A rise in NAD precursor nicotinamide mononucleotide (NMN) after injury promotes axon degeneration
about
Traumatic Axonal Injury: Mechanisms and Translational OpportunitiesSome reminiscences on studies of age-dependent and activity-dependent degeneration of sensory and motor endings in mammalian skeletal muscleActivation of SIRT3 by the NAD⁺ precursor nicotinamide riboside protects from noise-induced hearing lossVitamin B3 modulates mitochondrial vulnerability and prevents glaucoma in aged miceActivity-dependent degeneration of axotomized neuromuscular synapses in Wld S mice.Absence of SARM1 rescues development and survival of NMNAT2-deficient axons.Short-term diabetic hyperglycemia suppresses celiac ganglia neurotransmission, thereby impairing sympathetically mediated glucagon responses.Local axonal protection by WldS as revealed by conditional regulation of protein stability.NMNAT2:HSP90 Complex Mediates Proteostasis in Proteinopathies.Mitochondria and Caspases Tune Nmnat-Mediated Stabilization to Promote Axon RegenerationNMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD+ depletion.Axon Self-Destruction: New Links among SARM1, MAPKs, and NAD+ Metabolism.Glaucoma as a Metabolic Optic Neuropathy: Making the Case for Nicotinamide Treatment in Glaucoma.Nicotinamide Adenine Dinucleotide Metabolism and Neurodegeneration.Inhibitor of Nicotinamide Phosphoribosyltransferase Sensitizes Glioblastoma Cells to Temozolomide via Activating ROS/JNK Signaling Pathway.Molecular mechanisms in the initiation phase of Wallerian degeneration.Axon degeneration: context defines distinct pathways.Roles of palmitoylation in axon growth, degeneration and regeneration.Nicotinamide mononucleotide inhibits post-ischemic NAD(+) degradation and dramatically ameliorates brain damage following global cerebral ischemia.A Mechanistic Understanding of Axon Degeneration in Chemotherapy-Induced Peripheral Neuropathy.Deletion of Sarm1 gene is neuroprotective in two models of peripheral neuropathy.The axon-protective WLD(S) protein partially rescues mitochondrial respiration and glycolysis after axonal injury.Avian axons undergo Wallerian degeneration after injury and stress.A neuroprotective agent that inactivates prodegenerative TrkA and preserves mitochondria.NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR.Role of SARM1 and DR6 in retinal ganglion cell axonal and somal degeneration following axonal injury.The Influence of Nicotinamide on Health and Disease in the Central Nervous System.The Axon-Myelin Unit in Development and Degenerative Diseaseβ-nicotinamide mononucleotide (NMN) production in Escherichia coli
P2860
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P2860
A rise in NAD precursor nicotinamide mononucleotide (NMN) after injury promotes axon degeneration
description
2014 nî lūn-bûn
@nan
2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
A rise in NAD precursor nicoti ...... ury promotes axon degeneration
@ast
A rise in NAD precursor nicoti ...... ury promotes axon degeneration
@en
type
label
A rise in NAD precursor nicoti ...... ury promotes axon degeneration
@ast
A rise in NAD precursor nicoti ...... ury promotes axon degeneration
@en
prefLabel
A rise in NAD precursor nicoti ...... ury promotes axon degeneration
@ast
A rise in NAD precursor nicoti ...... ury promotes axon degeneration
@en
P2093
P2860
P50
P356
P1476
A rise in NAD precursor nicoti ...... ury promotes axon degeneration
@en
P2093
I Nascimento-Ferreira
J R M Webster
L A Worrell
P2860
P2888
P304
P356
10.1038/CDD.2014.164
P577
2014-10-17T00:00:00Z