Sphingosine-1-phosphate induces an antiinflammatory phenotype in macrophages. - sprookjes - yvandenbroek - TriplyDB

Sphingosine-1-phosphate induces an antiinflammatory phenotype in macrophages.

Sphingosine-1-phosphate induces an antiinflammatory phenotype in macrophages.

http://www.wikidata.org/entity/Q30436091

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Identification of a novel macrophage phenotype that develops in response to atherogenic phospholipids via Nrf2.G2A deficiency in mice promotes macrophage activation and atherosclerosis.Modulation of Intrathymic Sphingosine-1-Phosphate Levels Promotes Escape of Immature Thymocytes to the Periphery with a Potential Proinflammatory Role in Chagas Disease Sphingolipid signaling in metabolic disorders The adipokine/ceramide axis: key aspects of insulin sensitization Sphingosine-1 Phosphate: A New Modulator of Immune Plasticity in the Tumor Microenvironment FTY720 reduces post-ischemic brain lymphocyte influx but does not improve outcome in permanent murine cerebral ischemia The promotion of mandibular defect healing by the targeting of S1P receptors and the recruitment of alternatively activated macrophages.Phenotypic modulation of macrophages in response to plaque lipids.Local delivery of FTY720 accelerates cranial allograft incorporation and bone formation.International Union of Basic and Clinical Pharmacology. LXXVIII. Lysophospholipid receptor nomenclature.Myeloid cell-specific serine palmitoyltransferase subunit 2 haploinsufficiency reduces murine atherosclerosis.The efficacy of activated protein C in murine endotoxemia is dependent on integrin CD11b Francisella tularensis LVS induction of prostaglandin biosynthesis by infected macrophages requires specific host phospholipases and lipid phosphatases Sphingosine-1-phosphate receptor-2 deficiency leads to inhibition of macrophage proinflammatory activities and atherosclerosis in apoE-deficient mice Modulation of chemokines and allergic airway inflammation by selective local sphingosine-1-phosphate receptor 1 agonism in lungs The heterogenic properties of monocytes/macrophages and neutrophils in inflammatory response in diabetes.Hematopoietic sphingosine 1-phosphate lyase deficiency decreases atherosclerotic lesion development in LDL-receptor deficient mice Plasma sphingosine-1-phosphate is elevated in obesity Role of sphingosine-1-phosphate (S1P) and S1P receptor 2 in the phagocytosis of Cryptococcus neoformans by alveolar macrophages Exogenous sphingosine-1-phosphate boosts acclimatization in rats exposed to acute hypobaric hypoxia: assessment of haematological and metabolic effects.High density lipoprotein stimulated migration of macrophages depends on the scavenger receptor class B, type I, PDZK1 and Akt1 and is blocked by sphingosine 1 phosphate receptor antagonists.Crosstalk of reactive oxygen species and NF-κB signaling Regulation of mammalian physiology, development, and disease by the sphingosine 1-phosphate and lysophosphatidic acid receptors.Thromboxane receptor signaling is required for fibronectin-induced matrix metalloproteinase 9 production by human and murine macrophages and is attenuated by the Arhgef1 molecule.Small molecule delivery through nanofibrous scaffolds for musculoskeletal regenerative engineering The outs and the ins of sphingosine-1-phosphate in immunity Myeloid cells as target of fingolimod action in multiple sclerosis.Mer receptor tyrosine kinase mediates both tethering and phagocytosis of apoptotic cells.Shaping the landscape: metabolic regulation of S1P gradients.Apolipoprotein E induces antiinflammatory phenotype in macrophages HDL-bound sphingosine 1-phosphate acts as a biased agonist for the endothelial cell receptor S1P1 to limit vascular inflammation.The alliance of sphingosine-1-phosphate and its receptors in immunity.Modulation of Macrophage Inflammatory Nuclear Factor κB (NF-κB) Signaling by Intracellular Cryptococcus neoformans Why targeting HDL should work as a therapeutic tool, but has not.High density lipoprotein biogenesis, cholesterol efflux, and immune cell function.Therapeutic dosing of fingolimod (FTY720) prevents cell infiltration, rapidly suppresses ocular inflammation, and maintains the blood-ocular barrier.Age-related alterations in innate immune receptor expression and ability of macrophages to respond to pathogen challenge in vitro.Fingolimod and related compounds in a spontaneous autoimmune polyneuropathy.Lyase to live by: sphingosine phosphate lyase as a therapeutic target.

P2860

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P2860

Sphingosine-1-phosphate induces an antiinflammatory phenotype in macrophages.

http://www.wikidata.org/entity/Q30436091

description

2008 nî lūn-bûn

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2008 թուականի Մարտին հրատարակուած գիտական յօդուած

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2008 թվականի մարտին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Sphingosine-1-phosphate induces an antiinflammatory phenotype in macrophages.

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Sphingosine-1-phosphate induces an antiinflammatory phenotype in macrophages.

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type

label

Sphingosine-1-phosphate induces an antiinflammatory phenotype in macrophages.

@ast

Sphingosine-1-phosphate induces an antiinflammatory phenotype in macrophages.

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prefLabel

Sphingosine-1-phosphate induces an antiinflammatory phenotype in macrophages.

@ast

Sphingosine-1-phosphate induces an antiinflammatory phenotype in macrophages.

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CIRCRESAHA.107.170779

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Circulation Research

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Sphingosine-1-phosphate induces an antiinflammatory phenotype in macrophages.

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Catherine C Hedrick

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Jeniter E Hughes

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Kevin R Lynch

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Pawel Ferdek

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Suseela Srinivasan

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P2860

Atherosclerosis — An Inflammatory Disease

Alternative activation of macrophages

Sphingosine-1-phosphate prevents tumor necrosis factor-{alpha}-mediated monocyte adhesion to aortic endothelium in mice

Sphingosine-1 phosphate prevents monocyte/endothelial interactions in type 1 diabetic NOD mice through activation of the S1P1 receptor

The many faces of macrophage activation

Sphingosine-1-phosphate: an enigmatic signalling lipid

Synthesis and biological evaluation of gamma-aminophosphonates as potent, subtype-selective sphingosine 1-phosphate receptor agonists and antagonists.

Cutting edge: Stat6-dependent substrate depletion regulates nitric oxide production.

Dissection of experimental asthma with DNA microarray analysis identifies arginase in asthma pathogenesis.

Sphingosine 1-phosphate receptors in health and disease: mechanistic insights from gene deletion studies and reverse pharmacology.

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950-958

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10.1161/CIRCRESAHA.107.170779

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8

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102

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Richard L. Proia

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18323526

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2875063

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