SH3BP2 cherubism mutation potentiates TNF-α-induced osteoclastogenesis via NFATc1 and TNF-α-mediated inflammatory bone loss.

SH3BP2 cherubism mutation potentiates TNF-α-induced osteoclastogenesis via NFATc1 and TNF-α-mediated inflammatory bone loss.

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http://www.wikidata.org/entity/Q30009398
Loss of SH3 domain-binding protein 2 function suppresses bone destruction in tumor necrosis factor-driven and collagen-induced arthritis in miceBone marrow transplantation improves autoinflammation and inflammatory bone loss in SH3BP2 knock-in cherubism miceSH3BP2 gain-of-function mutation exacerbates inflammation and bone loss in a murine collagen-induced arthritis modelImmunological loss-of-function due to genetic gain-of-function in humans: autosomal dominance of the third kindClinical and genetic analysis of patients with cherubism.Concise Review: Stem Cells in Osteoimmunology.Syk-dependent tyrosine phosphorylation of 3BP2 is required for optimal FcRγ-mediated phagocytosis and chemokine expression in U937 cells.Inflammation in bone physiology and pathology.Cherubism Mice Also Deficient in c-Fos Exhibit Inflammatory Bone Destruction Executed by Macrophages That Express MMP14 Despite the Absence of TRAP+ Osteoclasts.TNF‑α and RANKL promote osteoclastogenesis by upregulating RANK via the NF‑κB pathway.The classification, genetic diagnosis and modelling of monogenic autoinflammatory disordersMolecular and cellular characterizations of human cherubism: disease aggressiveness depends on osteoclast differentiation
P2860

SH3BP2 cherubism mutation potentiates TNF-α-induced osteoclastogenesis via NFATc1 and TNF-α-mediated inflammatory bone loss.

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http://www.wikidata.org/entity/Q30009398
description
2014 nî lūn-bûn
@nan
2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
SH3BP2 cherubism mutation pote ...... diated inflammatory bone loss.
@ast
SH3BP2 cherubism mutation pote ...... diated inflammatory bone loss.
@en
type
label
SH3BP2 cherubism mutation pote ...... diated inflammatory bone loss.
@ast
SH3BP2 cherubism mutation pote ...... diated inflammatory bone loss.
@en
prefLabel
SH3BP2 cherubism mutation pote ...... diated inflammatory bone loss.
@ast
SH3BP2 cherubism mutation pote ...... diated inflammatory bone loss.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P921
P932
P356
P1433
P1476
SH3BP2 cherubism mutation pote ...... diated inflammatory bone loss.
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P921
P932