Orexin (hypocretin) gene transfer diminishes narcoleptic sleep behavior in mice. - sprookjes - yvandenbroek - TriplyDB

Orexin (hypocretin) gene transfer diminishes narcoleptic sleep behavior in mice.

Orexin (hypocretin) gene transfer diminishes narcoleptic sleep behavior in mice.

http://www.wikidata.org/entity/Q30485386

about

Control of sleep and wakefulness Unmet needs of patients with narcolepsy: perspectives on emerging treatment options Narcolepsy: neural mechanisms of sleepiness and cataplexy Neurons containing orexin or melanin concentrating hormone reciprocally regulate wake and sleep Viral strategies for studying the brain, including a replication-restricted self-amplifying delta-G vesicular stomatis virus that rapidly expresses transgenes in brain and can generate a multicolor golgi-like expression Narcolepsy and orexins: an example of progress in sleep research.Hypocretin-2 saporin lesions of the ventrolateral periaquaductal gray (vlPAG) increase REM sleep in hypocretin knockout mice.An adeno-associated viral vector transduces the rat hypothalamus and amygdala more efficient than a lentiviral vector The evolving story of orexin biology: the hits keep coming Suvorexant for the treatment of insomnia.To ingest or rest? Specialized roles of lateral hypothalamic area neurons in coordinating energy balance.Effects of hypocretin/orexin cell transplantation on narcoleptic-like sleep behavior in rats.Effects of orexin gene transfer in the dorsolateral pons in orexin knockout mice Orexin gene transfer into the amygdala suppresses both spontaneous and emotion-induced cataplexy in orexin-knockout mice.Animal models of narcolepsy.Role of orexin in modulating arousal, feeding, and motivation.Orexin gene transfer into zona incerta neurons suppresses muscle paralysis in narcoleptic mice Neuroanatomy of melanocortin-4 receptor pathway in the lateral hypothalamic area Orexin gene therapy restores the timing and maintenance of wakefulness in narcoleptic mice.Activity of pontine neurons during sleep and cataplexy in hypocretin knock-out mice New developments in the management of narcolepsy.Emerging treatments for narcolepsy and its related disorders.Challenges in the development of therapeutics for narcolepsy.Rewiring brain circuits to block cataplexy in murine models of narcolepsy.New Neuroscience Tools That Are Identifying the Sleep-Wake Circuit.Recent advances in the treatment of narcolepsy.Cholinergic control of morphine-induced locomotion in rostromedial tegmental nucleus versus ventral tegmental area sites.Orexin Receptor Antagonists

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P2860

Orexin (hypocretin) gene transfer diminishes narcoleptic sleep behavior in mice.

http://www.wikidata.org/entity/Q30485386

description

2008 nî lūn-bûn

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2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2008 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Orexin (hypocretin) gene transfer diminishes narcoleptic sleep behavior in mice.

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Orexin (hypocretin) gene transfer diminishes narcoleptic sleep behavior in mice.

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type

label

Orexin (hypocretin) gene transfer diminishes narcoleptic sleep behavior in mice.

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Orexin (hypocretin) gene transfer diminishes narcoleptic sleep behavior in mice.

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prefLabel

Orexin (hypocretin) gene transfer diminishes narcoleptic sleep behavior in mice.

@ast

Orexin (hypocretin) gene transfer diminishes narcoleptic sleep behavior in mice.

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J.1460-9568.2008.06446.X

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European Journal of Neuroscience

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Orexin (hypocretin) gene transfer diminishes narcoleptic sleep behavior in mice.

@en

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Carlos Blanco-Centurion

http://www.w3.org/2001/XMLSchema#string

Masashi Yanagisawa

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Meng Liu

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Priyattam J Shiromani

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Rachael Neve

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Satvinder Kaur

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Stephen Thankachan

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Suraiya Begum

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Takeshi Sakurai

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P2860

A role of melanin-concentrating hormone producing neurons in the central regulation of paradoxical sleep

Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior

The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity

Transplantation of hypocretin neurons into the pontine reticular formation: preliminary results

The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene

A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains

Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation

Neurons containing hypocretin (orexin) project to multiple neuronal systems

Orexin peptides prevent cataplexy and improve wakefulness in an orexin neuron-ablated model of narcolepsy in mice.

Reduced number of hypocretin neurons in human narcolepsy.

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