Mycolactone impairs T cell homing by suppressing microRNA control of L-selectin expression
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Bacterial Toxins as Pathogen Weapons Against PhagocytesMicroRNA regulation of T-lymphocyte immunity: modulation of molecular networks responsible for T-cell activation, differentiation, and developmentmicroRNAs function in CD8+T cell biologyThe pathogenic mechanism of the Mycobacterium ulcerans virulence factor, mycolactone, depends on blockade of protein translocation into the ERKinetics of mycolactone in human subcutaneous tissue during antibiotic therapy for Mycobacterium ulcerans diseaseQuantification and accurate normalisation of small RNAs through new custom RT-qPCR arrays demonstrates Salmonella-induced microRNAs in human monocytesOn the origin of Mycobacterium ulcerans, the causative agent of Buruli ulcer.Structure-activity relationship studies on the macrolide exotoxin mycolactone of Mycobacterium ulcerans.Transiently reduced PI3K/Akt activity drives the development of regulatory function in antigen-stimulated Naïve T-cells.Combined inflammatory and metabolic defects reflected by reduced serum protein levels in patients with Buruli ulcer diseaseShaping mycolactone for therapeutic use against inflammatory disorders.Interferon-γ Is a Crucial Activator of Early Host Immune Defense against Mycobacterium ulcerans Infection in Mice.Antibody-Mediated Neutralization of the Exotoxin Mycolactone, the Main Virulence Factor Produced by Mycobacterium ulceransMetabolomic profiles delineate mycolactone signature in Buruli ulcer disease.Mycolactone activation of Wiskott-Aldrich syndrome proteins underpins Buruli ulcer formation.Mycolactone-mediated neurite degeneration and functional effects in cultured human and rat DRG neurons: Mechanisms underlying hypoalgesia in Buruli ulcerMycolactone subverts immunity by selectively blocking the Sec61 translocon.History, biology and chemistry of Mycobacterium ulcerans infections (Buruli ulcer disease).Pathogenesis of skin ulcers: lessons from the Mycobacterium ulcerans and Leishmania spp. pathogens.Pleiotropic molecular effects of the Mycobacterium ulcerans virulence factor mycolactone underlying the cell death and immunosuppression seen in Buruli ulcer.Recent advances: role of mycolactone in the pathogenesis and monitoring of Mycobacterium ulcerans infection/Buruli ulcer disease.Investigation of wild-type and mycolactone-negative mutant Mycobacterium ulcerans on skeletal muscle: IGF-1 protects against mycolactone-induced muscle catabolism.Infiltrating leukocytes surround early Buruli ulcer lesions, but are unable to reach the mycolactone producing mycobacteria.The chemistry and biology of mycolactones.Soluble HLA-G modulates miRNA-210 and miRNA-451 expression in activated CD4+ T lymphocytes.Mycolactone displays anti-inflammatory effects on the nervous system.Membrane perturbing properties of toxin mycolactone from Mycobacterium ulcerans.The potent effect of mycolactone on lipid membranes.Proteomics Reveals Scope of Mycolactone-mediated Sec61 Blockade and Distinctive Stress SignatureIFN-γ and IL-5 whole blood response directed against mycolactone polyketide synthase domains in patients with infection
P2860
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P2860
Mycolactone impairs T cell homing by suppressing microRNA control of L-selectin expression
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2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Mycolactone impairs T cell hom ...... ntrol of L-selectin expression
@ast
Mycolactone impairs T cell hom ...... ntrol of L-selectin expression
@en
type
label
Mycolactone impairs T cell hom ...... ntrol of L-selectin expression
@ast
Mycolactone impairs T cell hom ...... ntrol of L-selectin expression
@en
prefLabel
Mycolactone impairs T cell hom ...... ntrol of L-selectin expression
@ast
Mycolactone impairs T cell hom ...... ntrol of L-selectin expression
@en
P2093
P2860
P356
P1476
Mycolactone impairs T cell hom ...... ntrol of L-selectin expression
@en
P2093
Agnès Le Bon
Caroline Demangel
Florent Carrette
François Asperti-Boursin
Georges Bismuth
Laure Guenin-Macé
Laxmee Caleechurn
Vincenzo Di Bartolo
P2860
P304
12833-12838
P356
10.1073/PNAS.1016496108
P407
P577
2011-07-18T00:00:00Z