Insulin-regulated aminopeptidase is a key regulator of GLUT4 trafficking by controlling the sorting of GLUT4 from endosomes to specialized insulin-regulated vesicles
about
Insulin responsiveness of glucose transporter 4 in 3T3-L1 cells depends on the presence of sortilinSingle point mutations result in the miss-sorting of Glut4 to a novel membrane compartment associated with stress granule proteins.Loss of AS160 Akt substrate causes Glut4 protein to accumulate in compartments that are primed for fusion in basal adipocytes.The first luminal loop confers insulin responsiveness to glucose transporter 4.The ubiquitin regulatory X (UBX) domain-containing protein TUG regulates the p97 ATPase and resides at the endoplasmic reticulum-golgi intermediate compartment.Coordinated Regulation of Vasopressin Inactivation and Glucose Uptake by Action of TUG Protein in Muscle.The role of insulin-regulated aminopeptidase in MHC class I antigen presentation.The Axin/TNKS complex interacts with KIF3A and is required for insulin-stimulated GLUT4 translocationRole of monosaccharide transport proteins in carbohydrate assimilation, distribution, metabolism, and homeostasis.The Rab GTPase-activating protein TBC1D4/AS160 contains an atypical phosphotyrosine-binding domain that interacts with plasma membrane phospholipids to facilitate GLUT4 trafficking in adipocytes.SEC16A is a RAB10 effector required for insulin-stimulated GLUT4 trafficking in adipocytes.Specialized sorting of GLUT4 and its recruitment to the cell surface are independently regulated by distinct Rabs.High glucose activates the alternative ACE2/Ang-(1-7)/Mas and APN/Ang IV/IRAP RAS axes in pancreatic β-cells.The effects of exercise training and caloric restriction on the cardiac oxytocin natriuretic peptide system in the diabetic mouse.The sugar is sIRVed: sorting Glut4 and its fellow travelers.A proteolytic pathway that controls glucose uptake in fat and muscle.Novel RAAS agonists and antagonists: clinical applications and controversies.Alternative renin-angiotensin system pathways in adipose tissue and their role in the pathogenesis of obesity.Molecular basis of insulin-responsive GLUT4 trafficking systems revealed by single molecule imaging.Presence and regulation of insulin-regulated aminopeptidase in mouse macrophages.Effect of troxerutin on insulin signaling molecules in the gastrocnemius muscle of high fat and sucrose-induced type-2 diabetic adult male rat.
P2860
Q28297062-657B5B3F-C2C3-4E38-B7B3-6A65446B6080Q34849061-91401890-29A4-4118-A4CD-222FEB710080Q35128107-A808FFAE-E6C9-4E58-B2EB-B55E21E10812Q35790922-323E18B3-C37E-4E8B-9F0B-C45834367271Q35838940-7E2AA2B0-2683-4404-A556-34FACC5735E1Q35860779-44DE530A-1B9F-44A1-8917-92D868A6091BQ35928365-12C51193-8682-4DBE-A8F7-A97DCFC6A3AFQ36137822-BD953D86-AE01-47FC-8D63-A961B681E80FQ36197966-FD21DB28-739E-447E-A3A6-F853D7391CBFQ36435173-451D9128-074A-44A7-832C-E6832DF64F48Q37063757-6A56246C-0CDC-4180-9F77-396FCEC066FBQ37098751-12951FE1-6E6A-4B2F-BE44-78A5453C934BQ37265803-CAB09840-D1DA-43B6-96D2-CD49A52DA54BQ37588114-52E10A04-02DE-4BDE-8C23-B22CCB312007Q37838504-4F99D364-ADF0-4A41-8FBF-1744FA515237Q38151511-6D6F8109-9917-4F49-B901-4519DD60E899Q38349798-3A3D5217-4A40-443D-A28F-A5F22E3ED12EQ39035728-13A37173-76E6-449B-9E23-6B0BEB1E6DFFQ42805723-4C3FA7A0-ACC8-4E00-AC06-ABE490ACDD55Q42806618-8F49A7C0-B97E-4250-9AA7-4F86D8768C84Q51321708-D1187C80-396B-4F2A-8F18-0ABC5D8A8283
P2860
Insulin-regulated aminopeptidase is a key regulator of GLUT4 trafficking by controlling the sorting of GLUT4 from endosomes to specialized insulin-regulated vesicles
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Insulin-regulated aminopeptida ...... zed insulin-regulated vesicles
@ast
Insulin-regulated aminopeptida ...... zed insulin-regulated vesicles
@en
type
label
Insulin-regulated aminopeptida ...... zed insulin-regulated vesicles
@ast
Insulin-regulated aminopeptida ...... zed insulin-regulated vesicles
@en
prefLabel
Insulin-regulated aminopeptida ...... zed insulin-regulated vesicles
@ast
Insulin-regulated aminopeptida ...... zed insulin-regulated vesicles
@en
P2093
P2860
P356
P1476
Insulin-regulated aminopeptida ...... zed insulin-regulated vesicles
@en
P2093
Dorothee Molle
Susanna R Keller
Timothy E McGraw
P2860
P304
P356
10.1091/MBC.E10-02-0158
P577
2010-04-21T00:00:00Z