Multiple-motor based transport and its regulation by Tau. - sprookjes - yvandenbroek - TriplyDB

Multiple-motor based transport and its regulation by Tau.

Multiple-motor based transport and its regulation by Tau.

http://www.wikidata.org/entity/Q30478710

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Basic mechanisms for recognition and transport of synaptic cargos Stepping, strain gating, and an unexpected force-velocity curve for multiple-motor-based transport Collective dynamics of processive cytoskeletal motors The axonal cytoskeleton: from organization to function Axonal transport: cargo-specific mechanisms of motility and regulation Brain-penetrant microtubule-stabilizing compounds as potential therapeutic agents for tauopathies Microtubule-stabilizing agents as potential therapeutics for neurodegenerative disease Developing therapeutic approaches to tau, selected kinases, and related neuronal protein targets The axonal transport of mitochondria Tau and tauopathies Load-induced enhancement of Dynein force production by LIS1-NudE in vivo and in vitro Activation of conventional kinesin motors in clusters by Shaw voltage-gated K+ channels.Differential regulation of dynein and kinesin motor proteins by tau An improved optical tweezers assay for measuring the force generation of single kinesin molecules.A cytoplasmic dynein tail mutation impairs motor processivity.A comparison of step-detection methods: how well can you do?Transport of beads by several kinesin motors Kinesin and dynein-dynactin at intersecting microtubules: motor density affects dynein function Myosin V and Kinesin act as tethers to enhance each others' processivity.Coordination of Kinesin motors pulling on fluid membranes.Force-velocity curves of motor proteins cooperating in vivo.The amino terminus of tau inhibits kinesin-dependent axonal transport: implications for filament toxicity.On the use of in vivo cargo velocity as a biophysical marker Motor number controls cargo switching at actin-microtubule intersections in vitro Tuning microtubule-based transport through filamentous MAPs: the problem of dynein.β-Amyloid impairs axonal BDNF retrograde trafficking.Transient binding of dynein controls bidirectional long-range motility of early endosomes Phosphorylation in the amino terminus of tau prevents inhibition of anterograde axonal transport.Molecular crowding creates traffic jams of kinesin motors on microtubules Ndel1-derived peptides modulate bidirectional transport of injected beads in the squid giant axon.Motor transport of self-assembled cargos in crowded environments.Measuring collective transport by defined numbers of processive and nonprocessive kinesin motors Correlative live-cell and superresolution microscopy reveals cargo transport dynamics at microtubule intersections.Quantitative optical trapping on single organelles in cell extract.Probing dynein and kinesin stepping with mechanical manipulation in a living cell.Globally visualizing the microtubule-dependent transport behaviors of influenza virus in live cells.Motor coupling through lipid membranes enhances transport velocities for ensembles of myosin Va A method for multiprotein assembly in cells reveals independent action of kinesins in complex Cooperative protofilament switching emerges from inter-motor interference in multiple-motor transport.Autoregulatory mechanism for dynactin control of processive and diffusive dynein transport.

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P2860

Multiple-motor based transport and its regulation by Tau.

http://www.wikidata.org/entity/Q30478710

description

2006 nî lūn-bûn

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2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

Multiple-motor based transport and its regulation by Tau.

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Multiple-motor based transport and its regulation by Tau.

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Multiple-motor based transport and its regulation by Tau.

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Multiple-motor based transport and its regulation by Tau.

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Multiple-motor based transport and its regulation by Tau.

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PNAS.0607919104

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Proceedings of the National Academy of Sciences of the United States of America

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Multiple-motor based transport and its regulation by Tau.

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P2093

Brian C Carter

http://www.w3.org/2001/XMLSchema#string

David S Razafsky

http://www.w3.org/2001/XMLSchema#string

Michael Vershinin

http://www.w3.org/2001/XMLSchema#string

Stephen J King

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Steven P Gross

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P2860

Tau is enriched on dynamic microtubules in the distal region of growing axons

Cooperative cargo transport by several molecular motors.

Two activators of microtubule-based vesicle transport

Tau binds to the distal axon early in development of polarity in a microtubule- and microfilament-dependent manner

The distribution of tau in the mammalian central nervous system

Bead movement by single kinesin molecules studied with optical tweezers.

Force generation of organelle transport measured in vivo by an infrared laser trap.

Organelle transport along microtubules in Xenopus melanophores: evidence for cooperation between multiple motors.

Probing the kinesin reaction cycle with a 2D optical force clamp

Differential regulation of microtubule dynamics by three- and four-repeat tau: implications for the onset of neurodegenerative disease

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87-92

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