Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex.
about
Autocrine WNT signaling contributes to breast cancer cell proliferation via the canonical WNT pathway and EGFR transactivationNHERF1/EBP50 head-to-tail intramolecular interaction masks association with PDZ domain ligandsThe ubiquitin-specific protease USP34 regulates axin stability and Wnt/β-catenin signalingThermodynamics of beta-catenin-ligand interactions: the roles of the N- and C-terminal tails in modulating binding affinitySmall molecule inhibitors of Wnt/beta-catenin/lef-1 signaling induces apoptosis in chronic lymphocytic leukemia cells in vitro and in vivoDACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modificationsWnt/beta-catenin signaling and small molecule inhibitorsWnt/beta-catenin signaling: components, mechanisms, and diseasesTargeted disruption of the BCL9/β-catenin complex inhibits oncogenic Wnt signalingThe Wnt-dependent signaling pathways as target in oncology drug discoveryAdvances in targeted and immunobased therapies for colorectal cancer in the genomic eraTargeting Wnt/β-catenin pathway in hepatocellular carcinoma treatmentModulation of Protein-Protein Interactions for the Development of Novel TherapeuticsPolyphenol Compound as a Transcription Factor InhibitorDevelopment of anticancer agents targeting the Wnt/β-catenin signalingSignaling in Fibrosis: TGF-β, WNT, and YAP/TAZ ConvergeFlavonoids and Wnt/β-catenin signaling: potential role in colorectal cancer therapiesEmerging role of the β-catenin-PPARγ axis in the pathogenesis of colorectal cancerWnt signalling in smooth muscle cells and its role in cardiovascular disordersTargeting the Wnt pathway in human cancers: therapeutic targeting with a focus on OMP-54F28Features of protein-protein interactions that translate into potent inhibitors: topology, surface area and affinityMolecular therapy of colorectal cancer: progress and future directionsInhibition of oncogenic Wnt signaling through direct targeting of -cateninIn vitro models of cancer stem cells and clinical applicationsWnt/β-catenin signalling in prostate cancerThe SCF ubiquitin ligase: insights into a molecular machineSuppression of Wnt signaling by the green tea compound (-)-epigallocatechin 3-gallate (EGCG) in invasive breast cancer cells. Requirement of the transcriptional repressor HBP1Norcantharidin, derivative of cantharidin, for cancer stem cellsDickkopfs and Wnt/β-catenin signalling in liver cancerInhibition of melanogenesis by the pyridinyl imidazole class of compounds: possible involvement of the Wnt/β-catenin signaling pathwaySmall molecule antagonists of the Wnt/β-catenin signaling pathway target breast tumor-initiating cells in a Her2/Neu mouse model of breast cancerSynergistic effects of combined Wnt/KRAS inhibition in colorectal cancer cellsWnt/beta-catenin signaling is required for development of the exocrine pancreasDerricin and derricidin inhibit Wnt/β-catenin signaling and suppress colon cancer cell growth in vitroA potent and selective small molecule inhibitor of sirtuin 1 promotes differentiation of pluripotent P19 cells into functional neuronsWNT and beta-catenin signalling: diseases and therapiesA novel ent-kaurane diterpenoid executes antitumor function in colorectal cancer cells by inhibiting Wnt/β-catenin signaling.Modulating protein-protein interactions with small molecules: the importance of binding hotspots.Linking proteomic and transcriptional data through the interactome and epigenome reveals a map of oncogene-induced signaling.A small molecule inhibitor of beta-catenin/CREB-binding protein transcription [corrected]
P2860
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P2860
Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex.
description
2004 nî lūn-bûn
@nan
2004 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex.
@ast
Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex.
@en
type
label
Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex.
@ast
Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex.
@en
prefLabel
Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex.
@ast
Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex.
@en
P2093
P1433
P1476
Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex.
@en
P2093
Alexander W Wood
Charles Bruseo
Dennis S France
Frank Petersen
Huisheng Wang
Maina Lepourcelet
Phillip Crews
Ramesh A Shivdasani
Ying-Nan P Chen
P304
P356
10.1016/S1535-6108(03)00334-9
P577
2004-01-01T00:00:00Z