Construction of new ligand binding sites in proteins of known structure
about
The crystal structure of human protein farnesyltransferase reveals the basis for inhibition by CaaX tetrapeptides and their mimeticsWhat determines the strength of noncovalent association of ligands to proteins in aqueous solution?Protein design: toward functional metalloenzymesRetrostructural analysis of metalloproteins: application to the design of a minimal model for diiron proteinsIntroduction and characterization of a functionally linked metal ion binding site at the exposed heme edge of myoglobinEngineering a zinc binding site into the de novo designed protein DS119 with a βαβ structureOn the origin and highly likely completeness of single-domain protein structures.Designing hydrolytic zinc metalloenzymesComputational approaches for rational design of proteins with novel functionalitiesOptGraft: A computational procedure for transferring a binding site onto an existing protein scaffold.Integration of Diverse Research Methods to Analyze and Engineer Ca-Binding Proteins: From Prediction to ProductionComputational protein engineering: bridging the gap between rational design and laboratory evolution.Achievements and Challenges in Computational Protein Design.Designing artificial enzymes by intuition and computationOptimal sequence selection in proteins of known structure by simulated evolution.Lanthanide-binding helix-turn-helix peptides: solution structure of a designed metallonuclease.Histidine placement in de novo-designed heme proteins.Conformational diversity and computational enzyme designCombinatorial methods for small-molecule placement in computational enzyme design.The minimized dead-end elimination criterion and its application to protein redesign in a hybrid scoring and search algorithm for computing partition functions over molecular ensembles.TransCent: computational enzyme design by transferring active sites and considering constraints relevant for catalysis.Identification and dissection of Ca(2+)-binding sites in the extracellular domain of Ca(2+)-sensing receptor.A matching algorithm for catalytic residue site selection in computational enzyme design.Enzyme-like proteins by computational designAutoMatch: target-binding protein design and enzyme design by automatic pinpointing potential active sites in available protein scaffolds.RASMOT-3D PRO: a 3D motif search webserver.Transferable coarse-grained potential for de novo protein folding and designNonnatural protein-protein interaction-pair design by key residues grafting.Rational design of nascent metalloenzymesConversion of a maltose receptor into a zinc biosensor by computational design.Use of an Improved Matching Algorithm to Select Scaffolds for Enzyme Design Based on a Complex Active Site ModelRational protein design: combining theory and experiment.The rational design of allosteric interactions in a monomeric protein and its applications to the construction of biosensorsConstruction of a catalytically active iron superoxide dismutase by rational protein design.Computational design of a Zn2+ receptor that controls bacterial gene expression.The rational design and construction of a cuboidal iron-sulfur protein.The de novo design of a rubredoxin-like Fe site.A critical analysis of computational protein design with sparse residue interaction graphs.Protein fabrication automationConstruction of a fluorescent biosensor family.
P2860
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P2860
Construction of new ligand binding sites in proteins of known structure
description
1991 nî lūn-bûn
@nan
1991 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
Construction of new ligand binding sites in proteins of known structure
@ast
Construction of new ligand binding sites in proteins of known structure
@en
type
label
Construction of new ligand binding sites in proteins of known structure
@ast
Construction of new ligand binding sites in proteins of known structure
@en
prefLabel
Construction of new ligand binding sites in proteins of known structure
@ast
Construction of new ligand binding sites in proteins of known structure
@en
P3181
P1476
Construction of new ligand binding sites in proteins of known structure
@en
P2093
Frederic M. Richards
Homme W. Hellinga
P304
P3181
P356
10.1016/0022-2836(91)90510-D
P407
P577
1991-12-01T00:00:00Z