A central role for GRB10 in regulation of islet function in man. - sprookjes - yvandenbroek - TriplyDB

A central role for GRB10 in regulation of islet function in man.

A central role for GRB10 in regulation of islet function in man.

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Amelioration of Diabetic Mouse Nephropathy by Catalpol Correlates with Down-Regulation of Grb10 Expression and Activation of Insulin-Like Growth Factor 1 / Insulin-Like Growth Factor 1 Receptor Signaling Genetics of Type 2 Diabetes: the Power of Isolated Populations.Genetic Regulation of Adipose Gene Expression and Cardio-Metabolic Traits.Tissue-specific regulation and function of Grb10 during growth and neuronal commitment.Transcript Expression Data from Human Islets Links Regulatory Signals from Genome-Wide Association Studies for Type 2 Diabetes and Glycemic Traits to Their Downstream Effectors.Genome-wide associations between genetic and epigenetic variation influence mRNA expression and insulin secretion in human pancreatic islets.Frugal fat or munificent muscle: genomic imprinting and metabolism.Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene Carrageenan Inhibits Insulin Signaling through GRB10-mediated Decrease in Tyr(P)-IRS1 and through Inflammation-induced Increase in Ser(P)307-IRS1 Impact of PTBP1 rs11085226 on glucose-stimulated insulin release in adult Danes.Evidence of a Causal Association Between Insulinemia and Endometrial Cancer: A Mendelian Randomization Analysis.Epigenetic Alterations in Human Liver From Subjects With Type 2 Diabetes in Parallel With Reduced Folate Levels Evaluation of type 2 diabetes genetic risk variants in Chinese adults: findings from 93,000 individuals from the China Kadoorie Biobank.Improved Performance of Dynamic Measures of Insulin Response Over Surrogate Indices to Identify Genetic Contributors of Type 2 Diabetes: The GUARDIAN Consortium.Tissue-specific regulatory circuits reveal variable modular perturbations across complex diseases Insights into the genetic susceptibility to type 2 diabetes from genome-wide association studies of glycaemic traits.Mechanisms of Type 2 Diabetes Risk Loci.Tau deletion promotes brain insulin resistance An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.Common and rare forms of diabetes mellitus: towards a continuum of diabetes subtypes.Genetics of Type 2 Diabetes: It Matters From Which Parent We Inherit the Risk.Excess maternal transmission of variants in the THADA gene to offspring with type 2 diabetes.A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants.The Metabolic Syndrome in Men study: a resource for studies of metabolic and cardiovascular diseases.Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance.The PI3K Pathway in Human Disease.Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness.Ranking factors involved in diabetes remission after bariatric surgery using machine-learning integrating clinical and genomic biomarkers.Genetic Evidence That Carbohydrate-Stimulated Insulin Secretion Leads to Obesity.Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion: A DIRECT study.Biochemical and cellular properties of insulin receptor signalling.Disentangling the Role of Melatonin and its Receptor MTNR1B in Type 2 Diabetes: Still a Long Way to Go?Genetic analysis in UK Biobank links insulin resistance and transendothelial migration pathways to coronary artery disease.Genetic aetiology of glycaemic traits: approaches and insights.Genetic variants in sex hormone pathways and the risk of type 2 diabetes among African-American, Hispanic-American, and European-American postmenopausal women in the United States.New approaches beyond genetics: towards precision medicine in diabetes.Epigenetic marks of in utero exposure to gestational diabetes and childhood adiposity outcomes: the EPOCH study.Does epigenetic dysregulation of pancreatic islets contribute to impaired insulin secretion and type 2 diabetes?Genetic risk score of common genetic variants for impaired fasting glucose and newly diagnosed type 2 diabetes influences oxidative stress.An adult-based insulin resistance genetic risk score associates with insulin resistance, metabolic traits and altered fat distribution in Danish children and adolescents who are overweight or obese

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A central role for GRB10 in regulation of islet function in man.

http://www.wikidata.org/entity/Q31156020

description

2014 nî lūn-bûn

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2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի ապրիլին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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A central role for GRB10 in regulation of islet function in man.

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A central role for GRB10 in regulation of islet function in man.

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A central role for GRB10 in regulation of islet function in man.

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A central role for GRB10 in regulation of islet function in man.

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A central role for GRB10 in regulation of islet function in man.

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A central role for GRB10 in regulation of islet function in man.

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JOURNAL.PGEN.1004235

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A central role for GRB10 in regulation of islet function in man.

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Adam Barker

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Andrea Mari

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Cecile Lecoeur

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Claire Levy-Marchal

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Elisabeth Widen

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Emma Ahlqvist

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Hyun Min Kang

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Jalal Taneera

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Jeffrey R O'Connell

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Jie Liu

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P2860

The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes

PLINK: a tool set for whole-genome association and population-based linkage analyses

Reciprocal imprinting of human GRB10 in placental trophoblast and brain: evolutionary conservation of reversed allelic expression

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

A genome-wide association study identifies novel risk loci for type 2 diabetes

Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes

A new multipoint method for genome-wide association studies by imputation of genotypes

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e1004235

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scholarly article

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10.1371/JOURNAL.PGEN.1004235

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4

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Valeriya Lyssenko

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Rainer Rauramaa

Philippe Froguel

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2014-04-03T00:00:00Z

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261372078

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24699409

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3974640

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