Diacylglycerol kinase α is a critical signaling node and novel therapeutic target in glioblastoma and other cancers. - sprookjes - yvandenbroek - TriplyDB

Diacylglycerol kinase α is a critical signaling node and novel therapeutic target in glioblastoma and other cancers.

Diacylglycerol kinase α is a critical signaling node and novel therapeutic target in glioblastoma and other cancers.

http://www.wikidata.org/entity/Q30412090

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Diacylglycerol Kinases: Shaping Diacylglycerol and Phosphatidic Acid Gradients to Control Cell Polarity Diacylglycerol Kinases as Emerging Potential Drug Targets for a Variety of Diseases: An Update Diacylglycerol Kinases (DGKs): Novel Targets for Improving T Cell Activity in Cancer Dual activities of ritanserin and R59022 as DGKα inhibitors and serotonin receptor antagonists.Molecular Pathways: Targeting Diacylglycerol Kinase Alpha in Cancer Micro-masters of glioblastoma biology and therapy: increasingly recognized roles for microRNAs.A miR-297/hypoxia/DGK-α axis regulating glioblastoma survival.The diacylglycerol kinase α/atypical PKC/β1 integrin pathway in SDF-1α mammary carcinoma invasiveness.Phospholipase D and the maintenance of phosphatidic acid levels for regulation of mammalian target of rapamycin (mTOR)Diacylglycerol kinase α promotes 3D cancer cell growth and limits drug sensitivity through functional interaction with Src.Inhibition of diacylglycerol kinase α restores restimulation-induced cell death and reduces immunopathology in XLP-1.The genome of the myxosporean Thelohanellus kitauei shows adaptations to nutrient acquisition within its fish host.A novel diacylglycerol kinase α-selective inhibitor, CU-3, induces cancer cell apoptosis and enhances immune response.BIM and mTOR expression levels predict outcome to erlotinib in EGFR-mutant non-small-cell lung cancer Epigenetic regulation of diacylglycerol kinase alpha promotes radiation-induced fibrosis.Control of fluxes in metabolic networks.Transcription factor Reb1p regulates DGK1-encoded diacylglycerol kinase and lipid metabolism in Saccharomyces cerevisiae.Decreased LIPF expression is correlated with DGKA and predicts poor outcome of gastric cancer Monitoring Phosphatidic Acid Signaling in Breast Cancer Cells Using Genetically Encoded Biosensors.miR-17/20 Controls Prolyl Hydroxylase 2 (PHD2)/Hypoxia-Inducible Factor 1 (HIF1) to Regulate Pulmonary Artery Smooth Muscle Cell Proliferation.Predicting resistance by selection of signaling pathways.Epigenetic silencing of diacylglycerol kinase gamma in colorectal cancer.Orchestrating cellular signaling pathways-the cellular "conductor" protein tyrosine phosphatase interacting protein 51 (PTPIP51).DGK-α: A Checkpoint in Cancer-Mediated Immuno-Inhibition and Target for Immunotherapy.Modulated DISP3/PTCHD2 expression influences neural stem cell fate decisions The Ligand Binding Landscape of Diacylglycerol Kinases.Targeting the mesenchymal subtype in glioblastoma and other cancers via inhibition of diacylglycerol kinase alpha.Id2 Collaborates with Id3 To Suppress Invariant NKT and Innate-like Tumors.Ritanserin, a novel agent targeting the mesenchymal subtype of glioblastomas.Loss of Diacylglycerol Kinase-Ζ Inhibits Cell Proliferation and Survival in Human Gliomas.NK-cell dysfunction in human renal carcinoma reveals diacylglycerol kinase as key regulator and target for therapeutic intervention.Expression and purification of human diacylglycerol kinase α from baculovirus-infected insect cells for structural studies

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Diacylglycerol kinase α is a critical signaling node and novel therapeutic target in glioblastoma and other cancers.

http://www.wikidata.org/entity/Q30412090

description

2013 nî lūn-bûn

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2013 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2013 թվականի ապրիլին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

Diacylglycerol kinase α is a c ...... lioblastoma and other cancers.

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Diacylglycerol kinase α is a c ...... lioblastoma and other cancers.

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Diacylglycerol kinase α is a c ...... lioblastoma and other cancers.

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Diacylglycerol kinase α is a c ...... lioblastoma and other cancers.

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Diacylglycerol kinase α is a c ...... lioblastoma and other cancers.

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Diacylglycerol kinase α is a c ...... lioblastoma and other cancers.

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Cancer Discovery

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Diacylglycerol kinase α is a c ...... lioblastoma and other cancers.

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Aizhen Xiao

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Benjamin A Kefas

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Benjamin W Purow

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Charli L Dominguez

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Desiree H Floyd

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Gabriela Mustata Wilson

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Garrett R Mullins

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Jae K Lee

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Melissa N Yacur

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Roger Abounader

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P2860

A simple method for the isolation and purification of total lipides from animal tissues

HIF-1: mediator of physiological and pathophysiological responses to hypoxia

Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics

Activation of alpha-diacylglycerol kinase is critical for the mitogenic properties of anaplastic lymphoma kinase

Activation of diacylglycerol kinase alpha is required for VEGF-induced angiogenic signaling in vitro

Diacylglycerol kinases: at the hub of cell signalling

The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data

Diacylglycerol kinase alpha suppresses tumor necrosis factor-alpha-induced apoptosis of human melanoma cells through NF-kappaB activation

Modulation of the mammalian target of rapamycin pathway by diacylglycerol kinase-produced phosphatidic acid

Selectivity of the diacylglycerol kinase inhibitor 3-[2-(4-[bis-(4-fluorophenyl)methylene]-1-piperidinyl)ethyl]-2, 3-dihydro-2-thioxo-4(1H)quinazolinone (R59949) among diacylglycerol kinase subtypes

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