Sequence and conformational specificity in substrate recognition: several human Kunitz protease inhibitor domains are specific substrates of mesotrypsin.
about
Mesotrypsin Has Evolved Four Unique Residues to Cleave Trypsin Inhibitors as SubstratesAn Acrobatic Substrate Metamorphosis Reveals a Requirement for Substrate Conformational Dynamics in Trypsin Proteolysis.Small molecule inhibitors of mesotrypsin from a structure-based docking screen.Mesotrypsin Signature Mutation in a Chymotrypsin C (CTRC) Variant Associated with Chronic Pancreatitis.Combinatorial protein engineering of proteolytically resistant mesotrypsin inhibitors as candidates for cancer therapyEpithelial expression and function of trypsin-3 in irritable bowel syndrome.The Kunitz Domain I of Hepatocyte Growth Factor Activator Inhibitor-2 Inhibits Matriptase Activity and Invasive Ability of Human Prostate Cancer Cells.Pre-equilibrium competitive library screening for tuning inhibitor association rate and specificity toward serine proteases.HAI-2 stabilizes, inhibits and regulates SEA-cleavage-dependent secretory transport of matriptase.
P2860
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P2860
Sequence and conformational specificity in substrate recognition: several human Kunitz protease inhibitor domains are specific substrates of mesotrypsin.
description
2014 nî lūn-bûn
@nan
2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Sequence and conformational sp ...... fic substrates of mesotrypsin.
@ast
Sequence and conformational sp ...... fic substrates of mesotrypsin.
@en
type
label
Sequence and conformational sp ...... fic substrates of mesotrypsin.
@ast
Sequence and conformational sp ...... fic substrates of mesotrypsin.
@en
prefLabel
Sequence and conformational sp ...... fic substrates of mesotrypsin.
@ast
Sequence and conformational sp ...... fic substrates of mesotrypsin.
@en
P2093
P2860
P356
P1476
Sequence and conformational sp ...... fic substrates of mesotrypsin.
@en
P2093
Alexandra Hockla
Alexei S Soares
Benjamin J Madden
Devon Pendlebury
Rachel D Henin
Ruiying Wang
P2860
P304
32783-32797
P356
10.1074/JBC.M114.609560
P407
P577
2014-10-09T00:00:00Z