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A large scale shRNA barcode screen identifies the circadian clock component ARNTL as putative regulator of the p53 tumor suppressor pathwayA toxicology suite adapted for comparing parallel toxicity responses of model human lung cells to diesel exhaust particles and their extractsThe balance between rRNA and ribosomal protein synthesis up- and downregulates the tumour suppressor p53 in mammalian cellsRegulation of p53 stability and function by the deubiquitinating enzyme USP42RBB, a novel transcription repressor, represses the transcription of HDM2 oncogeneRFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damageRegulation of p53 tetramerization and nuclear export by ARCAcetylation is indispensable for p53 activationTSPYL5 suppresses p53 levels and function by physical interaction with USP7VRK1 interacts with p53 forming a basal complex that is activated by UV-induced DNA damagePolo-like kinase-1 phosphorylates MDM2 at Ser260 and stimulates MDM2-mediated p53 turnoverMutational analysis reveals a dual role of Mdm2 acidic domain in the regulation of p53 stabilityRotavirus-encoded nonstructural protein 1 modulates cellular apoptotic machinery by targeting tumor suppressor protein p53Differential regulation of p53 and p21 by MKRN1 E3 ligase controls cell cycle arrest and apoptosisTrim24 targets endogenous p53 for degradationThe DNA-damage response in human biology and diseaseCellular senescence and tumor suppressor gene p16Effects of MDM2 promoter polymorphisms and p53 codon 72 polymorphism on risk and age at onset of squamous cell carcinoma of the head and neckModel of human aging: recent findings on Werner's and Hutchinson-Gilford progeria syndromesModulation of intracellular ROS levels by TIGAR controls autophagyLysine acetylation: codified crosstalk with other posttranslational modificationsTwo-round coamplification at lower denaturation temperature-PCR (COLD-PCR)-based sanger sequencing identifies a novel spectrum of low-level mutations in lung adenocarcinomaMapping the interactions of the p53 transactivation domain with the KIX domain of CBPNutlin-3a activates p53 to both down-regulate inhibitor of growth 2 and up-regulate mir-34a, mir-34b, and mir-34c expression, and induce senescenceRegulation of autophagy by cytoplasmic p53A panel of isogenic human cancer cells suggests a therapeutic approach for cancers with inactivated p53Genomic Changes in Normal Breast Tissue in Women at Normal Risk or at High Risk for Breast CancerChemical Variations on the p53 Reactivation ThemeApoptosis as anticancer mechanism: function and dysfunction of its modulators and targeted therapeutic strategiesChalcone Scaffold in Anticancer Armamentarium: A Molecular InsightThe Role of Gammaherpesviruses in Cancer PathogenesisAlterations in Mitochondrial and Endoplasmic Reticulum Signaling by p53 MutantsTranscriptome and Molecular Endocrinology Aspects of Epicardial Adipose Tissue in Cardiovascular Diseases: A Systematic Review and Meta-Analysis of Observational StudiesDiametrical diseases reflect evolutionary-genetic tradeoffs: Evidence from psychiatry, neurology, rheumatology, oncology and immunologyRole of ZAC1 in transient neonatal diabetes mellitus and glucose metabolismNucleolar activity in neurodegenerative diseases: a missing piece of the puzzle?Running forward: new frontiers in endurance exercise biologySelf-consumption: the interplay of autophagy and apoptosisImprinted Zac1 in neural stem cellsSystems biology of cisplatin resistance: past, present and future
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
p53 in health and disease
@ast
p53 in health and disease
@en
type
label
p53 in health and disease
@ast
p53 in health and disease
@en
prefLabel
p53 in health and disease
@ast
p53 in health and disease
@en
P3181
P356
P1476
p53 in health and disease
@en
P2093
Karen H Vousden
P2888
P304
P3181
P356
10.1038/NRM2147
P407
P50
P577
2007-04-01T00:00:00Z
P5875
P6179
1002243416