Mal3, the Schizosaccharomyces pombe homolog of EB1, changes the microtubule lattice
about
Interaction of CDK5RAP2 with EB1 to track growing microtubule tips and to regulate microtubule dynamicsAhead of the Curve: New Insights into Microtubule Dynamics+TIPs: SxIPping along microtubule endsS. pombe kinesins-8 promote both nucleation and catastrophe of microtubulesPhosphorylation of EB2 by Aurora B and CDK1 ensures mitotic progression and genome stability.Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB ProteinsElectron tomography reveals novel microtubule lattice and microtubule organizing centre defects in +TIP mutantsEB1 recognizes the nucleotide state of tubulin in the microtubule latticePenrose-Hameroff orchestrated objective-reduction proposal for human consciousness is not biologically feasibleMammalian end binding proteins control persistent microtubule growthThe Ndc80 kinetochore complex forms oligomeric arrays along microtubulesTemplate-free 13-protofilament microtubule–MAP assembly visualized at 8 Å resolutionConformational changes in tubulin in GMPCPP and GDP-taxol microtubules observed by cryoelectron microscopy.A TOG: -tubulin Complex Structure Reveals Conformation-Based Mechanisms for a Microtubule PolymeraseEBs Recognize a Nucleotide-Dependent Structural Cap at Growing Microtubule EndsRegulation of microtubule dynamics by Bim1 and Bik1, the budding yeast members of the EB1 and CLIP-170 families of plus-end tracking proteins.Synergy between XMAP215 and EB1 increases microtubule growth rates to physiological levelsMal3 masks catastrophe events in Schizosaccharomyces pombe microtubules by inhibiting shrinkage and promoting rescue.Lattice structure of cytoplasmic microtubules in a cultured Mammalian cell.Electron tomography reveals a flared morphology on growing microtubule ends.The mechanisms of microtubule catastrophe and rescue: implications from analysis of a dimer-scale computational model.Ectopic A-lattice seams destabilize microtubules.GDP-to-GTP exchange on the microtubule end can contribute to the frequency of catastrophe.The contribution of αβ-tubulin curvature to microtubule dynamics.GTPgammaS microtubules mimic the growing microtubule end structure recognized by end-binding proteins (EBs).Insights into EB1 structure and the role of its C-terminal domain for discriminating microtubule tips from the lattice.Encoding the microtubule structure: Allosteric interactions between the microtubule +TIP complex master regulators and TOG-domain proteins.Phosphoregulation of the budding yeast EB1 homologue Bim1p by Aurora/Ipl1p.Interactions between EB1 and microtubules: dramatic effect of affinity tags and evidence for cooperative behavior.Shaping microtubules into diverse patterns: molecular connections for setting up both ends.EB1 promotes microtubule dynamics by recruiting Sentin in Drosophila cells.An unconventional interaction between Dis1/TOG and Mal3/EB1 in fission yeast promotes the fidelity of chromosome segregation.Manipulation and quantification of microtubule lattice integrity.Structural differences between yeast and mammalian microtubules revealed by cryo-EM.Analysis of the strength of interfacial hydrogen bonds between tubulin dimers using quantum theory of atoms in moleculesMechanical effects of EB1 on microtubules depend on GTP hydrolysis state and presence of paclitaxel.Nucleotide- and Mal3-dependent changes in fission yeast microtubules suggest a structural plasticity view of dynamics.Structural and functional differences between porcine brain and budding yeast microtubules.GTP-binding facilitates EB1 recruitment onto microtubules by relieving its auto-inhibition.Opposing kinesin complexes queue at plus tips to ensure microtubule catastrophe at cell ends
P2860
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P2860
Mal3, the Schizosaccharomyces pombe homolog of EB1, changes the microtubule lattice
description
2008 nî lūn-bûn
@nan
2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Mal3, the Schizosaccharomyces pombe homolog of EB1, changes the microtubule lattice
@ast
Mal3, the Schizosaccharomyces pombe homolog of EB1, changes the microtubule lattice
@en
type
label
Mal3, the Schizosaccharomyces pombe homolog of EB1, changes the microtubule lattice
@ast
Mal3, the Schizosaccharomyces pombe homolog of EB1, changes the microtubule lattice
@en
prefLabel
Mal3, the Schizosaccharomyces pombe homolog of EB1, changes the microtubule lattice
@ast
Mal3, the Schizosaccharomyces pombe homolog of EB1, changes the microtubule lattice
@en
P2860
P50
P356
P1476
Mal3, the Schizosaccharomyces pombe homolog of EB1, changes the microtubule lattice
@en
P2093
Michael Osei
Miho Katsuki
P2860
P2888
P304
P356
10.1038/NSMB.1482
P577
2008-09-14T00:00:00Z