Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization. - sprookjes - yvandenbroek - TriplyDB

Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization.

Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization.

http://www.wikidata.org/entity/Q30579125

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Effect of hypoxia on the expression of αB-crystallin in head and neck squamous cell carcinoma Adenosine and hypoxia-inducible factor signaling in intestinal injury and recovery Hypoxia-inducible factors and the response to hypoxic stress Role of hypoxia and vascular endothelial growth factors in lymphangiogenesis Anti-angiogenesis or pro-angiogenesis for cancer treatment: focus on drug distribution Molecular control of capillary morphogenesis and maturation by recognition and remodeling of the extracellular matrix: functional roles of endothelial cells and pericytes in health and disease Menstrual physiology: implications for endometrial pathology and beyond Anti-angiogenesis and metastasis: a tumour and stromal cell alliance Hypoxia-mediated regulation of macrophage functions in pathophysiology Tumor endothelial cells Broad targeting of angiogenesis for cancer prevention and therapy Molecular control of endothelial cell behaviour during blood vessel morphogenesis Resistance and escape from antiangiogenesis therapy: clinical implications and future strategies The clinical importance of assessing tumor hypoxia: relationship of tumor hypoxia to prognosis and therapeutic opportunities Fibroblast Growth Factor 9 Imparts Hierarchy and Vasoreactivity to the Microcirculation of Renal Tumors and Suppresses Metastases Hypoxia: an alarm signal during intestinal inflammation PHD2: from hypoxia regulation to disease progression Vascular Transdifferentiation in the CNS: A Focus on Neural and Glioblastoma Stem-Like Cells Targeting tumor-associated macrophages to combat pancreatic cancer The ever-expanding role of HIF in tumour and stromal biology Technologies for controlled, local delivery of siRNA Prolyl hydroxylase-2 (PHD2) exerts tumor-suppressive activity in pancreatic cancer Prolyl hydroxylase domain 2 protein is a strong prognostic marker in human gastric cancer Influence of cell detachment on the respiration rate of tumor and endothelial cells CLN3 deficient cells display defects in the ARF1-Cdc42 pathway and actin-dependent events Local guidance of emerging vessel sprouts requires soluble Flt-1 Microenvironmental Heterogeneity Parallels Breast Cancer Progression: A Histology-Genomic Integration Analysis Life history trade-offs in cancer evolution How cancer shapes evolution, and how evolution shapes cancer Targeting PI3K in cancer: impact on tumor cells, their protective stroma, angiogenesis and immunotherapy Molecular mechanisms and clinical applications of angiogenesis Clonal evolution in cancer Subcellular Energetics and Metabolism: Potential Therapeutic Applications.Antiangiogenesis strategies revisited: from starving tumors to alleviating hypoxia.Integration of experimental and computational approaches to sprouting angiogenesis.Cellular characterization of ultrasound-stimulated microbubble radiation enhancement in a prostate cancer xenograft model.Vascular normalization as a therapeutic strategy for malignant and nonmalignant disease.Normalization of the vasculature for treatment of cancer and other diseases.Identification and characterization of a resident vascular stem/progenitor cell population in preexisting blood vessels.CYSL-1 interacts with the O2-sensing hydroxylase EGL-9 to promote H2S-modulated hypoxia-induced behavioral plasticity in C. elegans.

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Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization.

http://www.wikidata.org/entity/Q30579125

description

2009 nî lūn-bûn

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2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի փետրվարին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

Heterozygous deficiency of PHD ...... via endothelial normalization.

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Heterozygous deficiency of PHD ...... via endothelial normalization.

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type

label

Heterozygous deficiency of PHD ...... via endothelial normalization.

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Heterozygous deficiency of PHD ...... via endothelial normalization.

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prefLabel

Heterozygous deficiency of PHD ...... via endothelial normalization.

@ast

Heterozygous deficiency of PHD ...... via endothelial normalization.

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J.CELL.2009.01.020

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Heterozygous deficiency of PHD ...... via endothelial normalization.

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Alberto Pisacane

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Anthony A Lanahan

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Bart Jonckx

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Benedicte Jordan

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Bernard Gallez

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Carmen Ruiz de Almodovar

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Daniela Dettori

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Julián Aragonés

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Koen Debackere

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Sabine Wyns

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P2860

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

Anti-PlGF inhibits growth of VEGF(R)-inhibitor-resistant tumors without affecting healthy vessels

Contact inhibition of VEGF-induced proliferation requires vascular endothelial cadherin, beta-catenin, and the phosphatase DEP-1/CD148

Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability

Modes of resistance to anti-angiogenic therapy

Deletion of vascular endothelial growth factor in myeloid cells accelerates tumorigenesis

Targeting HIF-1 for cancer therapy

Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis

The VEGF receptor flt-1 (VEGFR-1) is a positive modulator of vascular sprout formation and branching morphogenesis

The transcription factor EPAS-1/hypoxia-inducible factor 2alpha plays an important role in vascular remodeling

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136

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Peter Carmeliet

Peter J. Ratcliffe

Massimiliano Mazzone

Patrick H Maxwell

Frederik De Smet

Patrick J Pollard

Maria Grazia Lampugnani

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2009-02-12T00:00:00Z

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