Two cyclin-dependent kinase pathways are essential for polarized trafficking of presynaptic components
about
Analysis of substrate specificity and cyclin Y binding of PCTAIRE-1 kinaseBrain-selective kinase 2 (BRSK2) phosphorylation on PCTAIRE1 negatively regulates glucose-stimulated insulin secretion in pancreatic β-cellsPhosphorylation of cyclin Y by CDK14 induces its ubiquitination and degradationCyclin-dependent kinase 16/PCTAIRE kinase 1 is activated by cyclin Y and is essential for spermatogenesisTargeting cyclin-dependent kinases in human cancers: from small molecules to Peptide inhibitorsGenetic analysis of a novel tubulin mutation that redirects synaptic vesicle targeting and causes neurite degeneration in C. elegansThe vesicle protein SAM-4 regulates the processivity of synaptic vesicle transportUNC-16 (JIP3) Acts Through Synapse-Assembly Proteins to Inhibit the Active Transport of Cell Soma Organelles to Caenorhabditis elegans Motor Neuron Axons.Synapse-Assembly Proteins Maintain Synaptic Vesicle Cluster Stability and Regulate Synaptic Vesicle Transport in Caenorhabditis elegans.Parkinson's disease genes VPS35 and EIF4G1 interact genetically and converge on α-synucleinX-exome sequencing of 405 unresolved families identifies seven novel intellectual disability genesCyclin-dependent kinase 5 is involved in the phosphorylation of gephyrin and clustering of GABAA receptors at inhibitory synapses of hippocampal neuronsCdk5 is required for memory function and hippocampal plasticity via the cAMP signaling pathway.Growth factors in synaptic function.Microtubule-based localization of a synaptic calcium-signaling complex is required for left-right neuronal asymmetry in C. elegans.The kinesin-3 family motor KLP-4 regulates anterograde trafficking of GLR-1 glutamate receptors in the ventral nerve cord of Caenorhabditis elegans.Autonomous screening of C. elegans identifies genes implicated in synaptogenesisPCTAIRE1 phosphorylates p27 and regulates mitosis in cancer cells.Cyclin Y inhibits plasticity-induced AMPA receptor exocytosis and LTP.Deep phenotyping unveils hidden traits and genetic relations in subtle mutants.cdc-25.4, a Caenorhabditis elegans Ortholog of cdc25, Is Required for Male Mating BehaviorLocal inhibition of microtubule dynamics by dynein is required for neuronal cargo distribution.Autoinhibition of a Neuronal Kinesin UNC-104/KIF1A Regulates the Size and Density of Synapses.Differential regulation of polarized synaptic vesicle trafficking and synapse stability in neural circuit rewiring in Caenorhabditis elegansA new treatment for cognitive disorders related to in utero exposure to alcohol.Prenatal alcohol exposure alters p35, CDK5 and GSK3β in the medial frontal cortex and hippocampus of adolescent miceAt the Fulcrum in Health and Disease: Cdk5 and the Balancing Acts of Neuronal Structure and Physiology.Increased synaptophysin is involved in inflammation-induced heat hyperalgesia mediated by cyclin-dependent kinase 5 in rats.Optical control of cell signaling by single-chain photoswitchable kinasesThe scaffolding protein SYD-2/Liprin-α regulates the mobility and polarized distribution of dense-core vesicles in C. elegans motor neurons14-3-3 Binding to Cyclin Y contributes to cyclin Y/CDK14 association.Impaired motoneuronal retrograde transport in two models of SBMA implicates two sites of androgen action.Control of sleep by cyclin A and its regulator.Cyclin-dependent kinase 5 regulates the polarized trafficking of neuropeptide-containing dense-core vesicles in Caenorhabditis elegans motor neurons.Cyclin Y phosphorylation- and 14-3-3-binding-dependent activation of PCTAIRE-1/CDK16.Structure and inhibitor specificity of the PCTAIRE-family kinase CDK16.Cyclin Y-mediated transcript profiling reveals several important functional pathways regulated by Cyclin Y in hippocampal neuronsOrphan kinases turn eccentric: a new class of cyclin Y-activated, membrane-targeted CDKsRegulation of DLK-1 kinase activity by calcium-mediated dissociation from an inhibitory isoformCdk5 regulates developmental remodeling of mushroom body neurons in Drosophila.
P2860
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P2860
Two cyclin-dependent kinase pathways are essential for polarized trafficking of presynaptic components
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
name
Two cyclin-dependent kinase pa ...... king of presynaptic components
@ast
Two cyclin-dependent kinase pa ...... king of presynaptic components
@en
type
label
Two cyclin-dependent kinase pa ...... king of presynaptic components
@ast
Two cyclin-dependent kinase pa ...... king of presynaptic components
@en
prefLabel
Two cyclin-dependent kinase pa ...... king of presynaptic components
@ast
Two cyclin-dependent kinase pa ...... king of presynaptic components
@en
P2093
P2860
P1433
P1476
Two cyclin-dependent kinase pa ...... king of presynaptic components
@en
P2093
Amy K Y Fu
Celine I Maeder
Chan-Yen Ou
Emily K Lehrman
Erik M Jorgensen
Mikyoung Park
Nancy Y Ip
Shigeki Watanabe
Vivian Y Poon
P2860
P304
P356
10.1016/J.CELL.2010.04.011
P407
P577
2010-05-01T00:00:00Z