A central role for GRB10 in regulation of islet function in man.
about
Amelioration of Diabetic Mouse Nephropathy by Catalpol Correlates with Down-Regulation of Grb10 Expression and Activation of Insulin-Like Growth Factor 1 / Insulin-Like Growth Factor 1 Receptor SignalingGenetics of Type 2 Diabetes: the Power of Isolated Populations.Genetic Regulation of Adipose Gene Expression and Cardio-Metabolic Traits.Tissue-specific regulation and function of Grb10 during growth and neuronal commitment.Transcript Expression Data from Human Islets Links Regulatory Signals from Genome-Wide Association Studies for Type 2 Diabetes and Glycemic Traits to Their Downstream Effectors.Genome-wide associations between genetic and epigenetic variation influence mRNA expression and insulin secretion in human pancreatic islets.Frugal fat or munificent muscle: genomic imprinting and metabolism.Identification and validation of N-acetyltransferase 2 as an insulin sensitivity geneCarrageenan Inhibits Insulin Signaling through GRB10-mediated Decrease in Tyr(P)-IRS1 and through Inflammation-induced Increase in Ser(P)307-IRS1Impact of PTBP1 rs11085226 on glucose-stimulated insulin release in adult Danes.Evidence of a Causal Association Between Insulinemia and Endometrial Cancer: A Mendelian Randomization Analysis.Epigenetic Alterations in Human Liver From Subjects With Type 2 Diabetes in Parallel With Reduced Folate LevelsEvaluation of type 2 diabetes genetic risk variants in Chinese adults: findings from 93,000 individuals from the China Kadoorie Biobank.Improved Performance of Dynamic Measures of Insulin Response Over Surrogate Indices to Identify Genetic Contributors of Type 2 Diabetes: The GUARDIAN Consortium.Tissue-specific regulatory circuits reveal variable modular perturbations across complex diseasesInsights into the genetic susceptibility to type 2 diabetes from genome-wide association studies of glycaemic traits.Mechanisms of Type 2 Diabetes Risk Loci.Tau deletion promotes brain insulin resistanceAn Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.Common and rare forms of diabetes mellitus: towards a continuum of diabetes subtypes.Genetics of Type 2 Diabetes: It Matters From Which Parent We Inherit the Risk.Excess maternal transmission of variants in the THADA gene to offspring with type 2 diabetes.A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants.The Metabolic Syndrome in Men study: a resource for studies of metabolic and cardiovascular diseases.Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance.The PI3K Pathway in Human Disease.Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness.Ranking factors involved in diabetes remission after bariatric surgery using machine-learning integrating clinical and genomic biomarkers.Genetic Evidence That Carbohydrate-Stimulated Insulin Secretion Leads to Obesity.Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion: A DIRECT study.Biochemical and cellular properties of insulin receptor signalling.Disentangling the Role of Melatonin and its Receptor MTNR1B in Type 2 Diabetes: Still a Long Way to Go?Genetic analysis in UK Biobank links insulin resistance and transendothelial migration pathways to coronary artery disease.Genetic aetiology of glycaemic traits: approaches and insights.Genetic variants in sex hormone pathways and the risk of type 2 diabetes among African-American, Hispanic-American, and European-American postmenopausal women in the United States.New approaches beyond genetics: towards precision medicine in diabetes.Epigenetic marks of in utero exposure to gestational diabetes and childhood adiposity outcomes: the EPOCH study.Does epigenetic dysregulation of pancreatic islets contribute to impaired insulin secretion and type 2 diabetes?Genetic risk score of common genetic variants for impaired fasting glucose and newly diagnosed type 2 diabetes influences oxidative stress.An adult-based insulin resistance genetic risk score associates with insulin resistance, metabolic traits and altered fat distribution in Danish children and adolescents who are overweight or obese
P2860
Q27316814-381DED3C-CD07-427D-972B-00B59DA2DC34Q30250281-6A2A755C-2E65-4844-B1B8-8BB6264B4B09Q30253043-B3FCC688-FE3F-4FF6-999E-795C7E5452DBQ30653788-C850CEDD-AB85-429C-8024-4E1A9A3F8BB9Q31029687-FF75C3CC-566D-4BCA-8FFA-0A82BC383833Q34464568-91FE3D66-DF65-48AC-B427-3F9B498B24ECQ34794255-520493D9-8794-47F7-A787-117E6E09D3A0Q35535617-B5773EF9-2167-4499-AEE7-51C31F2504D3Q35536252-A77F025B-28A1-45AE-88D1-551336C83672Q35575791-981BE0ED-57F1-4279-B80D-39AD7F15FB7AQ36067788-42A3D818-4D9F-4B73-A9BB-075A42D7D4DEQ36433576-EB177435-82D9-4912-8D38-2FCD230385FCQ36990114-59311527-9B85-42B2-BDE1-AB9A3640D8DCQ37025657-D3115976-7FC4-4B85-B4A4-91C6D9340DA9Q37140821-E9257609-E4B8-48D2-BFAA-CD8133DB0C92Q38262599-701D9EF1-BEBB-4699-9C06-349F73FC60ADQ38652238-022DECA8-F175-4A12-AEF9-FF1A78B8A491Q38708062-429B67B9-7EE3-41AF-ACEB-BC56E0A36B9BQ38752732-9413FF2B-1AC1-4802-9FFA-25F30442D2F9Q38808702-E353E816-357F-49FC-800E-0F6A2B8D3F8AQ38816589-75C5DC23-4A86-4FC6-94A1-ACAA34FAF2EAQ39786100-62C2FF06-FF5D-4901-B278-81E2CC89DED9Q40206988-D780D0DC-5127-4164-B460-76D8DFA51911Q40365893-BC88B3B7-8F89-47C8-9D28-662FF59F75A2Q40476668-F2BA650F-9FB2-4297-9A6E-639E0AA6F3FCQ46546002-0A35600A-3084-45BE-8828-875D3CC6DDDDQ46956167-C1C64C18-F6FE-4CFE-B18F-CC103756E1BAQ47105166-705A69C4-E2EC-4938-A45C-F4067C9194ACQ47218060-93F397EA-DC05-4639-837B-5A7A9637FAD4Q47238942-7B713629-A4E3-4B8A-9011-1F1334544D1CQ47703395-28505C37-D5B1-4AC7-A3E6-1D4DDE8D2A7CQ47732906-7B05B1CE-5F61-477A-909D-C638084C52D0Q48116001-4FB24615-2BB1-4EFB-918B-33C80FEC4B57Q49608463-28F206D6-16ED-4294-A2AF-B84B4DD8BB11Q50124738-ED784171-B421-43B8-9CA5-F47586C4EE43Q51453008-75723E74-8A67-4637-8BEA-22E9E88AE816Q52731398-1855DC70-5BBE-498F-B3B2-76778F932451Q53345467-E8B66A4C-4D34-469A-B824-5831475E231DQ54948885-1ED37567-944E-4415-9709-42774EBD0312Q57401668-1E939CAA-6820-4B18-8D18-5330B6C3F65F
P2860
A central role for GRB10 in regulation of islet function in man.
description
2014 nî lūn-bûn
@nan
2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
A central role for GRB10 in regulation of islet function in man.
@ast
A central role for GRB10 in regulation of islet function in man.
@en
type
label
A central role for GRB10 in regulation of islet function in man.
@ast
A central role for GRB10 in regulation of islet function in man.
@en
prefLabel
A central role for GRB10 in regulation of islet function in man.
@ast
A central role for GRB10 in regulation of islet function in man.
@en
P2093
P2860
P50
P1433
P1476
A central role for GRB10 in regulation of islet function in man.
@en
P2093
Adam Barker
Andrea Mari
Cecile Lecoeur
Claire Levy-Marchal
Elisabeth Widen
Emma Ahlqvist
Hyun Min Kang
Jalal Taneera
Jeffrey R O'Connell
P2860
P304
P356
10.1371/JOURNAL.PGEN.1004235
P50
P577
2014-04-03T00:00:00Z