Increased production of 12/15 lipoxygenase eicosanoids accelerates monocyte/endothelial interactions in diabetic db/db mice.
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Reduced expression of ATP-binding cassette transporter G1 increases cholesterol accumulation in macrophages of patients with type 2 diabetes mellitusG2A deficiency in mice promotes macrophage activation and atherosclerosis.Lipids and the endothelium: bidirectional interactionsReactive Oxygen Species (ROS) Mediate p300-dependent STAT1 Protein Interaction with Peroxisome Proliferator-activated Receptor (PPAR)-γ in CD36 Protein Expression and Foam Cell FormationEffects of silencing leukocyte-type 12/15-lipoxygenase using short interfering RNAsImpaired arachidonic acid-mediated dilation of small mesenteric arteries in Zucker diabetic fatty ratsEliminating or blocking 12/15-lipoxygenase reduces neutrophil recruitment in mouse models of acute lung injuryMurine 12/15-lipoxygenase regulates ATP-binding cassette transporter G1 protein degradation through p38- and JNK2-dependent pathways.Improved survival and reduced vascular permeability by eliminating or blocking 12/15-lipoxygenase in mouse models of acute lung injury (ALI).Human lipoxygenase pathway gene variation and association with markers of subclinical atherosclerosis in the diabetes heart study.Sphingosine-1-phosphate inhibits high glucose-mediated ERK1/2 action in endothelium through induction of MAP kinase phosphatase-3.12/15-Lipoxygenase activity increases the degradation of macrophage ATP-binding cassette transporter G1.12/15-lipoxygenase is required for the early onset of high fat diet-induced adipose tissue inflammation and insulin resistance in miceMyD88-dependent interplay between myeloid and endothelial cells in the initiation and progression of obesity-associated inflammatory diseases.Modified citrus pectin inhibits galectin-3 function to reduce atherosclerotic lesions in apoE-deficient mice.Modulating Notch signaling to enhance neovascularization and reperfusion in diabetic mice.Specific monocyte adhesion to endothelial cells induced by oxidized phospholipids involves activation of cPLA2 and lipoxygenase.ROS-dependent Syk and Pyk2-mediated STAT1 activation is required for 15(S)-hydroxyeicosatetraenoic acid-induced CD36 expression and foam cell formationDiet-induced adipose tissue inflammation and liver steatosis are prevented by DPP-4 inhibition in diabetic mice.Epigenetic mechanisms in diabetic vascular complications.12/15-Lipoxygenase-dependent ROS production is required for diet-induced endothelial barrier dysfunction.Eicosanoids, β-cell function, and diabetesEffect of gestational hypercholesterolemia and maternal immunization on offspring plasma eicosanoidsInhibition of renin release by arachidonic acid metabolites, 12(s)-HPETE and 12-HETE: role of TRPV1 channelsEicosanoids and renal damage in cardiometabolic syndrome.DPP-4 inhibition improves early mortality, β cell function, and adipose tissue inflammation in db/db mice fed a diet containing sucrose and linoleic acid.12/15-lipoxygenase expressed in non-epithelial cells causes airway epithelial injury in asthma.12/15-Lipoxygenase mediates high-fat diet-induced endothelial tight junction disruption and monocyte transmigration: a new role for 15(S)-hydroxyeicosatetraenoic acid in endothelial cell dysfunctionNeuronatin: a new inflammation gene expressed on the aortic endothelium of diabetic mice.Role of Src tyrosine kinase in the atherogenic effects of the 12/15-lipoxygenase pathway in vascular smooth muscle cellsRole of the lysine-specific demethylase 1 in the proinflammatory phenotype of vascular smooth muscle cells of diabetic mice.Effects of vitamin E on mitochondrial dysfunction and asthma features in an experimental allergic murine model.Vascular endothelial tight junctions and barrier function are disrupted by 15(S)-hydroxyeicosatetraenoic acid partly via protein kinase C ε-mediated zona occludens-1 phosphorylation at threonine 770/772.The transcription factor CREB enhances interleukin-17A production and inflammation in a mouse model of atherosclerosisTargeting of 12/15-Lipoxygenase in retinal endothelial cells, but not in monocytes/macrophages, attenuates high glucose-induced retinal leukostasis.Class A scavenger receptor-mediated macrophage adhesion requires coupling of calcium-independent phospholipase A(2) and 12/15-lipoxygenase to Rac and Cdc42 activation.Regio- and stereo-chemical oxidation of linoleic acid by human myoglobin and hydrogen peroxide: Tyr(103) affects rate and product distribution.Cardiac 12/15 lipoxygenase-induced inflammation is involved in heart failure.Lipoxygenase and prostaglandin G/H synthase cascades in cardiovascular disease.Glucose regulates interleukin-8 production in aortic endothelial cells through activation of the p38 mitogen-activated protein kinase pathway in diabetes.
P2860
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P2860
Increased production of 12/15 lipoxygenase eicosanoids accelerates monocyte/endothelial interactions in diabetic db/db mice.
description
2003 nî lūn-bûn
@nan
2003 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Increased production of 12/15 ...... ctions in diabetic db/db mice.
@ast
Increased production of 12/15 ...... ctions in diabetic db/db mice.
@en
type
label
Increased production of 12/15 ...... ctions in diabetic db/db mice.
@ast
Increased production of 12/15 ...... ctions in diabetic db/db mice.
@en
prefLabel
Increased production of 12/15 ...... ctions in diabetic db/db mice.
@ast
Increased production of 12/15 ...... ctions in diabetic db/db mice.
@en
P2093
P2860
P356
P1476
Increased production of 12/15 ...... ctions in diabetic db/db mice.
@en
P2093
Catherine C Hedrick
Kelly B Reilly
Melissa E Hatley
Suseela Srinivasan
P2860
P304
25369-25375
P356
10.1074/JBC.M301175200
P407
P577
2003-05-06T00:00:00Z