Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes - sprookjes - yvandenbroek - TriplyDB

Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes

Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes

http://www.wikidata.org/entity/Q29616326

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Pathophysiological power of improper tonic GABA(A) conductances in mature and immature models.Circuit specific functions of cannabinoid CB1 receptor in the balance of investigatory drive and exploration Neuropathology and animal models of autism: genetic and environmental factors Alterations of GABAergic signaling in autism spectrum disorders Mitochondrial dysfunction in Pten haplo-insufficient mice with social deficits and repetitive behavior: interplay between Pten and p53 Acupuncture for autism spectrum disorders (ASD)Functional Properties of Human Stem Cell-Derived Neurons in Health and Disease Clinical and Neurobiological Relevance of Current Animal Models of Autism Spectrum Disorders.Recent advances in understanding synaptic abnormalities in Rett syndrome Developmental Dynamics of Rett Syndrome Genetics of Autism Spectrum Disorder: Current Status and Possible Clinical Applications Genes, circuits, and precision therapies for autism and related neurodevelopmental disorders Excitatory/Inhibitory Balance and Circuit Homeostasis in Autism Spectrum Disorders Optogenetics: 10 years of microbial opsins in neuroscience.MECP2 disorders: from the clinic to mice and back Investigation of Rett syndrome using pluripotent stem cells Astrocytes conspire with neurons during progression of neurological disease The impact of MeCP2 loss- or gain-of-function on synaptic plasticity Channelopathy pathogenesis in autism spectrum disorders The molecular basis of cognitive deficits in pervasive developmental disorders GABAergic signaling as therapeutic target for autism spectrum disorders Inhibition-Based Biomarkers for Autism Spectrum Disorder.NINDS epilepsy and autism spectrum disorders workshop report Targeted pharmacological treatment of autism spectrum disorders: fragile X and Rett syndromes Environment, dysbiosis, immunity and sex-specific susceptibility: a translational hypothesis for regressive autism pathogenesis Circuit dynamics of adaptive and maladaptive behaviour GABA and glutamate pathways are spatially and developmentally affected in the brain of Mecp2-deficient mice Reversal of phenotypes in MECP2 duplication mice using genetic rescue or antisense oligonucleotides.Premature changes in neuronal excitability account for hippocampal network impairment and autistic-like behavior in neonatal BTBR T+tf/J mice.The parvalbumin/somatostatin ratio is increased in Pten mutant mice and by human PTEN ASD alleles.A computational perspective on autism.Rescue of inhibitory synapse strength following developmental hearing loss PX-RICS-deficient mice mimic autism spectrum disorder in Jacobsen syndrome through impaired GABAA receptor trafficking A Spontaneous Missense Mutation in Branched Chain Keto Acid Dehydrogenase Kinase in the Rat Affects Both the Central and Peripheral Nervous Systems Mutation of the CH1 Domain in the Histone Acetyltransferase CREBBP Results in Autism-Relevant Behaviors in Mice Serotonin neurons in the dorsal raphe nucleus encode reward signals Rett Syndrome: Reaching for Clinical Trials Duration of culture and sonic hedgehog signaling differentially specify PV versus SST cortical interneuron fates from embryonic stem cells Genetic aspects of autism spectrum disorders: insights from animal models Rett syndrome - biological pathways leading from MECP2 to disorder phenotypes

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Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes

http://www.wikidata.org/entity/Q29616326

description

2010 nî lūn-bûn

@nan

2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

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2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

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2010年论文

@wuu

name

Dysfunction in GABA signalling ...... s and Rett syndrome phenotypes

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Dysfunction in GABA signalling ...... s and Rett syndrome phenotypes

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type

label

Dysfunction in GABA signalling ...... s and Rett syndrome phenotypes

@ast

Dysfunction in GABA signalling ...... s and Rett syndrome phenotypes

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prefLabel

Dysfunction in GABA signalling ...... s and Rett syndrome phenotypes

@ast

Dysfunction in GABA signalling ...... s and Rett syndrome phenotypes

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Dysfunction in GABA signalling ...... s and Rett syndrome phenotypes

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Hongmei Chen

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Hsiao-Tuan Chao

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Hui-Chen Lu

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John L R Rubenstein

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Jong Yoo

http://www.w3.org/2001/XMLSchema#string

Marc Ekker

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Nathaniel Heintz

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Shiaoching Gong

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Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

Reduced cortical activity due to a shift in the balance between excitation and inhibition in a mouse model of Rett syndrome

A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice

Loss of MeCP2 in aminergic neurons causes cell-autonomous defects in neurotransmitter synthesis and specific behavioral abnormalities

Integrated epigenomic analyses of neuronal MeCP2 reveal a role for long-range interaction with active genes

Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus

Identification of MeCP2 mutations in a series of females with autistic disorder

Neural circuit regulation of prepulse inhibition of startle in the rat: current knowledge and future challenges

The story of Rett syndrome: from clinic to neurobiology

Subregion- and cell type-restricted gene knockout in mouse brain

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263-269

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scholarly article

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636157

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10.1038/NATURE09582

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7321

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468

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Christian Rosenmund

Jeffrey L. Noebels

Jeffrey L. Neul

Maria H Chahrour

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2010-11-01T00:00:00Z

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47743040

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1047116896

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21068835

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gamma-aminobutyric acid signaling pathway

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3057962

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