5-Lipoxygenase, but not 12/15-lipoxygenase, contributes to degeneration of retinal capillaries in a mouse model of diabetic retinopathy. - sprookjes - yvandenbroek - TriplyDB

5-Lipoxygenase, but not 12/15-lipoxygenase, contributes to degeneration of retinal capillaries in a mouse model of diabetic retinopathy.

5-Lipoxygenase, but not 12/15-lipoxygenase, contributes to degeneration of retinal capillaries in a mouse model of diabetic retinopathy.

http://www.wikidata.org/entity/Q30393975

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Neuroprotection as a Therapeutic Target for Diabetic Retinopathy Leukotriene B4 as a Potential Therapeutic Target for the Treatment of Metabolic Disorders Lipid mediators are critical in resolving inflammation: a review of the emerging roles of eicosanoids in diabetes mellitus Functional and pathological roles of the 12- and 15-lipoxygenases Evidence for activation of inflammatory lipoxygenase pathways in visceral adipose tissue of obese Zucker rats.NRF2 plays a protective role in diabetic retinopathy in mice Increased synthesis of leukotrienes in the mouse model of diabetic retinopathy.Profile of lipid and protein autacoids in diabetic vitreous correlates with the progression of diabetic retinopathy.Comparison of three strains of diabetic rats with respect to the rate at which retinopathy and tactile allodynia develop.Different roles of 12/15-lipoxygenase in diabetic large and small fiber peripheral and autonomic neuropathies.Dysregulated heme oxygenase-ferritin system in pterygium pathogenesis.Validation of structural and functional lesions of diabetic retinopathy in mice Diabetic retinopathy: targeting vasoregression Minireview: 12-Lipoxygenase and Islet β-Cell Dysfunction in Diabetes.Increased expression and activity of 12-lipoxygenase in oxygen-induced ischemic retinopathy and proliferative diabetic retinopathy: implications in retinal neovascularization.12/15-Lipoxygenase-derived lipid metabolites induce retinal endothelial cell barrier dysfunction: contribution of NADPH oxidase Role of 12/15-lipoxygenase in nitrosative stress and peripheral prediabetic and diabetic neuropathies Retinal upregulation of inflammatory and proangiogenic markers in a model of neonatal diabetic rats fed on a high-fat-diet.Multiparametric and semiquantitative scoring systems for the evaluation of mouse model histopathology--a systematic review.MyD88-dependent pathways in leukocytes affect the retina in diabetes.CD40 promotes the development of early diabetic retinopathy in mice Elevated level of pro-inflammatory eicosanoids and EPC dysfunction in diabetic patients with cardiac ischemia Immunohistochemical localization of key arachidonic acid metabolism enzymes during fracture healing in mice.A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase.Role of the receptor for advanced glycation endproducts (RAGE) in retinal vasodegenerative pathology during diabetes in mice.Adrenergic and serotonin receptors affect retinal superoxide generation in diabetic mice: relationship to capillary degeneration and permeability.Imbalances in Mobilization and Activation of Pro-Inflammatory and Vascular Reparative Bone Marrow-Derived Cells in Diabetic Retinopathy.Retinylamine Benefits Early Diabetic Retinopathy in Mice Systemic Retinaldehyde Treatment Corrects Retinal Oxidative Stress, Rod Dysfunction, and Impaired Visual Performance in Diabetic Mice Diabetic Retinopathy: Retina-Specific Methods for Maintenance of Diabetic Rodents and Evaluation of Vascular Histopathology and Molecular Abnormalities.ω-3 and ω-6 long-chain PUFAs and their enzymatic metabolites in neovascular eye diseases.Marrow-derived cells regulate the development of early diabetic retinopathy and tactile allodynia in mice Leukocytes regulate retinal capillary degeneration in the diabetic mouse via generation of leukotrienes.Examining the role of lipid mediators in diabetic retinopathy.Lymphoblastoid Cell Lines as a Tool to Study Inter-Individual Differences in the Response to Glucose Photoreceptor cells are major contributors to diabetes-induced oxidative stress and local inflammation in the retina Photoreceptor Cells Influence Retinal Vascular Degeneration in Mouse Models of Retinal Degeneration and Diabetes Animal models of diabetic retinopathy: summary and comparison.Nrf2 has a protective role against neuronal and capillary degeneration in retinal ischemia-reperfusion injury.Inflammation in diabetic retinopathy.

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P2860

5-Lipoxygenase, but not 12/15-lipoxygenase, contributes to degeneration of retinal capillaries in a mouse model of diabetic retinopathy.

http://www.wikidata.org/entity/Q30393975

description

2008 nî lūn-bûn

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2008 թուականի Մարտին հրատարակուած գիտական յօդուած

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5-Lipoxygenase, but not 12/15- ...... model of diabetic retinopathy.

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5-Lipoxygenase, but not 12/15- ...... model of diabetic retinopathy.

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5-Lipoxygenase, but not 12/15- ...... model of diabetic retinopathy.

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5-Lipoxygenase, but not 12/15- ...... model of diabetic retinopathy.

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Ramaprasad Talahalli

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Rose A Gubitosi-Klug

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Timothy S Kern

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Yunpeng Du

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P2860

Hyperglycemia increases mitochondrial superoxide in retina and retinal cells

Pharmacological inhibition of diabetic retinopathy: aminoguanidine and aspirin

Salicylate-based anti-inflammatory drugs inhibit the early lesion of diabetic retinopathy

Pharmacotherapy of diseases mediated by 5-lipoxygenase pathway eicosanoids

The 5 lipoxygenase system in the vasculature: emerging role in health and disease

Prevention of leukostasis and vascular leakage in streptozotocin-induced diabetic retinopathy via intercellular adhesion molecule-1 inhibition

Expression of 5-lipoxygenase in pulmonary artery endothelial cells

Leukocyte-mediated endothelial cell injury and death in the diabetic retina

Blockade of 12-lipoxygenase expression protects cortical neurons from apoptosis induced by beta-amyloid peptide

Effects of silencing leukocyte-type 12/15-lipoxygenase using short interfering RNAs

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