about
sameAs
P688
A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidaseA novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9ACE2: from vasopeptidase to SARS virus receptorEvaluation of angiotensin-converting enzyme (ACE), its homologue ACE2 and neprilysin in angiotensin peptide metabolismCloning and characterization of a secreted form of angiotensin-converting enzyme 2A transmembrane serine protease is linked to the severe acute respiratory syndrome coronavirus receptor and activates virus entryIdentification of residues in the receptor-binding domain (RBD) of the spike protein of human coronavirus NL63 that are critical for the RBD-ACE2 receptor interactionAngiotensin-converting enzyme 2 overexpression in the subfornical organ prevents the angiotensin II-mediated pressor and drinking responses and is associated with angiotensin II type 1 receptor downregulationLipid rafts are involved in SARS-CoV entry into Vero E6 cellsHeart block, ventricular tachycardia, and sudden death in ACE2 transgenic mice with downregulated connexinsACE2: a new target for cardiovascular disease therapeuticsTMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike proteinHydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidaseModulation of TNF-alpha-converting enzyme by the spike protein of SARS-CoV and ACE2 induces TNF-alpha production and facilitates viral entryTissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis.HeLa-ACE2-TMPRSS2 Cells Are Useful for the Isolation of Human Coronavirus 229E.Tissue-specific amino acid transporter partners ACE2 and collectrin differentially interact with hartnup mutations.Structural basis for the recognition of the SARS-CoV-2 by full-length human ACE2The proximal origin of SARS-CoV-2Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic targetSARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease InhibitorACE2 Expression is Increased in the Lungs of Patients with Comorbidities Associated with Severe COVID-19Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronavirusesAngiotensin receptor blockers as tentative SARS-CoV-2 therapeuticsCell entry mechanisms of SARS-CoV-2Broad and differential animal ACE2 receptor usage by SARS-CoV-2TMPRSS2 and ACE2 Coexpression in SARS-CoV-2 Salivary Glands InfectionSingle-cell RNA analysis on ACE2 expression provides insights into SARS-CoV-2 potential entry into the bloodstream and heart injury
P921
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in Angiotensin I converting enzyme 2
@nl
protèin
@ace
protéine
@fr
بروتين في الإنسان العاقل
@ar
name
Angiotensin I converting enzyme 2
@en
Angiotensin-konvertujući enzim 2
@sh
Enzima conversora da angiotensina 2
@pt
Enzyme de conversion de l'angiotensine 2
@fr
angiotenzin-konvertujući enzim 2
@sr-el
ангиотензин-конвертујући ензим 2
@sr
ангиотензин-конвертујући ензим 2
@sr-ec
血管紧张素转化酶2
@zh
type
label
Angiotensin I converting enzyme 2
@en
Angiotensin-konvertujući enzim 2
@sh
Enzima conversora da angiotensina 2
@pt
Enzyme de conversion de l'angiotensine 2
@fr
angiotenzin-konvertujući enzim 2
@sr-el
ангиотензин-конвертујући ензим 2
@sr
ангиотензин-конвертујући ензим 2
@sr-ec
血管紧张素转化酶2
@zh
altLabel
ACE-related carboxypeptidase
@en
ACE2
@en
ACEH
@en
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
@en
angiotensin-converting enzyme 2
@en
angiotensin-converting enzyme homolog
@en
metalloprotease MPROT15
@en
peptidyl-dipeptidase A
@en
prefLabel
Angiotensin I converting enzyme 2
@en
Angiotensin-konvertujući enzim 2
@sh
Enzima conversora da angiotensina 2
@pt
Enzyme de conversion de l'angiotensine 2
@fr
angiotenzin-konvertujući enzim 2
@sr-el
ангиотензин-конвертујући ензим 2
@sr
ангиотензин-конвертујући ензим 2
@sr-ec
血管紧张素转化酶2
@zh
P638
P680
P681
P682
P352
P486
P646
P2888
P31
P352
P486
P637
NP_001358344
P638
P646
P672
D08.811.277.656.350.350.687
