High-resolution mapping of replication fork movement through the amplified dihydrofolate reductase domain in CHO cells by in-gel renaturation analysis.
about
The HeLa Pur factor binds single-stranded DNA at a specific element conserved in gene flanking regions and origins of DNA replicationRIP60, a mammalian origin-binding protein, enhances DNA bending near the dihydrofolate reductase origin of replicationPurification of RIP60 and RIP100, mammalian proteins with origin-specific DNA-binding and ATP-dependent DNA helicase activitiesPeaks cloaked in the mist: the landscape of mammalian replication originsA potential role for mini-chromosome maintenance (MCM) proteins in initiation at the dihydrofolate reductase replication origin.Initiation sites are distributed at frequent intervals in the Chinese hamster dihydrofolate reductase origin of replication but are used with very different efficienciesThe dihydrofolate reductase origin of replication does not contain any nonredundant genetic elements required for origin activity.The matrix attachment region in the Chinese hamster dihydrofolate reductase origin of replication may be required for local chromatid separation.Initiation of replication in the Chinese hamster dihydrofolate reductase domain.Mammalian origins of replication.The plant amino acid mimosine may inhibit initiation at origins of replication in Chinese hamster cells.The promoter of the Chinese hamster ovary dihydrofolate reductase gene regulates the activity of the local origin and helps define its boundariesInitiation of DNA replication in the dihydrofolate reductase locus is confined to the early S period in CHO cells synchronized with the plant amino acid mimosine.A winding road to origin discoverySpecific signals at the 3' end of the DHFR gene define one boundary of the downstream origin of replication.Activation of a mammalian origin of replication by chromosomal rearrangement.Ubiquitylation, phosphorylation and Orc2 modulate the subcellular location of Orc1 and prevent it from inducing apoptosisA revisionist replicon model for higher eukaryotic genomes.Replication initiation sites are distributed widely in the amplified CHO dihydrofolate reductase domain.Radiation effects on DNA synthesis in a defined chromosomal replicon.Mapping of replication initiation sites in mammalian genomes by two-dimensional gel analysis: stabilization and enrichment of replication intermediates by isolation on the nuclear matrix.Multiple origins of replication in the dihydrofolate reductase amplicons of a methotrexate-resistant chinese hamster cell line.Identification and characterization of a gene that is coamplified with dihydrofolate reductase in a methotrexate-resistant CHO cell lineMimosine, a novel inhibitor of DNA replication, binds to a 50 kDa protein in Chinese hamster cellsCharacterizing replication intermediates in the amplified CHO dihydrofolate reductase domain by two novel gel electrophoretic techniques.Composite patterns in neutral/neutral two-dimensional gels demonstrate inefficient replication origin usage.The Chinese hamster dihydrofolate reductase origin consists of multiple potential nascent-strand start sitesLagging-strand, early-labelling, and two-dimensional gel assays suggest multiple potential initiation sites in the Chinese hamster dihydrofolate reductase originAttachment to the nuclear matrix mediates specific alterations in chromatin structure.Sequence and context effects on origin function in mammalian cells.A new class of reversible cell cycle inhibitors.Identification of primary initiation sites for DNA replication in the hamster dihydrofolate reductase gene initiation zone.Nuclear scaffold attachment stimulates, but is not essential for ARS activity in Saccharomyces cerevisiae: analysis of the Drosophila ftz SARDynamics of association of origins of DNA replication with the nuclear matrix during the cell cycleModular sequence elements associated with origin regions in eukaryotic chromosomal DNA.Pre-replication complex proteins assemble at regions of low nucleosome occupancy within the Chinese hamster dihydrofolate reductase initiation zoneAmbiguities in results obtained with 2D gel replicon mapping techniquesAnalysis of the autonomous replication behavior in human cells of the dihydrofolate reductase putative chromosomal origin of replication.Emetine allows identification of origins of mammalian DNA replication by imbalanced DNA synthesis, not through conservative nucleosome segregationDNA loops: structural and functional properties of scaffold-attached regions.
P2860
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P2860
High-resolution mapping of replication fork movement through the amplified dihydrofolate reductase domain in CHO cells by in-gel renaturation analysis.
description
1989 nî lūn-bûn
@nan
1989 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
High-resolution mapping of rep ...... in-gel renaturation analysis.
@ast
High-resolution mapping of rep ...... in-gel renaturation analysis.
@en
type
label
High-resolution mapping of rep ...... in-gel renaturation analysis.
@ast
High-resolution mapping of rep ...... in-gel renaturation analysis.
@en
prefLabel
High-resolution mapping of rep ...... in-gel renaturation analysis.
@ast
High-resolution mapping of rep ...... in-gel renaturation analysis.
@en
P2860
P356
P1476
High-resolution mapping of rep ...... in-gel renaturation analysis.
@en
P2093
P2860
P304
P356
10.1128/MCB.9.2.523
P407
P577
1989-02-01T00:00:00Z