about
KATNAL1 regulation of sertoli cell microtubule dynamics is essential for spermiogenesis and male fertilityImpaired synaptic plasticity and motor learning in mice with a point mutation implicated in human speech deficitsReciprocal interactions between circadian clocks and agingAnalysis of Individual Mouse Activity in Group Housed Animals of Different Inbred Strains using a Novel Automated Home Cage Analysis SystemNovel gene function revealed by mouse mutagenesis screens for models of age-related disease.Melanopsin Regulates Both Sleep-Promoting and Arousal-Promoting Responses to LightMutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouseThe Regulatory Factor ZFHX3 Modifies Circadian Function in SCN via an AT Motif-Driven AxisDissecting the genetic complexity of human 6p deletion syndromes by using a region-specific, phenotype-driven mouse screen.Mutations in gasdermin 3 cause aberrant differentiation of the hair follicle and sebaceous glandDistinct and separable roles for endogenous CRY1 and CRY2 within the circadian molecular clockwork of the suprachiasmatic nucleus, as revealed by the Fbxl3(Afh) mutation.Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt-PCP-JNK pathwayAnalysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinicsGenetic background influences age-related decline in visual and nonvisual retinal responses, circadian rhythms, and sleep.Dominant β-catenin mutations cause intellectual disability with recognizable syndromic features.A point mutation in TRPC3 causes abnormal Purkinje cell development and cerebellar ataxia in moonwalker mice.Reliability, robustness, and reproducibility in mouse behavioral phenotyping: a cross-laboratory studyInformatics for mutagenesis: the design of mutabase--a distributed data recording system for animal husbandry, mutagenesis, and phenotypic analysis.A novel SOD1-ALS mutation separates central and peripheral effects of mutant SOD1 toxicityMouse mutagenesis-systematic studies of mammalian gene function.When clocks go bad: neurobehavioural consequences of disrupted circadian timing.Stringent requirement of a proper level of canonical WNT signalling activity for head formation in mouse embryo.Reduced anxiety and depression-like behaviours in the circadian period mutant mouse afterhoursOverexpression of Fto leads to increased food intake and results in obesityMutations in alpha-tubulin cause abnormal neuronal migration in mice and lissencephaly in humans.Polymorphisms in the circadian expressed genes PER3 and ARNTL2 are associated with diurnal preference and GNβ3 with sleep measuresSleep-like behavior and 24-h rhythm disruption in the Tc1 mouse model of Down syndromeN-ethyl-N-nitrosourea mouse mutants in the dissection of behavioural and psychiatric disorders.Defining the cause of skewed X-chromosome inactivation in X-linked mental retardation by use of a mouse modelENU mutagenesis in the mouse: application to human genetic disease.The role of mutagenesis in defining genes in behaviour.Early doors (Edo) mutant mouse reveals the importance of period 2 (PER2) PAS domain structure for circadian pacemaking.Three novel pigmentation mutants generated by genome-wide random ENU mutagenesis in the mouseA twin and molecular genetics study of sleep paralysis and associated factorsGenetic and molecular analysis of the central and peripheral circadian clockwork of mice.Clocks go forward: progress in the molecular genetic analysis of rhythmic behaviour.Cognitive assessment of mice strains heterozygous for cell-adhesion genes reveals strain-specific alterations in timing.Early motor deficits in mouse disease models are reliably uncovered using an automated home-cage wheel-running system: a cross-laboratory validation.Implementation of a large-scale ENU mutagenesis program: towards increasing the mouse mutant resource.Random mutagenesis screen for dominant behavioral mutations in mice.
P50
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Patrick M Nolan
@nl
Patrick M Nolan
@sl
Patrick M. Nolan
@en
Patrick M. Nolan
@es
Patrick Nolan
@fr
type
label
Patrick M Nolan
@nl
Patrick M Nolan
@sl
Patrick M. Nolan
@en
Patrick M. Nolan
@es
Patrick Nolan
@fr
prefLabel
Patrick M Nolan
@nl
Patrick M Nolan
@sl
Patrick M. Nolan
@en
Patrick M. Nolan
@es
Patrick Nolan
@fr
P106
P1153
7202342550
P21
P2798
P31
P496
0000-0001-5550-0334