Structural design and molecular evolution of a cytokine receptor superfamily
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Crystal structure of LIR-2 (ILT4) at 1.8 A: differences from LIR-1 (ILT2) in regions implicated in the binding of the Human Cytomegalovirus class I MHC homolog UL18.Characterization of a human MHC class III region gene product with S-thioesterase activityCharged residues dominate a unique interlocking topography in the heterodimeric cytokine interleukin-12The ciliary neurotrophic factor receptor alpha component induces the secretion of and is required for functional responses to cardiotrophin-like cytokineA soluble class II cytokine receptor, IL-22RA2, is a naturally occurring IL-22 antagonistEstrogen inhibits GH signaling by suppressing GH-induced JAK2 phosphorylation, an effect mediated by SOCS-2Molecular cloning and expression of the human interleukin 5 receptorMolecular basis of the membrane-anchored and two soluble isoforms of the human interleukin 5 receptor alpha subunitA single amino acid substitution in the exoplasmic domain of the human growth hormone (GH) receptor confers familial GH resistance (Laron syndrome) with positive GH-binding activity by abolishing receptor homodimerizationThe orphan receptor CRF2-4 is an essential subunit of the interleukin 10 receptorMolecular and structural basis of cytokine receptor pleiotropy in the interleukin-4/13 systemaxl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinaseMutant U5A cells are complemented by an interferon-alpha beta receptor subunit generated by alternative processing of a new member of a cytokine receptor gene clusterA novel interleukin-12 p40-related protein induced by latent Epstein-Barr virus infection in B lymphocytesEpstein-Barr virus-induced gene 3 and the p35 subunit of interleukin 12 form a novel heterodimeric hematopoietinThe structure of interleukin-23 reveals the molecular basis of p40 subunit sharing with interleukin-12Definition and spatial location of mouse interleukin-2 residues that interact with its heterotrimeric receptorA novel endothelial cell surface receptor tyrosine kinase with extracellular epidermal growth factor homology domainsCloning of a murine IL-11 receptor alpha-chain; requirement for gp130 for high affinity binding and signal transductionThe lymphocyte glycoprotein CD6 contains a repeated domain structure characteristic of a new family of cell surface and secreted proteinsOncostatin M is a member of a cytokine family that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6A model of the ternary complex of interleukin-10 with its soluble receptors.Small glutamine-rich tetratricopeptide repeat-containing protein (SGT) interacts with the ubiquitin-dependent endocytosis (UbE) motif of the growth hormone receptorInterleukin-6-type cytokine signalling through the gp130/Jak/STAT pathwayThe leptin receptor promoter controls expression of a second distinct proteinCritical cytoplasmic region of the interleukin 6 signal transducer gp130 is conserved in the cytokine receptor familyEvidence of free and bound leptin in human circulation. Studies in lean and obese subjects and during short-term fastingIdentification and molecular cloning of a soluble human granulocyte-macrophage colony-stimulating factor receptorThe structure of granulocyte-colony-stimulating factor and its relationship to other growth factorsProposed acquisition of an animal protein domain by bacteriaA receptor for interleukin 10 is related to interferon receptorsActivation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130Structure-function analysis of human IL-6 receptor: dissociation of amino acid residues required for IL-6-binding and for IL-6 signal transduction through gp130The integrity of the conserved 'WS motif' common to IL-2 and other cytokine receptors is essential for ligand binding and signal transductionFunctional domains of the granulocyte colony-stimulating factor receptorA novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoietin receptorsTec kinase associates with c-kit and is tyrosine phosphorylated and activated following stem cell factor bindingMultiple regions within the cytoplasmic domains of the leukemia inhibitory factor receptor and gp130 cooperate in signal transduction in hepatic and neuronal cellsComparative genomic analysis of the interferon/interleukin-10 receptor gene clusterHuman interleukin-3 (IL-3) induces disulfide-linked IL-3 receptor alpha- and beta-chain heterodimerization, which is required for receptor activation but not high-affinity binding
P2860
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P2860
Structural design and molecular evolution of a cytokine receptor superfamily
description
1990 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 1990
@ast
im September 1990 veröffentlichter wissenschaftlicher Artikel
@de
scientific article (publication date: September 1990)
@en
wetenschappelijk artikel (gepubliceerd in 1990-09)
@nl
наукова стаття, опублікована у вересні 1990
@uk
مقالة علمية (نشرت في سبتمبر 1990)
@ar
name
Structural design and molecular evolution of a cytokine receptor superfamily
@ast
Structural design and molecular evolution of a cytokine receptor superfamily
@en
type
label
Structural design and molecular evolution of a cytokine receptor superfamily
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Structural design and molecular evolution of a cytokine receptor superfamily
@en
prefLabel
Structural design and molecular evolution of a cytokine receptor superfamily
@ast
Structural design and molecular evolution of a cytokine receptor superfamily
@en
P2860
P1476
Structural design and molecular evolution of a cytokine receptor superfamily
@en
P2093
P2860
P304
P407
P577
1990-09-01T00:00:00Z