about
Trypanosoma brucei modifies the tsetse salivary composition, altering the fly feeding behavior that favors parasite transmissionExpression and extracellular release of a functional anti-trypanosome Nanobody® in Sodalis glossinidius, a bacterial symbiont of the tsetse flyApolipoprotein L-I is the trypanosome lytic factor of human serumTumor-associated macrophages in breast cancer: distinct subsets, distinct functionsAmastigote Load and Cell Surface Phenotype of Infected Cells from Lesions and Lymph Nodes of Susceptible and Resistant Mice Infected with Leishmania majorAlternatively activated myeloid cells limit pathogenicity associated with African trypanosomiasis through the IL-10 inducible gene selenoprotein P.Macrophage reprogramming by mycolic acid promotes a tolerogenic response in experimental asthmaIdentification of a tsetse fly salivary protein with dual inhibitory action on human platelet aggregationAffinity is an important determinant of the anti-trypanosome activity of nanobodiesMonocytes contribute to differential immune pressure on R5 versus X4 HIV through the adipocytokine visfatin/NAMPTNanobodies as novel agents for cancer therapy.Differential expression of FIZZ1 and Ym1 in alternatively versus classically activated macrophages.Parallel selection of multiple anti-infectome Nanobodies without access to purified antigens.Efficient targeting of conserved cryptic epitopes of infectious agents by single domain antibodies. African trypanosomes as paradigm.Efficient cancer therapy with a nanobody-based conjugate.The role of B-cells and IgM antibodies in parasitemia, anemia, and VSG switching in Trypanosoma brucei-infected miceMIF-Mediated Hemodilution Promotes Pathogenic Anemia in Experimental African TrypanosomosisIdentification of a functional Antigen5-related allergen in the saliva of a blood feeding insect, the tsetse fly.A novel promiscuous class of camelid single-domain antibody contributes to the antigen-binding repertoire.Tip-DC development during parasitic infection is regulated by IL-10 and requires CCL2/CCR2, IFN-gamma and MyD88 signaling.High affinity nanobodies against the Trypanosome brucei VSG are potent trypanolytic agents that block endocytosisDo-it-yourself: construction of a custom cDNA macroarray platform with high sensitivity and linear range.Infection stage-dependent modulation of macrophage activation in Trypanosoma congolense-resistant and -susceptible mice.MIF contributes to Trypanosoma brucei associated immunopathogenicity developmentTsetse salivary gland proteins 1 and 2 are high affinity nucleic acid binding proteins with residual nuclease activity.Classical and alternative activation of mononuclear phagocytes: picking the best of both worlds for tumor promotion.Secretory leukocyte protease inhibitor promotes the tumorigenic and metastatic potential of cancer cellsA Trypanosoma brucei kinesin heavy chain promotes parasite growth by triggering host arginase activity.Development of a pHrodo-based assay for the assessment of in vitro and in vivo erythrophagocytosis during experimental trypanosomosisTsetse fly saliva accelerates the onset of Trypanosoma brucei infection in a mouse model associated with a reduced host inflammatory response.Visceral leishmaniasis relapse in HIV patients--a role for myeloid-derived suppressor cells?Ly6C- Monocytes Regulate Parasite-Induced Liver Inflammation by Inducing the Differentiation of Pathogenic Ly6C+ Monocytes into MacrophagesAlternatively activated macrophages during parasite infections.E-cadherin expression in macrophages dampens their inflammatory responsiveness in vitro, but does not modulate M2-regulated pathologies in vivoMacrophages, PPARs, and Cancer.African trypanosomosis: from immune escape and immunopathology to immune intervention.Alternatively activated macrophages in protozoan infections.
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Patrick De Baetselier
@ast
Patrick De Baetselier
@en
Patrick De Baetselier
@es
Patrick De Baetselier
@nl
Patrick De Baetselier
@sl
type
label
Patrick De Baetselier
@ast
Patrick De Baetselier
@en
Patrick De Baetselier
@es
Patrick De Baetselier
@nl
Patrick De Baetselier
@sl
prefLabel
Patrick De Baetselier
@ast
Patrick De Baetselier
@en
Patrick De Baetselier
@es
Patrick De Baetselier
@nl
Patrick De Baetselier
@sl