about
Evolution of pathogenicity and sexual reproduction in eight Candida genomesPEDRo: a database for storing, searching and disseminating experimental proteomics dataCandida albicans genome sequence: a platform for genomics in the absence of geneticsPosttranslational modifications of proteins in the pathobiology of medically relevant fungiFungal iron availability during deep seated candidiasis is defined by a complex interplay involving systemic and local eventsA transcriptome analysis of isoamyl alcohol-induced filamentation in yeast reveals a novel role for Gre2p as isovaleraldehyde reductase.Oma1 Links Mitochondrial Protein Quality Control and TOR Signaling To Modulate Physiological Plasticity and Cellular Stress Responses.Differential adaptation of Candida albicans in vivo modulates immune recognition by dectin-1From START to FINISH: the influence of osmotic stress on the cell cycleDevelopmental regulation of an adhesin gene during cellular morphogenesis in the fungal pathogen Candida albicans.Phosphorylation regulates polarisation of chitin synthesis in Candida albicansCell wall protection by the Candida albicans class I chitin synthasesA systematic approach to modeling, capturing, and disseminating proteomics experimental data.Pho4 mediates phosphate acquisition in Candida albicans and is vital for stress resistance and metal homeostasisPhylogenetic diversity of stress signalling pathways in fungi.Early-expressed chemokines predict kidney immunopathology in experimental disseminated Candida albicans infectionsElevated catalase expression in a fungal pathogen is a double-edged sword of iron.A multifunctional mannosyltransferase family in Candida albicans determines cell wall mannan structure and host-fungus interactions.Functional specialization and differential regulation of short-chain carboxylic acid transporters in the pathogen Candida albicansAnalysing GCN4 translational control in yeast by stochastic chemical kinetics modelling and simulationMechanisms underlying the exquisite sensitivity of Candida albicans to combinatorial cationic and oxidative stress that enhances the potent fungicidal activity of phagocytes.Antifungal agents: mechanisms of action.A systems biology analysis of long and short-term memories of osmotic stress adaptation in fungiSmall but crucial: the novel small heat shock protein Hsp21 mediates stress adaptation and virulence in Candida albicans.Differential regulation of kidney and spleen cytokine responses in mice challenged with pathology-standardized doses of Candida albicans mannosylation mutantsCellular responses of Candida albicans to phagocytosis and the extracellular activities of neutrophils are critical to counteract carbohydrate starvation, oxidative and nitrosative stressHsp90 orchestrates transcriptional regulation by Hsf1 and cell wall remodelling by MAPK signalling during thermal adaptation in a pathogenic yeast.Activation of the heat shock transcription factor Hsf1 is essential for the full virulence of the fungal pathogen Candida albicans.Information quality in proteomics.Immune sensing of Candida albicans requires cooperative recognition of mannans and glucans by lectin and Toll-like receptorsNiche-specific regulation of central metabolic pathways in a fungal pathogen.The Mnn2 mannosyltransferase family modulates mannoprotein fibril length, immune recognition and virulence of Candida albicansFungal morphogenesis and host invasion.Impact of the unfolded protein response upon genome-wide expression patterns, and the role of Hac1 in the polarized growth, of Candida albicans.Role of the Candida albicans MNN1 gene family in cell wall structure and virulence.Molecular and proteomic analyses highlight the importance of ubiquitination for the stress resistance, metabolic adaptation, morphogenetic regulation and virulence of Candida albicansGenome-wide analysis of Candida albicans gene expression patterns during infection of the mammalian kidney.Metabolism in fungal pathogenesis.Effects of depleting the essential central metabolic enzyme fructose-1,6-bisphosphate aldolase on the growth and viability of Candida albicans: implications for antifungal drug target discovery.Glycosylation status of the C. albicans cell wall affects the efficiency of neutrophil phagocytosis and killing but not cytokine signaling.
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Alistair Brown
@fr
Alistair J P Brown
@en
Alistair J P Brown
@es
Alistair J P Brown
@nl
Alistair J P Brown
@sl
type
label
Alistair Brown
@fr
Alistair J P Brown
@en
Alistair J P Brown
@es
Alistair J P Brown
@nl
Alistair J P Brown
@sl
altLabel
Brown AJ
@en
prefLabel
Alistair Brown
@fr
Alistair J P Brown
@en
Alistair J P Brown
@es
Alistair J P Brown
@nl
Alistair J P Brown
@sl
P108
P106
P21
P31
P496
0000-0003-1406-4251