T-705 (favipiravir) induces lethal mutagenesis in influenza A H1N1 viruses in vitro
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The ambiguous base-pairing and high substrate efficiency of T-705 (Favipiravir) Ribofuranosyl 5'-triphosphate towards influenza A virus polymeraseExtinction of hepatitis C virus by ribavirin in hepatoma cells involves lethal mutagenesisPeramivir: A Novel Intravenous Neuraminidase Inhibitor for Treatment of Acute Influenza InfectionsCurrent Landscape of Antiviral Drug DiscoveryAddressing Therapeutic Options for Ebola Virus Infection in Current and Future OutbreaksEvaluation of antiviral efficacy of ribavirin, arbidol, and T-705 (favipiravir) in a mouse model for Crimean-Congo hemorrhagic feverThe Influenza Virus Polymerase Complex: An Update on Its Structure, Functions, and Significance for Antiviral Drug DesignCoronaviruses lacking exoribonuclease activity are susceptible to lethal mutagenesis: evidence for proofreading and potential therapeuticsImpact of Respiratory Virus Infections in Exacerbation of Acute and Chronic Rhinosinusitis.Synergistic combinations of favipiravir and oseltamivir against wild-type pandemic and oseltamivir-resistant influenza A virus infections in mice.A Novel Endonuclease Inhibitor Exhibits Broad-Spectrum Anti-Influenza Virus Activity In VitroInfluenza antivirals currently in late-phase clinical trial.Emerging antiviral strategies to interfere with influenza virus entry.Molecular and Functional Bases of Selection against a Mutation Bias in an RNA Virus.Antiviral drug resistance as an adaptive processTautomerism provides a molecular explanation for the mutagenic properties of the anti-HIV nucleoside 5-aza-5,6-dihydro-2'-deoxycytidineGeneration and characterization of influenza A viruses with altered polymerase fidelity.Favipiravir (T-705), a novel viral RNA polymerase inhibitor.Two-dimensional IR spectroscopy of the anti-HIV agent KP1212 reveals protonated and neutral tautomers that influence pH-dependent mutagenicity.Alterations in favipiravir (T-705) pharmacokinetics and biodistribution in a hamster model of viral hemorrhagic fever.Lack of mutational hot spots during decitabine-mediated HIV-1 mutagenesisLethal Mutagenesis of Hepatitis C Virus Induced by Favipiravir.The Environmental Pollutant Cadmium Promotes Influenza Virus Replication in MDCK Cells by Altering Their Redox StateCombinations of Oseltamivir and T-705 Extend the Treatment Window for Highly Pathogenic Influenza A(H5N1) Virus Infection in MiceAntiviral Activity of Favipiravir (T-705) against a Broad Range of Paramyxoviruses In Vitro and against Human Metapneumovirus in Hamsters.The neuraminidase inhibitor oseltamivir is effective against A/Anhui/1/2013 (H7N9) influenza virus in a mouse model of acute respiratory distress syndrome.A novel benzo-heterocyclic amine derivative N30 inhibits influenza virus replication by depression of Inosine-5'-Monophospate Dehydrogenase activity.Progress towards the prevention and treatment of norovirus infections.Development of Small-Molecule Antivirals for Ebola.Efficacy of Favipiravir Alone and in Combination With Ribavirin in a Lethal, Immunocompetent Mouse Model of Lassa Fever.Extinction of West Nile virus by Favipiravir through lethal mutagenesis.Epistatic Interactions within the Influenza A Virus Polymerase Complex Mediate Mutagen Resistance and Replication Fidelity.A novel twelve class fluctuation test reveals higher than expected mutation rates for influenza A viruses.Biochemical Evaluation of the Inhibition Properties of Favipiravir and 2'-C-Methyl-Cytidine Triphosphates against Human and Mouse Norovirus RNA Polymerases.Effective lethal mutagenesis of influenza virus by three nucleoside analogs.Therapeutics for postexposure treatment of Ebola virus infection.An experimental evaluation of drug-induced mutational meltdown as an antiviral treatment strategy.The prediction of virus mutation using neural networks and rough set techniques.Favipiravir (T-705), a broad spectrum inhibitor of viral RNA polymerase.Repurposed Therapeutic Agents Targeting the Ebola Virus: A Systematic Review.
P2860
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P2860
T-705 (favipiravir) induces lethal mutagenesis in influenza A H1N1 viruses in vitro
description
2013 nî lūn-bûn
@nan
2013 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2013年の論文
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2013年学术文章
@wuu
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
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2013年學術文章
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name
T-705 (favipiravir) induces lethal mutagenesis in influenza A H1N1 viruses in vitro
@ast
T-705 (favipiravir) induces lethal mutagenesis in influenza A H1N1 viruses in vitro
@en
type
label
T-705 (favipiravir) induces lethal mutagenesis in influenza A H1N1 viruses in vitro
@ast
T-705 (favipiravir) induces lethal mutagenesis in influenza A H1N1 viruses in vitro
@en
prefLabel
T-705 (favipiravir) induces lethal mutagenesis in influenza A H1N1 viruses in vitro
@ast
T-705 (favipiravir) induces lethal mutagenesis in influenza A H1N1 viruses in vitro
@en
P2093
P2860
P50
P356
P1433
P1476
T-705 (favipiravir) induces lethal mutagenesis in influenza A H1N1 viruses in vitro
@en
P2093
Henju Marjuki
Jianling Armstrong
Sook-San Wong
Tatiana Baranovich
P2860
P304
P356
10.1128/JVI.02346-12
P577
2013-01-16T00:00:00Z