Insulinotropic treatments exacerbate metabolic syndrome in mice lacking MeCP2 function. - sprookjes - yvandenbroek - TriplyDB

Insulinotropic treatments exacerbate metabolic syndrome in mice lacking MeCP2 function.

Insulinotropic treatments exacerbate metabolic syndrome in mice lacking MeCP2 function.

http://www.wikidata.org/entity/Q30435678

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Anaplerotic triheptanoin diet enhances mitochondrial substrate use to remodel the metabolome and improve lifespan, motor function, and sociability in MeCP2-null mice DNA modifications: function and applications in normal and disease States Targeted pharmacological treatment of autism spectrum disorders: fragile X and Rett syndromes Rett Syndrome: Reaching for Clinical Trials A protocol for evaluation of Rett Syndrome symptom improvement by metabolic modulators in Mecp2-mutant mice.Safety, pharmacokinetics, and preliminary assessment of efficacy of mecasermin (recombinant human IGF-1) for the treatment of Rett syndrome.Functional recovery with recombinant human IGF1 treatment in a mouse model of Rett Syndrome.Dendritic spine dysgenesis in Rett syndrome.Treatment of cardiac arrhythmias in a mouse model of Rett syndrome with Na+-channel-blocking antiepileptic drugs.Rett syndrome like phenotypes in the R255X Mecp2 mutant mouse are rescued by MECP2 transgene MeCP2 Related Studies Benefit from the Use of CD1 as Genetic Background.PTP1B inhibition suggests a therapeutic strategy for Rett syndrome PTP1B: a new therapeutic target for Rett syndrome Wild-type microglia do not reverse pathology in mouse models of Rett syndrome Progressive Changes in a Distributed Neural Circuit Underlie Breathing Abnormalities in Mice Lacking MeCP2.Loss of MeCP2 function is associated with distinct gene expression changes in the striatum Systemic Radical Scavenger Treatment of a Mouse Model of Rett Syndrome: Merits and Limitations of the Vitamin E Derivative Trolox Alterations in the carnitine cycle in a mouse model of Rett syndrome.A role for metabolism in Rett syndrome pathogenesis: New clinical findings and potential treatment targets.Methyl-CpG-Binding Protein (MBD) Family: Epigenomic Read-Outs Functions and Roles in Tumorigenesis and Psychiatric Diseases.Genetic and Pharmacological Reversibility of Phenotypes in Mouse Models of Autism Spectrum Disorder.Neurotrophic Factors in Mouse Models of Autism Spectrum Disorder: Focus on BDNF and IGF-1.RNA sequencing and proteomics approaches reveal novel deficits in the cortex of Mecp2-deficient mice, a model for Rett syndrome.Genetic rodent models of brain disorders: Perspectives on experimental approaches and therapeutic strategies.Early motor phenotype detection in a female mouse model of Rett syndrome is improved by cross-fostering.

P2860

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P2860

Insulinotropic treatments exacerbate metabolic syndrome in mice lacking MeCP2 function.

http://www.wikidata.org/entity/Q30435678

description

2013 nî lūn-bûn

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2013 թուականի Մարտին հրատարակուած գիտական յօդուած

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2013 թվականի մարտին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

@zh-hk

2013年論文

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2013年論文

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2013年论文

@wuu

name

Insulinotropic treatments exacerbate metabolic syndrome in mice lacking MeCP2 function.

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Insulinotropic treatments exacerbate metabolic syndrome in mice lacking MeCP2 function.

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type

label

Insulinotropic treatments exacerbate metabolic syndrome in mice lacking MeCP2 function.

@ast

Insulinotropic treatments exacerbate metabolic syndrome in mice lacking MeCP2 function.

@en

prefLabel

Insulinotropic treatments exacerbate metabolic syndrome in mice lacking MeCP2 function.

@ast

Insulinotropic treatments exacerbate metabolic syndrome in mice lacking MeCP2 function.

@en

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Human Molecular Genetics

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Insulinotropic treatments exacerbate metabolic syndrome in mice lacking MeCP2 function.

@en

P2093

Christopher A Chapleau

http://www.w3.org/2001/XMLSchema#string

E Melissa Arvide

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Friedrich Metzger

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Jeffrey L Neul

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Manaswini Sivaramakrishnan

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Meagan R Pitcher

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Stefanie Saenger

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P2860

Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

Rett syndrome: revised diagnostic criteria and nomenclature

Pathogenesis of lethal cardiac arrhythmias in Mecp2 mutant mice: implication for therapy in Rett syndrome

MeCP2, a key contributor to neurological disease, activates and represses transcription

Partial reversal of Rett Syndrome-like symptoms in MeCP2 mutant mice

A duplication CNV that conveys traits reciprocal to metabolic syndrome and protects against diet-induced obesity in mice and men

A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome

A partial loss of function allele of methyl-CpG-binding protein 2 predicts a human neurodevelopmental syndrome

Bdnf overexpression in hippocampal neurons prevents dendritic atrophy caused by Rett-associated MECP2 mutations

Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice

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2626-2633

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scholarly article

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10.1093/HMG/DDT111

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13

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22

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Lucas Pozzo-miller

Andreas Hoeflich

Christopher S. Ward

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2013-03-05T00:00:00Z

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235796383

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23462290

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metabolic syndrome

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3674803

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