Vinculin controls focal adhesion formation by direct interactions with talin and actin. - sprookjes - yvandenbroek - TriplyDB

Vinculin controls focal adhesion formation by direct interactions with talin and actin.

Vinculin controls focal adhesion formation by direct interactions with talin and actin.

http://www.wikidata.org/entity/Q30441610

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Talin contains a C-terminal calpain2 cleavage site important in focal adhesion dynamics NEDD9 stabilizes focal adhesions, increases binding to the extra-cellular matrix and differentially effects 2D versus 3D cell migration Vinculin regulates cell-surface E-cadherin expression by binding to beta-catenin Integrins β1 and β3 exhibit distinct dynamic nanoscale organizations inside focal adhesions Characterization of G2L3 (GAS2-like 3), a new microtubule- and actin-binding protein related to spectraplakins Dissecting cell adhesion architecture using advanced imaging techniques Paxillin comes of age Dynamic interplay between adhesion surfaces in carcinomas: Cell-cell and cell-matrix crosstalk Mechanosensitive components of integrin adhesions: Role of vinculin Mechanosensitivity and compositional dynamics of cell-matrix adhesions Vinculin and metavinculin: oligomerization and interactions with F-actin Mechanobiology of myofibroblast adhesion in fibrotic cardiac disease αV-integrins are required for mechanotransduction in MDCK epithelial cells Local 3D matrix microenvironment regulates cell migration through spatiotemporal dynamics of contractility-dependent adhesions.The vinculin-DeltaIn20/21 mouse: characteristics of a constitutive, actin-binding deficient splice variant of vinculin CADM1 controls actin cytoskeleton assembly and regulates extracellular matrix adhesion in human mast cells Vinculin phosphorylation at residues Y100 and Y1065 is required for cellular force transmission.Vinculin controls talin engagement with the actomyosin machinery.Central Region of Talin Has a Unique Fold That Binds Vinculin and Actin ZF21 Protein, a Regulator of the Disassembly of Focal Adhesions and Cancer Metastasis, Contains a Novel Noncanonical Pleckstrin Homology Domain RIAM and Vinculin Binding to Talin Are Mutually Exclusive and Regulate Adhesion Assembly and Turnover Non-muscle myosin II takes centre stage in cell adhesion and migration Extracellular rigidity sensing by talin isoform-specific mechanical linkages Paxillin and Hic-5 interaction with vinculin is differentially regulated by Rac1 and RhoA Improved in vitro angiogenic behavior on anodized titanium dioxide nanotubes Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics.Cell adhesion: integrating cytoskeletal dynamics and cellular tension.Vinculin-p130Cas interaction is critical for focal adhesion dynamics and mechano-transduction.Integrin-associated complexes form hierarchically with variable stoichiometry in nascent adhesions A plastic relationship between vinculin-mediated tension and adhesion complex area defines adhesion size and lifetime.Identification of an actin binding surface on vinculin that mediates mechanical cell and focal adhesion properties.Low-intensity pulsed ultrasound promotes chondrogenic progenitor cell migration via focal adhesion kinase pathway.Vinculin-actin interaction couples actin retrograde flow to focal adhesions, but is dispensable for focal adhesion growth.Bidirectional remodeling of β1-integrin adhesions during chemotropic regulation of nerve growth.Investigating complexity of protein-protein interactions in focal adhesions.Kindlin-1 Is required for RhoGTPase-mediated lamellipodia formation in keratinocytes Force-induced cell polarisation is linked to RhoA-driven microtubule-independent focal-adhesion sliding Keratin 8/18 modulation of protein kinase C-mediated integrin-dependent adhesion and migration of liver epithelial cells Vinculin is a dually regulated actin filament barbed end-capping and side-binding protein Activation of vinculin induced by cholinergic stimulation regulates contraction of tracheal smooth muscle tissue.

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P2860

Vinculin controls focal adhesion formation by direct interactions with talin and actin.

http://www.wikidata.org/entity/Q30441610

description

2007 nî lūn-bûn

@nan

2007 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

Vinculin controls focal adhesion formation by direct interactions with talin and actin.

@ast

Vinculin controls focal adhesion formation by direct interactions with talin and actin.

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type

label

Vinculin controls focal adhesion formation by direct interactions with talin and actin.

@ast

Vinculin controls focal adhesion formation by direct interactions with talin and actin.

@en

prefLabel

Vinculin controls focal adhesion formation by direct interactions with talin and actin.

@ast

Vinculin controls focal adhesion formation by direct interactions with talin and actin.

@en

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Journal of Cell Biology

P1476

Vinculin controls focal adhesion formation by direct interactions with talin and actin

@en

P2093

Benny Geiger

http://www.w3.org/2001/XMLSchema#string

Charles Streuli

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Jonathan D Humphries

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Martin J Humphries

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Pengbo Wang

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P2860

Structural basis of integrin activation by talin

Molecular mapping of tyrosine-phosphorylated proteins in focal adhesions using fluorescence resonance energy transfer

Molecular cloning of human paxillin, a focal adhesion protein phosphorylated by P210BCR/ABL

Focal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains.

Paxillin: a new vinculin-binding protein present in focal adhesions

Crystal structure of the vinculin tail suggests a pathway for activation

Paxillin and focal adhesion signalling

Transmembrane crosstalk between the extracellular matrix--cytoskeleton crosstalk

Characterisation of the paxillin-binding site and the C-terminal focal adhesion targeting sequence in vinculin

Focal adhesions, contractility, and signaling

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1043-1057

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scholarly article

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10.1083/JCB.200703036

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5

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179

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Christoph Ballestrem

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2007-12-01T00:00:00Z

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5792585

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18056416

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2099183

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