Cortactin has an essential and specific role in osteoclast actin assembly - sprookjes - yvandenbroek - TriplyDB

Cortactin has an essential and specific role in osteoclast actin assembly

Cortactin has an essential and specific role in osteoclast actin assembly

http://www.wikidata.org/entity/Q30477461

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Hematopoietic lineage cell-specific protein 1 functions in concert with the Wiskott-Aldrich syndrome protein to promote podosome array organization and chemotaxis in dendritic cells Tks5-dependent formation of circumferential podosomes/invadopodia mediates cell-cell fusion Cortactin branches out: roles in regulating protrusive actin dynamics Regulation of osteoclasts by membrane-derived lipid mediators Regulation of osteoclast structure and function by FAK family kinases HDAC6 modulates cell motility by altering the acetylation level of cortactin.Paxillin phosphorylation controls invadopodia/podosomes spatiotemporal organization.Cortactin promotes migration and platelet-derived growth factor-induced actin reorganization by signaling to Rho-GTPases.Lysosomal cathepsin B participates in the podosome-mediated extracellular matrix degradation and invasion via secreted lysosomes in v-Src fibroblasts.Podosomes are present in a postsynaptic apparatus and participate in its maturation.Involvement of actin polymerization in podosome dynamics.CD2AP links cortactin and capping protein at the cell periphery to facilitate formation of lamellipodia.Microtubule dynamic instability controls podosome patterning in osteoclasts through EB1, cortactin, and Src.Interactions with actin monomers, actin filaments, and Arp2/3 complex define the roles of WASP family proteins and cortactin in coordinately regulating branched actin networks Cell invasion by Neisseria meningitidis requires a functional interplay between the focal adhesion kinase, Src and cortactin.Cellular processes of v-Src transformation revealed by gene profiling of primary cells--implications for human cancer.Time-lapse reveals that osteoclasts can move across the bone surface while resorbing.Osteoclast motility: putting the brakes on bone resorption.Cytokine-induced tumor suppressors: a GRIM story Regulation of sealing ring formation by L-plastin and cortactin in osteoclasts.Astrocyte processes label for filamentous actin and reorient early within the optic nerve head in a rat glaucoma model.Cortactin: a multifunctional regulator of cellular invasiveness Cortactin colocalizes with filopodial actin and accumulates at IgCAM adhesion sites in Aplysia growth cones.Src phosphorylation of cortactin enhances actin assembly.CD44 and beta3 integrin organize two functionally distinct actin-based domains in osteoclasts Astrocyte Structural and Molecular Response to Elevated Intraocular Pressure Occurs Rapidly and Precedes Axonal Tubulin Rearrangement within the Optic Nerve Head in a Rat Model.The tyrosine kinase activity of c-Src regulates actin dynamics and organization of podosomes in osteoclasts Molecular analysis of Arp2/3 complex activation in cells.Regulation of the actin cytoskeleton in cancer cell migration and invasion.Calcium signalling and calcium transport in bone disease.A new role for cortactin in invadopodia: regulation of protease secretion.Adhesions ring: a structural comparison between podosomes and the immune synapse.Cortactin in tumor invasiveness.GRIM-19 inhibits v-Src-induced cell motility by interfering with cytoskeletal restructuring.Silencing of atp6v1c1 prevents breast cancer growth and bone metastasis.Cortactin is a functional target of E-cadherin-activated Src family kinases in MCF7 epithelial monolayers c-Cbl and Cbl-b act redundantly to protect osteoclasts from apoptosis and to displace HDAC6 from beta-tubulin, stabilizing microtubules and podosomes Signaling networks regulating leukocyte podosome dynamics and function.New approaches to targeting the actin cytoskeleton for chemotherapy.Repositioning Potential of PAK4 to Osteoclastic Bone Resorption.

P2860

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P2860

Cortactin has an essential and specific role in osteoclast actin assembly

http://www.wikidata.org/entity/Q30477461

description

2006 nî lūn-bûn

@nan

2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի ապրիլին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

Cortactin has an essential and specific role in osteoclast actin assembly

@ast

Cortactin has an essential and specific role in osteoclast actin assembly

@en

type

label

Cortactin has an essential and specific role in osteoclast actin assembly

@ast

Cortactin has an essential and specific role in osteoclast actin assembly

@en

prefLabel

Cortactin has an essential and specific role in osteoclast actin assembly

@ast

Cortactin has an essential and specific role in osteoclast actin assembly

@en

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MBC.E06-03-0187

P1433

Molecular Biology of the Cell

P1476

Cortactin has an essential and specific role in osteoclast actin assembly

@en

P2093

F Patrick Ross

http://www.w3.org/2001/XMLSchema#string

Indra Chandrasekar

http://www.w3.org/2001/XMLSchema#string

Roberta Faccio

http://www.w3.org/2001/XMLSchema#string

P2860

Cortactin interacts with WIP in regulating Arp2/3 activation and membrane protrusion

The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly

Podosomes display actin turnover and dynamic self-organization in osteoclasts expressing actin-green fluorescent protein.

Monoclonal antibodies to individual tyrosine-phosphorylated protein substrates of oncogene-encoded tyrosine kinases.

Wiskott-Aldrich syndrome protein regulates podosomes in primary human macrophages

Cortactin and dynamin are required for the clathrin-independent endocytosis of gammac cytokine receptor.

Cortactin localization to sites of actin assembly in lamellipodia requires interactions with F-actin and the Arp2/3 complex.

Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL

A Cortactin-CD2-associated protein (CD2AP) complex provides a novel link between epidermal growth factor receptor endocytosis and the actin cytoskeleton

Cortactin: coupling membrane dynamics to cortical actin assembly

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2882-2895

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scholarly article

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10.1091/MBC.E06-03-0187

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7

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P478

17

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Shandiz Tehrani

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2006-04-12T00:00:00Z

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7167933

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16611741

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1483026

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