Immunization with cDNA expressed by amastigotes of Trypanosoma cruzi elicits protective immune response against experimental infection
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Testing of four Leishmania vaccine candidates in a mouse model of infection with Leishmania (Viannia) braziliensis, the main causative agent of cutaneous leishmaniasis in the New World.Silencing cytokeratin 18 gene inhibits intracellular replication of Trypanosoma cruzi in HeLa cells but not binding and invasion of trypanosomesGenetic immunization converts the trypanosoma cruzi B-Cell mitogen proline racemase to an effective immunogen.Genetic vaccination against experimental infection with myotropic parasite strains of Trypanosoma cruzi.CD8(+) T cell-mediated immunity during Trypanosoma cruzi infection: a path for vaccine development?CD8+-T-cell-dependent control of Trypanosoma cruzi infection in a highly susceptible mouse strain after immunization with recombinant proteins based on amastigote surface protein 2.Recombinant yellow fever viruses elicit CD8+ T cell responses and protective immunity against Trypanosoma cruziVaccination using recombinants influenza and adenoviruses encoding amastigote surface protein-2 are highly effective on protection against Trypanosoma cruzi infectionBiological and immunological characterization of recombinant Yellow Fever 17D viruses expressing a Trypanosoma cruzi Amastigote Surface Protein-2 CD8+ T cell epitope at two distinct regions of the genomeHeterologous plasmid DNA prime-recombinant human adenovirus 5 boost vaccination generates a stable pool of protective long-lived CD8(+) T effector memory cells specific for a human parasite, Trypanosoma cruziA human type 5 adenovirus-based Trypanosoma cruzi therapeutic vaccine re-programs immune response and reverses chronic cardiomyopathy.Antigen targeting to dendritic cells allows the identification of a CD4 T-cell epitope within an immunodominant Trypanosoma cruzi antigenA DNA vaccine encoding for TcSSP4 induces protection against acute and chronic infection in experimental Chagas diseaseGeneration, specificity, and function of CD8+ T cells in Trypanosoma cruzi infection.Current status and future prospects for a vaccine against American trypanosomiasis.Novel protective antigens expressed by Trypanosoma cruzi amastigotes provide immunity to mice highly susceptible to Chagas' disease.DNA Vaccines against Protozoan Parasites: Advances and ChallengesChagas' disease: an update on immune mechanisms and therapeutic strategiesPerforin and gamma interferon expression are required for CD4+ and CD8+ T-cell-dependent protective immunity against a human parasite, Trypanosoma cruzi, elicited by heterologous plasmid DNA prime-recombinant adenovirus 5 boost vaccination.Vaccination approaches against Trypanosoma cruzi infection.Invasion-inhibitory antibodies elicited by immunization with Plasmodium vivax apical membrane antigen-1 expressed in Pichia pastoris yeast.Adenovirus vector-induced CD8⁺ T effector memory cell differentiation and recirculation, but not proliferation, are important for protective immunity against experimental Trypanosoma cruzi InfectionProphylactic and therapeutic DNA vaccines against Chagas disease.Characterization and Diagnostic Application of Trypanosoma cruzi Trypomastigote Excreted-Secreted Antigens Shed in Extracellular Vesicles Released from Infected Mammalian Cells.Distinct kinetics of effector CD8+ cytotoxic T cells after infection with Trypanosoma cruzi in naive or vaccinated mice.Engineered trivalent immunogen adjuvanted with a STING agonist confers protection against Trypanosoma cruzi infection.Evaluation of immune responses raised against Tc13 antigens of Trypanosoma cruzi in the outcome of murine experimental infection.Immunological and pathological responses in BALB/c mice induced by genetic administration of Tc 13 Tul antigen of Trypanosoma cruzi.
P2860
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P2860
Immunization with cDNA expressed by amastigotes of Trypanosoma cruzi elicits protective immune response against experimental infection
description
2003 nî lūn-bûn
@nan
2003 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Immunization with cDNA express ...... against experimental infection
@ast
Immunization with cDNA express ...... against experimental infection
@en
type
label
Immunization with cDNA express ...... against experimental infection
@ast
Immunization with cDNA express ...... against experimental infection
@en
prefLabel
Immunization with cDNA express ...... against experimental infection
@ast
Immunization with cDNA express ...... against experimental infection
@en
P2093
P2860
P1476
Immunization with cDNA express ...... against experimental infection
@en
P2093
Adriana E Fujimura
Mauricio M Rodrigues
Sheila S Kinoshita
P2860
P304
P356
10.1128/IAI.71.5.2744-2757.2003
P407
P577
2003-05-01T00:00:00Z