Correlation of human jejunal permeability (in vivo) of drugs with experimentally and theoretically derived parameters. A multivariate data analysis approach.
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Sulforaphane as a potential protective phytochemical against neurodegenerative diseasesTreatment of intermediate stage hepatocellular carcinoma: a review of intrahepatic doxorubicin drug-delivery systemsTranslating Human Effective Jejunal Intestinal Permeability to Surface-Dependent Intrinsic Permeability: a Pragmatic Method for a More Mechanistic Prediction of Regional Oral Drug Absorption.In silico predictions of drug solubility and permeability: two rate-limiting barriers to oral drug absorption.A comparative evaluation of models to predict human intestinal metabolism from nonclinical data.High-throughput evaluation of relative cell permeability between peptoids and peptides.High-throughput screening approaches for investigating drug metabolism and pharmacokinetics.Biorelevant pK(a) (37 °C) predicted from the 2D structure of the molecule and its pK(a) at 25 °C.Intestinal drug absorption and bioavailability: beyond involvement of single transport function.Evaluation of the use of partition coefficients and molecular surface properties as predictors of drug absorption: a provisional biopharmaceutical classification of the list of national essential medicines of Pakistan.Pharmacokinetics and tolerability of different doses of fentanyl following sublingual administration of a rapidly dissolving tablet to cancer patients: a new approach to treatment of incident pain.The effect of ketoconazole on the in vivo intestinal permeability of fexofenadine using a regional perfusion technique.The use of biopharmaceutic classification of drugs in drug discovery and development: current status and future extension.In Vitro Assessment of Uptake and Lysosomal Sequestration of Respiratory Drugs in Alveolar Macrophage Cell Line NR8383Role of the equilibrative and concentrative nucleoside transporters in the intestinal absorption of the nucleoside drug, ribavirin, in wild-type and Ent1(-/-) mice.Computational models to predict aqueous drug solubility, permeability and intestinal absorption.Predictive models for oral drug absorption: from in silico methods to integrated dynamical models.Intestinal permeability and its relevance for absorption and elimination.Irregular gastrointestinal drug absorption in Parkinson's disease.Pharmacokinetics of the Antischistosomal Lead Ozonide OZ418 in Uninfected Mice Determined by Liquid Chromatography-Tandem Mass SpectrometryPrediction of solubility and permeability class membership: provisional BCS classification of the world's top oral drugsWhat has polar surface area ever done for drug discovery?Rethinking glycolysis: on the biochemical logic of metabolic pathways.In vitro-in vivo extrapolation (IVIVE) for predicting human intestinal absorption and first-pass elimination of drugs: principles and applications.Forecasting oral absorption across biopharmaceutics classification system classes with physiologically based pharmacokinetic models.Preventive and protective roles of dietary Nrf2 activators against central nervous system diseases.The Prediction of the Relative Importance of CYP3A/P-glycoprotein to the Nonlinear Intestinal Absorption of Drugs by Advanced Compartmental Absorption and Transit Model.Pharmacophore Identification, Molecular Docking, Virtual Screening, and In Silico ADME Studies of Non-Nucleoside Reverse Transcriptase Inhibitors.An HPLC-UV method for the measurement of permeability of marker drugs in the Caco-2 cell assay.Computational approaches for modeling human intestinal absorption and permeability.Cells on pores: a simulation-driven analysis of transcellular small molecule transport.Evaluation of a single-pass intestinal-perfusion method in rat for the prediction of absorption in man.Development of Heptylmannoside-Based Glycoconjugate Antiadhesive Compounds against Adherent-Invasive Escherichia coli Bacteria Associated with Crohn's Disease.Mass Spectrometry Imaging proves differential absorption profiles of well-characterised permeability markers along the crypt-villus axisRank order entropy: why one metric is not enoughA cell-based molecular transport simulator for pharmacokinetic prediction and cheminformatic exploration.Chemical substituent effect on pyridine permeability and mechanistic insight from computational molecular descriptors.No evidence for the involvement of the multidrug resistance-associated protein and/or the monocarboxylic acid transporter in the intestinal transport of fluvastatin in the ratEffects of cholesterol and model transmembrane proteins on drug partitioning into lipid bilayers as analysed by immobilized-liposome chromatography.The influence of caprate on rectal absorption of phenoxymethylpenicillin: experience from an in-vivo perfusion in humans.
P2860
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P2860
Correlation of human jejunal permeability (in vivo) of drugs with experimentally and theoretically derived parameters. A multivariate data analysis approach.
description
1998 nî lūn-bûn
@nan
1998 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Correlation of human jejunal p ...... ariate data analysis approach.
@ast
Correlation of human jejunal p ...... ariate data analysis approach.
@en
type
label
Correlation of human jejunal p ...... ariate data analysis approach.
@ast
Correlation of human jejunal p ...... ariate data analysis approach.
@en
prefLabel
Correlation of human jejunal p ...... ariate data analysis approach.
@ast
Correlation of human jejunal p ...... ariate data analysis approach.
@en
P2093
P356
P1476
Correlation of human jejunal p ...... ariate data analysis approach.
@en
P2093
P304
P356
10.1021/JM9810102
P407
P577
1998-12-01T00:00:00Z