Efficient construction of a large nonimmune phage antibody library: the production of high-affinity human single-chain antibodies to protein antigens - sprookjes - yvandenbroek - TriplyDB

Efficient construction of a large nonimmune phage antibody library: the production of high-affinity human single-chain antibodies to protein antigens

Efficient construction of a large nonimmune phage antibody library: the production of high-affinity human single-chain antibodies to protein antigens

http://www.wikidata.org/entity/Q32062847

about

The use of mRNA display to select high-affinity protein-binding peptides Human single-chain Fv intrabodies counteract in situ huntingtin aggregation in cellular models of Huntington's disease Eliminating helper phage from phage display A large semi-synthetic single-chain Fv phage display library based on chicken immunoglobulin genes Protein expression profiling arrays: tools for the multiplexed high-throughput analysis of proteins A Single-Domain Llama Antibody Potently Inhibits the Enzymatic Activity of Botulinum Neurotoxin by Binding to the Non-Catalytic α-Exosite Binding Region Structural insights into a human anti-IFN antibody exerting therapeutic potential for systemic lupus erythematosus Synthetic approach to the generation of antibody diversity Yeast mating for combinatorial Fab library generation and surface display Virus-based chemical and biological sensing.Disruption of anthrax toxin binding with the use of human antibodies and competitive inhibitors.Antibodies to human fetal erythroid cells from a nonimmune phage antibody library Intracellular stability of anti-caspase-3 intrabodies determines efficacy in retargeting the antigen.Continuous affinity-based selection: rapid screening and simultaneous amplification of bacterial surface-display libraries Epitope mapping of neutralizing botulinum neurotoxin A antibodies by phage display A large non-immunized human Fab fragment phage library that permits rapid isolation and kinetic analysis of high affinity antibodies.Human scFv antibody fragments specific for hepatocellular carcinoma selected from a phage display library.Generation and characterization of human monoclonal scFv antibodies against Helicobacter pylori antigens.A library of bacteriophage-displayed antibody fragments directed against proteins of the inner ear Flow-cytometric isolation of human antibodies from a nonimmune Saccharomyces cerevisiae surface display library.By-passing selection: direct screening for antibody-antigen interactions using protein arrays Recombining germline-derived CDR sequences for creating diverse single-framework antibody libraries.Antibody arrays for high-throughput screening of antibody-antigen interactions.Selecting open reading frames from DNA Phage display-selected sequences of the heavy-chain CDR3 loop of the anti-digoxin antibody 26-10 define a high affinity binding site for position 16-substituted analogs of digoxin.Applications of display technology in protein analysis.Recombinatorial cloning using heterologous lox sites.Human combinatorial Fab library yielding specific and functional antibodies against the human fibroblast growth factor receptor 3.Exploiting recombination in single bacteria to make large phage antibody libraries.Alpha-amylase inhibitors selected from a combinatorial library of a cellulose binding domain scaffold.Single-chain variable fragments selected on the 57-76 p21Ras neutralising epitope from phage antibody libraries recognise the parental protein.A method for the generation of combinatorial antibody libraries using pIX phage display Selection and characterisation of binders based on homodimerisation of immunoglobulin V(H) domains.Isolation of human monoclonal antibodies that neutralize human rotavirus An antibody library for stabilizing and crystallizing membrane proteins - selecting binders to the citrate carrier CitS.Using phage display to select antibodies recognizing post-translational modifications independently of sequence context.A novel assay for monitoring internalization of nanocarrier coupled antibodies.Obligate multivalent recognition of cell surface tomoregulin following selection from a multivalent phage antibody library.Synthetic antibodies as therapeutics.Identification and characterization of tumor antigens by using antibody phage display and intrabody strategies.

P2860

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P2860

Efficient construction of a large nonimmune phage antibody library: the production of high-affinity human single-chain antibodies to protein antigens

http://www.wikidata.org/entity/Q32062847

description

1998 nî lūn-bûn

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1998 թուականի Մայիսին հրատարակուած գիտական յօդուած

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1998 թվականի մայիսին հրատարակված գիտական հոդված

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1998年の論文

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1998年論文

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1998年論文

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1998年論文

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1998年論文

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1998年論文

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1998年论文

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Proceedings of the National Academy of Sciences of the United States of America

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Efficient construction of a la ...... antibodies to protein antigens

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C Wong

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E Lindquist

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G Hemingsen

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P2860

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product

Selection of phage antibodies by binding affinity. Mimicking affinity maturation

By-passing immunization. Human antibodies from V-gene libraries displayed on phage.

Human antibodies with sub-nanomolar affinities isolated from a large non-immunized phage display library.

The repertoire of human germline VH sequences reveals about fifty groups of VH segments with different hypervariable loops.

Making antibody fragments using phage display libraries.

Multi-subunit proteins on the surface of filamentous phage: methodologies for displaying antibody (Fab) heavy and light chains

Protein engineering of antibody binding sites: recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Escherichia coli

Regulation of the fibroblast growth factor receptor in early Xenopus embryos.

Phage antibodies: filamentous phage displaying antibody variable domains.

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