence-associated secretor ...... S and the p53 tumor suppressor

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Senescence-associated secretor ...... S and the p53 tumor suppressor

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type

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Senescence-associated secretor ...... S and the p53 tumor suppressor

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Senescence-associated secretor ...... S and the p53 tumor suppressor

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Senescence-associated secretor ...... S and the p53 tumor suppressor

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Senescence-associated secretor ...... S and the p53 tumor suppressor

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Senescence-associated secretor ...... S and the p53 tumor suppressor

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Christopher K Patil

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Denise P Muñoz

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Jean-Philippe Coppé

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Joshua Goldstein

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Judith Campisi

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Peter S Nelson

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Pierre-Yves Desprez

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Yu Sun

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P2860

Oncogene-Induced Senescence: Putting the Brakes on Tumor Development

The Hallmarks of Cancer

Higher-order nuclear organization in growth arrest of human mammary epithelial cells: a novel role for telomere-associated protein TIN2

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

Inflammation and cancer

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network.

Putting tumours in context

Tumor suppression by Ink4a-Arf: progress and puzzles

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10.1371/JOURNAL.PBIO.0060301

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19053174

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