Reverse dosimetry: interpreting trihalomethanes biomonitoring data using physiologically based pharmacokinetic modeling. - sprookjes - yvandenbroek - TriplyDB

Reverse dosimetry: interpreting trihalomethanes biomonitoring data using physiologically based pharmacokinetic modeling.

Reverse dosimetry: interpreting trihalomethanes biomonitoring data using physiologically based pharmacokinetic modeling.

http://www.wikidata.org/entity/Q31077784

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Nanotechnology-based electrochemical sensors for biomonitoring chemical exposures Animal-Free Chemical Safety Assessment Toxicity testing in the 21 century: defining new risk assessment approaches based on perturbation of intracellular toxicity pathways Developing a Physiologically-Based Pharmacokinetic Model Knowledgebase in Support of Provisional Model Construction Incorporating new technologies into toxicity testing and risk assessment: moving from 21st century vision to a data-driven framework.Computational toxicology of chloroform: reverse dosimetry using Bayesian inference, Markov chain Monte Carlo simulation, and human biomonitoring data.Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010.Development of screening tools for the interpretation of chemical biomonitoring data Reconstruction of Exposure to m-Xylene from Human Biomonitoring Data Using PBPK Modelling, Bayesian Inference, and Markov Chain Monte Carlo Simulation.An assessment of the interindividual variability of internal dosimetry during multi-route exposure to drinking water contaminants.Reconstructing population exposures to environmental chemicals from biomarkers: challenges and opportunities.Variation in urinary flow rates according to demographic characteristics and body mass index in NHANES: potential confounding of associations between health outcomes and urinary biomarker concentrations Application of physiologically based pharmacokinetic models in chemical risk assessment.A probabilistic model of human variability in physiology for future application to dose reconstruction and QIVIVE.Incorporating High-Throughput Exposure Predictions With Dosimetry-Adjusted In Vitro Bioactivity to Inform Chemical Toxicity Testing.In vitro screening for population variability in toxicity of pesticide-containing mixtures PROcEED: Probabilistic reverse dosimetry approaches for estimating exposure distributions.Exposure as part of a systems approach for assessing risk Challenges in the application of quantitative approaches in risk assessment: a case study with di-(2-ethylhexyl)phthalate.Reconstructing human exposures using biomarkers and other "clues".Characterization of the human kinetic adjustment factor for the health risk assessment of environmental contaminants.A Method for Identifying Prevalent Chemical Combinations in the U.S. Population.Identifying populations sensitive to environmental chemicals by simulating toxicokinetic variability.Contribution of inorganic arsenic sources to population exposure risk on a regional scale.Development and application of a human PBPK model for bromodichloromethane to investigate the impacts of multi-route exposure.Predicting human exposure and risk from chlorinated indoor swimming pool: a case study.Incorporating population variability and susceptible subpopulations into dosimetry for high-throughput toxicity testing.Occurrence of disinfection by-products in tap water distribution systems and their associated health risk.Public health interpretation of trihalomethane blood levels in the United States: NHANES 1999-2004.Translational research to develop a human PBPK models tool kit-volatile organic compounds (VOCs).Reconstructing exposures from small samples using physiologically based pharmacokinetic models and multiple biomarkers.Occurrences and changes of disinfection by-products in small water supply systems.Interpreting PCB levels in breast milk using a physiologically based pharmacokinetic model to reconstruct the dynamic exposure of Italian women.A decision tree approach to screen drinking water contaminants for multiroute exposure potential in developing guideline values.Accounting for the impact of short-term variations in the levels of trihalomethane in drinking water on exposure assessment for epidemiological purposes. Part II: biological aspects.A Computational Workflow for Probabilistic Quantitative in Vitro to in Vivo Extrapolation.httk: R Package for High-Throughput Toxicokinetics Trihalomethanes in desalinated water: Human exposure and risk analysis Impact of source waters, disinfectants, seasons and treatment approaches on trihalomethanes in drinking water: a comparison based on the size of municipal systems Implications of Using Steady-State Conditions in Estimating Dermal Uptake of Volatile Compounds in Municipal Drinking Water: An Example of THMs

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Reverse dosimetry: interpreting trihalomethanes biomonitoring data using physiologically based pharmacokinetic modeling.

http://www.wikidata.org/entity/Q31077784

description

2006 nî lūn-bûn

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2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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Journal of Exposure Analysis and Environmental Epidemiology

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Harvey J Clewell

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Kai H Liao

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Yu-Mei Tan

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P2860

Influence of tap water quality and household water use activities on indoor air and internal dose levels of trihalomethanes.

A revised probabilistic estimate of the maternal methyl mercury intake dose corresponding to a measured cord blood mercury concentration.

Use of a physiologically based pharmacokinetic model to identify exposures consistent with human biomonitoring data for chloroform.

Chlorination disinfection byproducts in water and their association with adverse reproductive outcomes: a review.

Development of a physiologically based pharmacokinetic model of trichloroethylene and its metabolites for use in risk assessment.

Exposure reconstruction for the TCDD-exposed NIOSH cohort using a concentration- and age-dependent model of elimination.

Changes in breath trihalomethane levels resulting from household water-use activities

Evaluation of dermal and respiratory chloroform exposure in humans

Assessment of airborne exposure to trihalomethanes from tap water in residential showers and baths.

Reconstructing population exposures from dose biomarkers: inhalation of trichloroethylene (TCE) as a case study.

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10.1038/SJ.JES.7500540

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