A synonymous polymorphism in a common MDR1 (ABCB1) haplotype shapes protein function.
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The effect of ABCB1 polymorphisms on the outcome of breast cancer treatmentThe role of reduced intracellular concentrations of active drugs in the lack of response to anticancer chemotherapySystematic review: diet-gene interactions and the risk of colorectal cancerPharmacogenomics of Drug Metabolizing Enzymes and Transporters: Relevance to Precision MedicineAdvances in the molecular detection of ABC transporters involved in multidrug resistance in cancerbba, a synthetic derivative of 23-hydroxybutulinic acid, reverses multidrug resistance by inhibiting the efflux activity of MRP7 (ABCC10)Genetic variations in radiation and chemotherapy drug action pathways and survival in locoregionally advanced nasopharyngeal carcinoma treated with chemoradiotherapyAssociation between XPF polymorphisms and cancer risk: a meta-analysis.Polymorphisms in the xenobiotic transporter Multidrug Resistance 1 (MDR1) and interaction with meat intake in relation to risk of colorectal cancer in a Danish prospective case-cohort studyPrognostic and predictive factors in patients with metastatic or recurrent cervical cancer treated with platinum-based chemotherapy.The maximum tolerated dose and biologic effects of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP) in combination with irinotecan for patients with refractory solid tumors.Laying a solid foundation for Manhattan--'setting the functional basis for the post-GWAS era'.Natural selection retains overrepresented out-of-frame stop codons against frameshift peptides in prokaryotes.The skin cancer chemotherapeutic agent ingenol-3-angelate (PEP005) is a substrate for the epidermal multidrug transporter (ABCB1) and targets tumor vasculature.A novel application of pattern recognition for accurate SNP and indel discovery from high-throughput data: targeted resequencing of the glucocorticoid receptor co-chaperone FKBP5 in a Caucasian populationInherited variation in the ATP-binding cassette transporter ABCB1 and survival after chemotherapy for stage III-IV lung cancerAssociation of MDR1 gene SNPs and haplotypes with the tacrolimus dose requirements in Han Chinese liver transplant recipients.Effect of ABCB1 C3435T polymorphism on docetaxel pharmacokinetics according to menopausal status in breast cancer patients.Domperidone treatment for gastroparesis: demographic and pharmacogenetic characterization of clinical efficacy and side-effects.Transcriptional enhancers in protein-coding exons of vertebrate developmental genes.Functional rescue of a misfolded eukaryotic ATP-binding cassette transporter by domain replacement.CYP3A5 genotype impacts maraviroc concentrations in healthy volunteers.Complex polymorphisms in the Plasmodium falciparum multidrug resistance protein 2 gene and its contribution to antimalarial response.Interactions between meat intake and genetic variation in relation to colorectal cancer.Population pharmacokinetics of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (Triapine®) in cancer patients.Incorporation of ABCB1-mediated transport into a physiologically-based pharmacokinetic model of docetaxel in mice.Very important pharmacogene summary: ABCB1 (MDR1, P-glycoprotein)Efflux transporters- and cytochrome P-450-mediated interactions between drugs of abuse and antiretrovirals.Chemokine (C-C motif) receptor 5 -2459 genotype in patients receiving highly active antiretroviral therapy: race-specific influence on virologic successABC transporters: unvalidated therapeutic targets in cancer and the CNSInfluence of ATP-binding cassette polymorphisms on neurological outcome after traumatic brain injury.Possible association of ABCB1:c.3435T>C polymorphism with high-density-lipoprotein-cholesterol response to statin treatment--a pilot study.ABCB1 (rs1128503) polymorphism and response to chemotherapy in patients with malignant tumors-evidences from a meta-analysis.Comparative description of haplotype structure and genetic diversity of MDR1 (ABCB1) in HIV-positive and HIV-negative populations.Acyclovir achieves a lower concentration in African HIV-seronegative, herpes simplex virus 2-seropositive women than in non-African populations.Tyrosine kinase inhibitors as modulators of ABC transporter-mediated drug resistance.Drug resistance: still a daunting challenge to the successful treatment of AML.Trametinib modulates cancer multidrug resistance by targeting ABCB1 transporterA case-control study of innate immunity pathway gene polymorphisms in Puerto Ricans reveals association of toll-like receptor 2 +596 variant with asthmaImproving cancer chemotherapy with modulators of ABC drug transporters.
P2860
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P2860
A synonymous polymorphism in a common MDR1 (ABCB1) haplotype shapes protein function.
description
2009 nî lūn-bûn
@nan
2009 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մարտին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
A synonymous polymorphism in a common MDR1 (ABCB1) haplotype shapes protein function.
@ast
A synonymous polymorphism in a common MDR1 (ABCB1) haplotype shapes protein function.
@en
type
label
A synonymous polymorphism in a common MDR1 (ABCB1) haplotype shapes protein function.
@ast
A synonymous polymorphism in a common MDR1 (ABCB1) haplotype shapes protein function.
@en
prefLabel
A synonymous polymorphism in a common MDR1 (ABCB1) haplotype shapes protein function.
@ast
A synonymous polymorphism in a common MDR1 (ABCB1) haplotype shapes protein function.
@en
P2860
P1476
A synonymous polymorphism in a common MDR1 (ABCB1) haplotype shapes protein function.
@en
P2093
King Leung Fung
Michael M Gottesman
P2860
P304
P356
10.1016/J.BBAPAP.2009.02.014
P407
P577
2009-03-11T00:00:00Z