about
A domain-oriented approach to the reduction of combinatorial complexity in signal transduction networksPseudophosphatase STYX modulates cell-fate decisions and cell migration by spatiotemporal regulation of ERK1/2MAPK kinase signalling dynamics regulate cell fate decisions and drug resistanceG Protein-Coupled Receptor Signaling Networks from a Systems PerspectiveSwitches, excitable responses and oscillations in the Ring1B/Bmi1 ubiquitination systemVersatility of cooperative transcriptional activation: a thermodynamical modeling analysis for greater-than-additive and less-than-additive effectsMitogen-Inducible Gene-6 Mediates Feedback Inhibition from Mutated BRAF towards the Epidermal Growth Factor Receptor and Thereby Limits Malignant TransformationProbing the Heterogeneity of Protein Kinase Activation in Cells by Super-resolution MicroscopySignalling ballet in space and timeEvaluating strategies to normalise biological replicates of Western blot data.Navigating the multilayered organization of eukaryotic signaling: a new trend in data integration.Multistrip Western blotting to increase quantitative data output.Inferring dynamic architecture of cellular networks using time series of gene expression, protein and metabolite data.Positional information generated by spatially distributed signaling cascades.Cellular information transfer regarded from a stoichiometry and control analysis perspective.Why cytoplasmic signalling proteins should be recruited to cell membranes.PI3K/Akt-sensitive MEK-independent compensatory circuit of ERK activation in ER-positive PI3K-mutant T47D breast cancer cellsFormation of intracellular concentration landscapes by multisite protein modification.Four-dimensional organization of protein kinase signaling cascades: the roles of diffusion, endocytosis and molecular motors.Untangling the wires: a strategy to trace functional interactions in signaling and gene networks.Signaling through receptors and scaffolds: independent interactions reduce combinatorial complexityWhen ubiquitination meets phosphorylation: a systems biology perspective of EGFR/MAPK signalling.Complexity of receptor tyrosine kinase signal processing.Emergence of bimodal cell population responses from the interplay between analog single-cell signaling and protein expression noise.The dynamic control of signal transduction networks in cancer cells.Cell-signalling dynamics in time and space.Nonlinear signalling networks and cell-to-cell variability transform external signals into broadly distributed or bimodal responses.MAP kinase cascade signaling and endocytic trafficking: a marriage of convenience?Trading the micro-world of combinatorial complexity for the macro-world of protein interaction domains.Integrating Bayesian variable selection with Modular Response Analysis to infer biochemical network topologyCompeting to coordinate cell fate decisions: the MST2-Raf-1 signaling deviceProlactin-stimulated activation of ERK1/2 mitogen-activated protein kinases is controlled by PI3-kinase/Rac/PAK signaling pathway in breast cancer cells.Long-range signaling by phosphoprotein waves arising from bistability in protein kinase cascades.Signalling mechanisms regulating phenotypic changes in breast cancer cells.The ErbB4 CYT2 variant protects EGFR from ligand-induced degradation to enhance cancer cell motility.Quantitative analysis of signaling networks.DYVIPAC: an integrated analysis and visualisation framework to probe multi-dimensional biological networks.Signalling by protein phosphatases and drug development: a systems-centred view.Ligand-dependent responses of the ErbB signaling network: experimental and modeling analyses.Frequency modulation of ERK activation dynamics rewires cell fate.
P50
Q21284247-E604B882-5A63-48B3-BDDD-59E6333EDF07Q24307792-8FB617AC-14BB-4494-9A03-A02E90434E73Q26859721-DA520330-754A-4E04-A908-A99227872326Q26866305-291C41DD-13DA-4792-BDB7-46E2C6E76F25Q28478440-7BE847B1-B842-49D8-AFF7-2AC0DDAF333BQ28482233-7860FD0B-91F5-4F1E-B55D-0748FD3DA872Q28548302-DE57CD7C-EEA7-4074-A1DE-B85D73EC2F6EQ30364872-C19FF2AD-2946-4486-9EF4-2841D1585650Q30497330-67B78B6C-2F68-4BCF-A711-18F7C9657494Q30744839-45CA856D-1EE3-4CB3-B700-CA83AC970346Q30759763-4C9791DE-5085-4396-8A32-204DD1D46ADAQ31122708-5989B19D-D19D-4BA7-AC9C-8751AB3CC532Q33200015-195AB7A7-4383-4C2E-9DE2-B87A5CA9172DQ33419848-185F2424-2021-45D6-A6B3-743B0390D42AQ33879898-362E9521-194F-462D-A9DB-5AE9FB85B894Q33885449-CEBF5BFC-F32C-4A59-BBF5-AFEA5D9BBEBAQ33945648-4410A77F-6A34-4A37-B46F-3EA9954204D9Q33954366-903991AC-B5C0-425E-B0D5-FACF8D8FD049Q33966121-001AC3FE-7627-40D9-9D62-676357DAF85FQ34190157-DEB66F5E-5023-40B5-8AA2-E618381BB761Q34350920-1B140780-3DE6-47F5-9BFE-C97DA93A0504Q34360923-27F0975A-76B1-43C2-B2D2-CA8702B13D86Q34361161-AB9EA0FD-00A5-4E90-98CB-9FFE548CB6D7Q34393131-F5174637-38CE-4394-9782-AC2C4D75C2F8Q34490200-71E53DB0-4E28-44BA-83C7-CE569551EECFQ34495098-7474E68A-ADF5-4793-B1F0-4F03A3944777Q34520921-3A8AAF6A-5363-4D09-B421-911750FD85FAQ34616017-6138078F-4F4F-4FBD-91F2-46A139D13100Q34672597-25BADE71-0A47-427D-805D-B40A88FC42DEQ34800432-A0EDB506-9C4D-4100-BED6-EC8BA45B5196Q35158033-8F11C214-F952-430E-B868-791638F4BAEFQ35165105-9CA90C6A-A661-4062-8973-5DB07C4583D8Q35194030-688B40FE-93C9-4669-A1E5-7D98708C6D14Q35207250-2231F982-F603-4067-90F0-38E4816439E1Q35228445-554E1CB9-7226-4948-8F6B-FAC2EA1BA395Q35839975-40A24074-F98B-423D-9C9D-18C836BF8332Q35898222-416F9EC9-F31F-4917-8E49-308ECC1AF7EAQ36012977-FE46F40B-459E-4079-8E53-37A6082EB6AAQ36254464-A00B0E2A-92E5-4920-BD0B-F4733779B30DQ36349325-0D3B5574-E15C-489A-987A-0A7BD6C00779
P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Boris Kholodenko
@en
Boris Kholodenko
@fr
Boris N Kholodenko
@nl
Boris N Kholodenko
@sl
Boris N. Kholodenko
@es
Boris Naumowitsch Cholodenko
@de
Борис Наумович Холоденко
@ru
type
label
Boris Kholodenko
@en
Boris Kholodenko
@fr
Boris N Kholodenko
@nl
Boris N Kholodenko
@sl
Boris N. Kholodenko
@es
Boris Naumowitsch Cholodenko
@de
Борис Наумович Холоденко
@ru
altLabel
Boris Cholodenko
@de
Boris N. Kholodenko
@en
Boris Naumovich Kholodenko
@en
prefLabel
Boris Kholodenko
@en
Boris Kholodenko
@fr
Boris N Kholodenko
@nl
Boris N Kholodenko
@sl
Boris N. Kholodenko
@es
Boris Naumowitsch Cholodenko
@de
Борис Наумович Холоденко
@ru
P106
P1153
7005285452
P21
P2456
P2798
P31
P496
0000-0002-9483-4975